Results
|
21.
|
Identification of aminopiperidine benzamides as MCHr1 antagonists. [electronic resource] by
- Vasudevan, Anil
- Verzal, Mary K
- Wodka, Derek
- Souers, Andrew J
- Blackburn, Christopher
- Che, Jennifer Lee
- Lai, Sujen
- Brodjian, Sevan
- Falls, Doug H
- Dayton, Brian D
- Govek, Elizabeth
- Daniels, Tom
- Geddes, Brad
- Marsh, Kennan C
- Hernandez, Lisa E
- Collins, Christine A
- Kym, Philip R
Producer: 20051219
In:
Bioorganic & medicinal chemistry letters vol. 15
Availability: No items available.
|
|
22.
|
Targeted inhibition of histone H3K27 demethylation is effective in high-risk neuroblastoma. [electronic resource] by
- Lochmann, Timothy L
- Powell, Krista M
- Ham, Jungoh
- Floros, Konstantinos V
- Heisey, Daniel A R
- Kurupi, Richard I J
- Calbert, Marissa L
- Ghotra, Maninderjit S
- Greninger, Patricia
- Dozmorov, Mikhail
- Gowda, Madhu
- Souers, Andrew J
- Reynolds, C Patrick
- Benes, Cyril H
- Faber, Anthony C
Producer: 20190920
In:
Science translational medicine vol. 10
Availability: No items available.
|
|
23.
|
Synthesis and evaluation of urea-based indazoles as melanin-concentrating hormone receptor 1 antagonists for the treatment of obesity. [electronic resource] by
- Souers, Andrew J
- Gao, Ju
- Wodka, Dariusz
- Judd, Andrew S
- Mulhern, Mathew M
- Napier, James J
- Brune, Michael E
- Bush, Eugene N
- Brodjian, Sevan J
- Dayton, Brian D
- Shapiro, Robin
- Hernandez, Lisa E
- Marsh, Kennan C
- Sham, Hing L
- Collins, Christine A
- Kym, Philip R
Producer: 20051031
In:
Bioorganic & medicinal chemistry letters vol. 15
Availability: No items available.
|
|
24.
|
Lack of efficacy of melanin-concentrating hormone-1 receptor antagonists in models of depression and anxiety. [electronic resource] by
- Basso, Ana M
- Bratcher, Natalie A
- Gallagher, Kelly B
- Cowart, Marlon D
- Zhao, Chen
- Sun, Minghua
- Esbenshade, Timothy A
- Brune, Michael E
- Fox, Gerard B
- Schmidt, Martin
- Collins, Christine A
- Souers, Andrew J
- Iyengar, Rajesh
- Vasudevan, Anil
- Kym, Philip R
- Hancock, Arthur A
- Rueter, Lynne E
Producer: 20061211
In:
European journal of pharmacology vol. 540
Availability: No items available.
|
|
25.
|
Expression Profile of BCL-2, BCL-XL, and MCL-1 Predicts Pharmacological Response to the BCL-2 Selective Antagonist Venetoclax in Multiple Myeloma Models. [electronic resource] by
- Punnoose, Elizabeth A
- Leverson, Joel D
- Peale, Franklin
- Boghaert, Erwin R
- Belmont, Lisa D
- Tan, Nguyen
- Young, Amy
- Mitten, Michael
- Ingalla, Ellen
- Darbonne, Walter C
- Oleksijew, Anatol
- Tapang, Paul
- Yue, Peng
- Oeh, Jason
- Lee, Leslie
- Maiga, Sophie
- Fairbrother, Wayne J
- Amiot, Martine
- Souers, Andrew J
- Sampath, Deepak
Producer: 20170629
In:
Molecular cancer therapeutics vol. 15
Availability: No items available.
|
|
26.
|
The Ewing Family of Tumors Relies on BCL-2 and BCL-X [electronic resource] by
- Heisey, Daniel A R
- Lochmann, Timothy L
- Floros, Konstantinos V
- Coon, Colin M
- Powell, Krista M
- Jacob, Sheeba
- Calbert, Marissa L
- Ghotra, Maninderjit S
- Stein, Giovanna T
- Maves, Yuki Kato
- Smith, Steven C
- Benes, Cyril H
- Leverson, Joel D
- Souers, Andrew J
- Boikos, Sosipatros A
- Faber, Anthony C
Producer: 20200408
In:
Clinical cancer research : an official journal of the American Association for Cancer Research vol. 25
Availability: No items available.
|
|
27.
|
Quinazoline sulfonamides as dual binders of the proteins B-cell lymphoma 2 and B-cell lymphoma extra long with potent proapoptotic cell-based activity. [electronic resource] by
- Sleebs, Brad E
- Czabotar, Peter E
- Fairbrother, Wayne J
- Fairlie, W Douglas
- Flygare, John A
- Huang, David C S
- Kersten, Wilhelmus J A
- Koehler, Michael F T
- Lessene, Guillaume
- Lowes, Kym
- Parisot, John P
- Smith, Brian J
- Smith, Morey L
- Souers, Andrew J
- Street, Ian P
- Yang, Hong
- Baell, Jonathan B
Producer: 20110617
In:
Journal of medicinal chemistry vol. 54
Availability: No items available.
|
|
28.
|
A novel CDK9 inhibitor increases the efficacy of venetoclax (ABT-199) in multiple models of hematologic malignancies. [electronic resource] by
- Phillips, Darren C
- Jin, Sha
- Gregory, Gareth P
- Zhang, Qi
- Xue, John
- Zhao, Xiaoxian
- Chen, Jun
- Tong, Yunsong
- Zhang, Haichao
- Smith, Morey
- Tahir, Stephen K
- Clark, Rick F
- Penning, Thomas D
- Devlin, Jennifer R
- Shortt, Jake
- Hsi, Eric D
- Albert, Daniel H
- Konopleva, Marina
- Johnstone, Ricky W
- Leverson, Joel D
- Souers, Andrew J
Producer: 20201007
In:
Leukemia vol. 34
Availability: No items available.
|
|
29.
|
Venetoclax Is Effective in Small-Cell Lung Cancers with High BCL-2 Expression. [electronic resource] by
- Lochmann, Timothy L
- Floros, Konstantinos V
- Naseri, Mitra
- Powell, Krista M
- Cook, Wade
- March, Ryan J
- Stein, Giovanna T
- Greninger, Patricia
- Maves, Yuki Kato
- Saunders, Laura R
- Dylla, Scott J
- Costa, Carlotta
- Boikos, Sosipatros A
- Leverson, Joel D
- Souers, Andrew J
- Krystal, Geoffrey W
- Harada, Hisashi
- Benes, Cyril H
- Faber, Anthony C
Producer: 20190724
In:
Clinical cancer research : an official journal of the American Association for Cancer Research vol. 24
Availability: No items available.
|
|
30.
|
Aminopiperidine indazoles as orally efficacious melanin concentrating hormone receptor-1 antagonists. [electronic resource] by
- Vasudevan, Anil
- Souers, Andrew J
- Freeman, Jennifer C
- Verzal, Mary K
- Gao, Ju
- Mulhern, Mathew M
- Wodka, Derek
- Lynch, John K
- Engstrom, Kenneth M
- Wagaw, Seble H
- Brodjian, Sevan
- Dayton, Brian
- Falls, Doug H
- Bush, Eugene
- Brune, Michael
- Shapiro, Robin D
- Marsh, Kennan C
- Hernandez, Lisa E
- Collins, Christine A
- Kym, Philip R
Producer: 20060123
In:
Bioorganic & medicinal chemistry letters vol. 15
Availability: No items available.
|
|
31.
|
Increased Synthesis of MCL-1 Protein Underlies Initial Survival of [electronic resource] by
- Song, Kyung-A
- Hosono, Yasuyuki
- Turner, Crystal
- Jacob, Sheeba
- Lochmann, Timothy L
- Murakami, Yoshiko
- Patel, Neha U
- Ham, Jungoh
- Hu, Bin
- Powell, Krista M
- Coon, Colin M
- Windle, Brad E
- Oya, Yuko
- Koblinski, Jennifer E
- Harada, Hisashi
- Leverson, Joel D
- Souers, Andrew J
- Hata, Aaron N
- Boikos, Sosipatros
- Yatabe, Yasushi
- Ebi, Hiromichi
- Faber, Anthony C
Producer: 20191118
In:
Clinical cancer research : an official journal of the American Association for Cancer Research vol. 24
Availability: No items available.
|
|
32.
|
An evaluation of 3,4-methylenedioxy phenyl replacements in the aminopiperidine chromone class of MCHr1 antagonists. [electronic resource] by
- Iyengar, Rajesh R
- Lynch, John K
- Mulhern, Mathew M
- Judd, Andrew S
- Freeman, Jennifer C
- Gao, Ju
- Souers, Andrew J
- Zhao, Gang
- Wodka, Dariusz
- Doug Falls, H
- Brodjian, Sevan
- Dayton, Brian D
- Reilly, Regina M
- Swanson, Sue
- Su, Zhi
- Martin, Ruth L
- Leitza, Sandra T
- Houseman, Kathryn A
- Diaz, Gilbert
- Collins, Christine A
- Sham, Hing L
- Kym, Philip R
Producer: 20070413
In:
Bioorganic & medicinal chemistry letters vol. 17
Availability: No items available.
|
|
33.
|
Coamplification of [electronic resource] by
- Floros, Konstantinos V
- Lochmann, Timothy L
- Hu, Bin
- Monterrubio, Carles
- Hughes, Mark T
- Wells, Jason D
- Morales, Cristina Bernadó
- Ghotra, Maninderjit S
- Costa, Carlotta
- Souers, Andrew J
- Boikos, Sosipatros A
- Leverson, Joel D
- Tan, Ming
- Serra, Violeta
- Koblinski, Jennifer E
- Arribas, Joaquin
- Prat, Aleix
- Paré, Laia
- Miller, Todd W
- Dozmorov, Mikhail G
- Harada, Hisashi
- Windle, Brad E
- Scaltriti, Maurizio
- Faber, Anthony C
Producer: 20180730
In:
Proceedings of the National Academy of Sciences of the United States of America vol. 115
Availability: No items available.
|
|
34.
|
Identification of ortho-amino benzamides and nicotinamides as MCHr1 antagonists. [electronic resource] by
- Vasudevan, Anil
- LaMarche, Matthew J
- Blackburn, Christopher
- Che, Jennifer Lee
- Luchaco-Cullis, Courtney A
- Lai, Sujen
- Marsilje, Thomas H
- Patane, Michael A
- Souers, Andrew J
- Wodka, Derek
- Geddes, Bradley
- Chen, Sumiao
- Brodjian, Seven
- Falls, Doug H
- Dayton, Brian D
- Bush, Eugene
- Brune, Michael
- Shapiro, Robin D
- Marsh, Kennan C
- Hernandez, Lisa E
- Sham, Hing L
- Collins, Christine A
- Kym, Philip R
Producer: 20051220
In:
Bioorganic & medicinal chemistry letters vol. 15
Availability: No items available.
|
|
35.
|
Screening for cardiovascular safety: a structure-activity approach for guiding lead selection of melanin concentrating hormone receptor 1 antagonists. [electronic resource] by
- Kym, Philip R
- Souers, Andrew J
- Campbell, Thomas J
- Lynch, John K
- Judd, Andrew S
- Iyengar, Rajesh
- Vasudevan, Anil
- Gao, Ju
- Freeman, Jennifer C
- Wodka, Dariusz
- Mulhern, Mathew
- Zhao, Gang
- Wagaw, Seble H
- Napier, James J
- Brodjian, Sevan
- Dayton, Brian D
- Reilly, Regina M
- Segreti, Jason A
- Fryer, Ryan M
- Preusser, Lee C
- Reinhart, Glenn A
- Hernandez, Lisa
- Marsh, Kennan C
- Sham, Hing L
- Collins, Christine A
- Polakowski, James S
Producer: 20060502
In:
Journal of medicinal chemistry vol. 49
Availability: No items available.
|
|
36.
|
Structure-guided design of a series of MCL-1 inhibitors with high affinity and selectivity. [electronic resource] by
- Bruncko, Milan
- Wang, Le
- Sheppard, George S
- Phillips, Darren C
- Tahir, Stephen K
- Xue, John
- Erickson, Scott
- Fidanze, Steve
- Fry, Elizabeth
- Hasvold, Lisa
- Jenkins, Gary J
- Jin, Sha
- Judge, Russell A
- Kovar, Peter J
- Madar, David
- Nimmer, Paul
- Park, Chang
- Petros, Andrew M
- Rosenberg, Saul H
- Smith, Morey L
- Song, Xiaohong
- Sun, Chaohong
- Tao, Zhi-Fu
- Wang, Xilu
- Xiao, Yu
- Zhang, Haichao
- Tse, Chris
- Leverson, Joel D
- Elmore, Steven W
- Souers, Andrew J
Producer: 20150615
In:
Journal of medicinal chemistry vol. 58
Availability: No items available.
|
|
37.
|
Structure-Guided Rescaffolding of Selective Antagonists of BCL-XL. [electronic resource] by
- Koehler, Michael F T
- Bergeron, Philippe
- Choo, Edna F
- Lau, Kevin
- Ndubaku, Chudi
- Dudley, Danette
- Gibbons, Paul
- Sleebs, Brad E
- Rye, Carl S
- Nikolakopoulos, George
- Bui, Chinh
- Kulasegaram, Sanji
- Kersten, Wilhelmus J A
- Smith, Brian J
- Czabotar, Peter E
- Colman, Peter M
- Huang, David C S
- Baell, Jonathan B
- Watson, Keith G
- Hasvold, Lisa
- Tao, Zhi-Fu
- Wang, Le
- Souers, Andrew J
- Elmore, Steven W
- Flygare, John A
- Fairbrother, Wayne J
- Lessene, Guillaume
Producer: 20140619
In:
ACS medicinal chemistry letters vol. 5
Availability: No items available.
|
|
38.
|
Correction to Structure-Guided Design of a Series of MCL-1 Inhibitors with High Affinity and Selectivity. [electronic resource] by
- Bruncko, Milan
- Wang, Le
- Sheppard, George S
- Phillips, Darren C
- Tahir, Stephen K
- Xue, John
- Erickson, Scott
- Fidanze, Steve
- Fry, Elizabeth
- Hasvold, Lisa
- Jenkins, Gary J
- Jin, Sha
- Judge, Russell A
- Kovar, Peter J
- Madar, David
- Nimmer, Paul
- Park, Chang
- Petros, Andrew M
- Rosenberg, Saul H
- Smith, Morey L
- Song, Xiaohong
- Sun, Chaohong
- Tao, Zhi-Fu
- Wang, Xilu
- Xiao, Yu
- Zhang, Haichao
- Tse, Chris
- Leverson, Joel D
- Elmore, Steven W
- Souers, Andrew J
Producer: 20150716
In:
Journal of medicinal chemistry vol. 58
Availability: No items available.
|
|
39.
|
Identification of diamino chromone-2-carboxamides as MCHr1 antagonists with minimal hERG channel activity. [electronic resource] by
- Judd, Andrew S
- Souers, Andrew J
- Wodka, Dariusz
- Zhao, Gang
- Mulhern, Mathew M
- Iyengar, Rajesh R
- Gao, Ju
- Lynch, John K
- Freeman, Jennifer C
- Falls, H Douglas
- Brodjian, Sevan
- Dayton, Brian D
- Reilly, Regina M
- Gintant, Gary
- Limberis, James T
- Mikhail, Ann
- Leitza, Sandra T
- Houseman, Kathryn A
- Diaz, Gilbert
- Bush, Eugene N
- Shapiro, Robin
- Knourek-Segel, Victoria
- Hernandez, Lisa E
- Marsh, Kennan C
- Sham, Hing L
- Collins, Christine A
- Kym, Philip R
Producer: 20070530
In:
Bioorganic & medicinal chemistry letters vol. 17
Availability: No items available.
|
|
40.
|
Constrained 7-fluorocarboxychromone-4-aminopiperidine based Melanin-concentrating hormone receptor 1 antagonists: the effects of chirality on substituted indan-1-ylamines. [electronic resource] by
- Souers, Andrew J
- Iyengar, Rajesh R
- Judd, Andrew S
- Beno, David W A
- Gao, Ju
- Zhao, Gang
- Brune, Michael E
- Napier, James J
- Mulhern, Mathew M
- Lynch, John K
- Freeman, Jennifer C
- Wodka, Dariusz
- Chen, Chong J
- Falls, H Doug
- Brodjian, Sevan
- Dayton, Brian D
- Diaz, Gilbert J
- Bush, Eugene N
- Shapiro, Robin
- Droz, Brian A
- Knourek-Segel, Victoria
- Hernandez, Lisa E
- Marsh, Kennan C
- Reilly, Regina M
- Sham, Hing L
- Collins, Christine A
- Kym, Philip R
Producer: 20070413
In:
Bioorganic & medicinal chemistry letters vol. 17
Availability: No items available.
|