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Proteomics and phylogenetic analysis of the cathepsin L protease family of the helminth pathogen Fasciola hepatica: expansion of a repertoire of virulence-associated factors. [electronic resource] by
- Robinson, Mark W
- Tort, Jose F
- Lowther, Jonathan
- Donnelly, Sheila M
- Wong, Emily
- Xu, Weibo
- Stack, Colin M
- Padula, Matthew
- Herbert, Ben
- Dalton, John P
Producer: 20080821
In:
Molecular & cellular proteomics : MCP vol. 7
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Leucine aminopeptidase of the human blood flukes, Schistosoma mansoni and Schistosoma japonicum. [electronic resource] by
- McCarthy, Elaine
- Stack, Colin
- Donnelly, Sheila M
- Doyle, Sean
- Mann, Victoria H
- Brindley, Paul J
- Stewart, Michael
- Day, Tim A
- Maule, Aaron G
- Dalton, John P
Producer: 20040928
In:
International journal for parasitology vol. 34
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25.
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Identification of phosphinate dipeptide analog inhibitors directed against the Plasmodium falciparum M17 leucine aminopeptidase as lead antimalarial compounds. [electronic resource] by
- Skinner-Adams, Tina S
- Lowther, Jonathan
- Teuscher, Franka
- Stack, Colin M
- Grembecka, Jolanta
- Mucha, Artur
- Kafarski, Pawel
- Trenholme, Katharine R
- Dalton, John P
- Gardiner, Donald L
Producer: 20080227
In:
Journal of medicinal chemistry vol. 50
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Aminopeptidases of malaria parasites: new targets for chemotherapy. [electronic resource] by
- Trenholme, Katharine R
- Brown, Christopher L
- Skinner-Adams, Tina S
- Stack, Colin
- Lowther, Jonathan
- To, Joyce
- Robinson, Mark W
- Donnelly, Sheila M
- Dalton, John P
- Gardiner, Donald L
Producer: 20100803
In:
Infectious disorders drug targets vol. 10
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28.
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Cathepsin L1, the major protease involved in liver fluke (Fasciola hepatica) virulence: propetide cleavage sites and autoactivation of the zymogen secreted from gastrodermal cells. [electronic resource] by
- Collins, Peter R
- Stack, Colin M
- O'Neill, Sandra M
- Doyle, Sean
- Ryan, Thecla
- Brennan, Gerard P
- Mousley, Angela
- Stewart, Michael
- Maule, Aaron G
- Dalton, John P
- Donnelly, Sheila
Producer: 20040610
In:
The Journal of biological chemistry vol. 279
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29.
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The aminopeptidase inhibitor CHR-2863 is an orally bioavailable inhibitor of murine malaria. [electronic resource] by
- Skinner-Adams, Tina S
- Peatey, Christopher L
- Anderson, Karen
- Trenholme, Katharine R
- Krige, David
- Brown, Christopher L
- Stack, Colin
- Nsangou, Desire M M
- Mathews, Rency T
- Thivierge, Karine
- Dalton, John P
- Gardiner, Donald L
Producer: 20120913
In:
Antimicrobial agents and chemotherapy vol. 56
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30.
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The M18 aspartyl aminopeptidase of the human malaria parasite Plasmodium falciparum. [electronic resource] by
- Teuscher, Franka
- Lowther, Jonathan
- Skinner-Adams, Tina S
- Spielmann, Tobias
- Dixon, Matthew W A
- Stack, Colin M
- Donnelly, Sheila
- Mucha, Artur
- Kafarski, Paweł
- Vassiliou, Stamatia
- Gardiner, Donald L
- Dalton, John P
- Trenholme, Katharine R
Producer: 20071212
In:
The Journal of biological chemistry vol. 282
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31.
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Characterization of the Plasmodium falciparum M17 leucyl aminopeptidase. A protease involved in amino acid regulation with potential for antimalarial drug development. [electronic resource] by
- Stack, Colin M
- Lowther, Jonathan
- Cunningham, Eithne
- Donnelly, Sheila
- Gardiner, Donald L
- Trenholme, Katharine R
- Skinner-Adams, Tina S
- Teuscher, Franka
- Grembecka, Jolanta
- Mucha, Artur
- Kafarski, Pawel
- Lua, Linda
- Bell, Angus
- Dalton, John P
Producer: 20070227
In:
The Journal of biological chemistry vol. 282
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32.
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Plasmodium falciparum neutral aminopeptidases: new targets for anti-malarials. [electronic resource] by
- Skinner-Adams, Tina S
- Stack, Colin M
- Trenholme, Katharine R
- Brown, Chris L
- Grembecka, Jolanta
- Lowther, Jonathan
- Mucha, Artur
- Drag, Marcin
- Kafarski, Pawel
- McGowan, Sheena
- Whisstock, James C
- Gardiner, Donald L
- Dalton, John P
Producer: 20100217
In:
Trends in biochemical sciences vol. 35
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33.
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Fasciola hepatica cathepsin L-like proteases: biology, function, and potential in the development of first generation liver fluke vaccines. [electronic resource] by
- Dalton, John P
- Neill, Sandra O
- Stack, Colin
- Collins, Peter
- Walshe, Alan
- Sekiya, Mary
- Doyle, Sean
- Mulcahy, Grace
- Hoyle, Deborah
- Khaznadji, Eric
- Moiré, Nathalie
- Brennan, Gerard
- Mousley, Angela
- Kreshchenko, Natalia
- Maule, Aaron G
- Donnelly, Sheila M
Producer: 20040107
In:
International journal for parasitology vol. 33
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34.
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A Plasmodium falciparum S33 proline aminopeptidase is associated with changes in erythrocyte deformability. [electronic resource] by
- da Silva, Fabio L
- Dixon, Matthew W A
- Stack, Colin M
- Teuscher, Franka
- Taran, Elena
- Jones, Malcolm K
- Lovas, Erica
- Tilley, Leann
- Brown, Christopher L
- Trenholme, Katharine R
- Dalton, John P
- Gardiner, Donald L
- Skinner-Adams, Tina S
Producer: 20170215
In:
Experimental parasitology vol. 169
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35.
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Structure of the Plasmodium falciparum M17 aminopeptidase and significance for the design of drugs targeting the neutral exopeptidases. [electronic resource] by
- McGowan, Sheena
- Oellig, Christine A
- Birru, Woldeamanuel A
- Caradoc-Davies, Tom T
- Stack, Colin M
- Lowther, Jonathan
- Skinner-Adams, Tina
- Mucha, Artur
- Kafarski, Pawel
- Grembecka, Jolanta
- Trenholme, Katharine R
- Buckle, Ashley M
- Gardiner, Donald L
- Dalton, John P
- Whisstock, James C
Producer: 20100507
In:
Proceedings of the National Academy of Sciences of the United States of America vol. 107
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Squamous cell carcinoma antigen 1 is an inhibitor of parasite-derived cysteine proteases. [electronic resource] by
- Kanaji, Sachiko
- Tanaka, Yoko
- Sakata, Yasuhisa
- Takeshita, Kohei
- Arima, Kazuhiko
- Ohta, Shoichiro
- Hansell, Elizabeth J
- Caffrey, Conor
- Mottram, Jeremy C
- Lowther, Jonathan
- Donnelly, Sheila
- Stack, Colin
- Kadowaki, Tomoko
- Yamamoto, Kenji
- McKerrow, James H
- Dalton, John P
- Coombs, Graham H
- Izuhara, Kenji
Producer: 20071019
In:
FEBS letters vol. 581
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37.
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Structural and functional relationships in the virulence-associated cathepsin L proteases of the parasitic liver fluke, Fasciola hepatica. [electronic resource] by
- Stack, Colin M
- Caffrey, Conor R
- Donnelly, Sheila M
- Seshaadri, Amritha
- Lowther, Jonathan
- Tort, Jose F
- Collins, Peter R
- Robinson, Mark W
- Xu, Weibo
- McKerrow, James H
- Craik, Charles S
- Geiger, Sebastian R
- Marion, Rachel
- Brinen, Linda S
- Dalton, John P
Producer: 20080528
In:
The Journal of biological chemistry vol. 283
Availability: No items available.
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38.
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Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidase. [electronic resource] by
- McGowan, Sheena
- Porter, Corrine J
- Lowther, Jonathan
- Stack, Colin M
- Golding, Sarah J
- Skinner-Adams, Tina S
- Trenholme, Katharine R
- Teuscher, Franka
- Donnelly, Sheila M
- Grembecka, Jolanta
- Mucha, Artur
- Kafarski, Pawel
- Degori, Ross
- Buckle, Ashley M
- Gardiner, Donald L
- Whisstock, James C
- Dalton, John P
Producer: 20090406
In:
Proceedings of the National Academy of Sciences of the United States of America vol. 106
Availability: No items available.
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