Results
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Engineering a Multifunctional Nitroreductase for Improved Activation of Prodrugs and PET Probes for Cancer Gene Therapy. [electronic resource] by
- Copp, Janine N
- Mowday, Alexandra M
- Williams, Elsie M
- Guise, Christopher P
- Ashoorzadeh, Amir
- Sharrock, Abigail V
- Flanagan, Jack U
- Smaill, Jeff B
- Patterson, Adam V
- Ackerley, David F
Producer: 20171121
In:
Cell chemical biology vol. 24
Availability: No items available.
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23.
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1-Benzyl-4-phenyl-1H-1,2,3-triazoles improve the transcriptional functions of estrogen-related receptor γ and promote the browning of white adipose. [electronic resource] by
- Xu, Shilin
- Mao, Liufeng
- Ding, Ping
- Zhuang, Xiaoxi
- Zhou, Yang
- Yu, Lei
- Liu, Yingxue
- Nie, Tao
- Xu, Tingting
- Xu, Yong
- Liu, Jinsong
- Smaill, Jeff
- Ren, Xiaomei
- Wu, Donghai
- Ding, Ke
Producer: 20160229
In:
Bioorganic & medicinal chemistry vol. 23
Availability: No items available.
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24.
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Engineering [electronic resource] by
- Williams, Elsie M
- Rich, Michelle H
- Mowday, Alexandra M
- Ashoorzadeh, Amir
- Copp, Janine N
- Guise, Christopher P
- Anderson, Robert F
- Flanagan, Jack U
- Smaill, Jeff B
- Patterson, Adam V
- Ackerley, David F
Producer: 20200608
In:
Biochemistry vol. 58
Availability: No items available.
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25.
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N-(3-Ethynyl-2,4-difluorophenyl)sulfonamide Derivatives as Selective Raf Inhibitors. [electronic resource] by
- Li, Yingjun
- Cheng, Huimin
- Zhang, Zhang
- Zhuang, Xiaoxi
- Luo, Jinfeng
- Long, Huoyou
- Zhou, Yang
- Xu, Yong
- Taghipouran, Rana
- Li, Dan
- Patterson, Adam
- Smaill, Jeff
- Tu, Zhengchao
- Wu, Donghai
- Ren, Xiaomei
- Ding, Ke
Producer: 20150525
In:
ACS medicinal chemistry letters vol. 6
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26.
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Discovery and optimization of 1-(1H-indol-1-yl)ethanone derivatives as CBP/EP300 bromodomain inhibitors for the treatment of castration-resistant prostate cancer. [electronic resource] by
- Xiang, Qiuping
- Wang, Chao
- Zhang, Yan
- Xue, Xiaoqian
- Song, Ming
- Zhang, Cheng
- Li, Chenchang
- Wu, Chun
- Li, Kuai
- Hui, Xiaoyan
- Zhou, Yulai
- Smaill, Jeff B
- Patterson, Adam V
- Wu, Donghai
- Ding, Ke
- Xu, Yong
Producer: 20180321
In:
European journal of medicinal chemistry vol. 147
Availability: No items available.
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27.
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4-Phenylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione inhibitors of the checkpoint kinase Wee1. Structure-activity relationships for chromophore modification and phenyl ring substitution. [electronic resource] by
- Palmer, Brian D
- Thompson, Andrew M
- Booth, R John
- Dobrusin, Ellen M
- Kraker, Alan J
- Lee, Ho H
- Lunney, Elizabeth A
- Mitchell, Lorna H
- Ortwine, Daniel F
- Smaill, Jeff B
- Swan, Leesa M
- Denny, William A
Producer: 20060913
In:
Journal of medicinal chemistry vol. 49
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28.
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Rational design of an AKR1C3-resistant analog of PR-104 for enzyme-prodrug therapy. [electronic resource] by
- Mowday, Alexandra M
- Ashoorzadeh, Amir
- Williams, Elsie M
- Copp, Janine N
- Silva, Shevan
- Bull, Matthew R
- Abbattista, Maria R
- Anderson, Robert F
- Flanagan, Jack U
- Guise, Christopher P
- Ackerley, David F
- Smaill, Jeff B
- Patterson, Adam V
Producer: 20170509
In:
Biochemical pharmacology vol. 116
Availability: No items available.
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29.
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Creation and screening of a multi-family bacterial oxidoreductase library to discover novel nitroreductases that efficiently activate the bioreductive prodrugs CB1954 and PR-104A. [electronic resource] by
- Prosser, Gareth A
- Copp, Janine N
- Mowday, Alexandra M
- Guise, Christopher P
- Syddall, Sophie P
- Williams, Elsie M
- Horvat, Claire N
- Swe, Pearl M
- Ashoorzadeh, Amir
- Denny, William A
- Smaill, Jeff B
- Patterson, Adam V
- Ackerley, David F
Producer: 20130516
In:
Biochemical pharmacology vol. 85
Availability: No items available.
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30.
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2-Oxo-3, 4-dihydropyrimido[4, 5-d]pyrimidinyl derivatives as new irreversible pan fibroblast growth factor receptor (FGFR) inhibitors. [electronic resource] by
- Li, Xueqiang
- Guise, Christopher P
- Taghipouran, Rana
- Yosaatmadja, Yuliana
- Ashoorzadeh, Amir
- Paik, Woo-Kyong
- Squire, Christopher J
- Jiang, Shuang
- Luo, Jinfeng
- Xu, Yong
- Tu, Zheng-Chao
- Lu, Xiaoyun
- Ren, Xiaomei
- Patterson, Adam V
- Smaill, Jeff B
- Ding, Ke
Producer: 20170928
In:
European journal of medicinal chemistry vol. 135
Availability: No items available.
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31.
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The synthesis and biological evaluation of novel series of nitrile-containing fluoroquinolones as antibacterial agents. [electronic resource] by
- Murphy, Sean T
- Case, Heather L
- Ellsworth, Edmund
- Hagen, Susan
- Huband, Michael
- Joannides, Themis
- Limberakis, Chris
- Marotti, Keith R
- Ottolini, Amy M
- Rauckhorst, Mark
- Starr, Jeremy
- Stier, Michael
- Taylor, Clarke
- Zhu, Tong
- Blaser, Adrian
- Denny, William A
- Lu, Guo-Liang
- Smaill, Jeff B
- Rivault, Freddy
Producer: 20070530
In:
Bioorganic & medicinal chemistry letters vol. 17
Availability: No items available.
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32.
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Synthesis and structure-activity relationships of N-6 substituted analogues of 9-hydroxy-4-phenylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones as inhibitors of Wee1 and Chk1 checkpoint kinases. [electronic resource] by
- Smaill, Jeff B
- Baker, Edward N
- Booth, R John
- Bridges, Alexander J
- Dickson, James M
- Dobrusin, Ellen M
- Ivanovic, Ivan
- Kraker, Alan J
- Lee, Ho H
- Lunney, Elizabeth A
- Ortwine, Daniel F
- Palmer, Brian D
- Quin, John
- Squire, Christopher J
- Thompson, Andrew M
- Denny, William A
Producer: 20080903
In:
European journal of medicinal chemistry vol. 43
Availability: No items available.
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33.
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Tyrosine kinase inhibitors. 19. 6-Alkynamides of 4-anilinoquinazolines and 4-anilinopyrido[3,4-d]pyrimidines as irreversible inhibitors of the erbB family of tyrosine kinase receptors. [electronic resource] by
- Klutchko, Sylvester R
- Zhou, Hairong
- Winters, R Thomas
- Tran, Tuan P
- Bridges, Alexander J
- Althaus, Irene W
- Amato, Danielle M
- Elliott, William L
- Ellis, Paul A
- Meade, Mary Ann
- Roberts, Billy J
- Fry, David W
- Gonzales, Andrea J
- Harvey, Patricia J
- Nelson, James M
- Sherwood, Veronica
- Han, Hyo-Kyung
- Pace, Gerry
- Smaill, Jeff B
- Denny, William A
- Showalter, H D Hollis
Producer: 20060410
In:
Journal of medicinal chemistry vol. 49
Availability: No items available.
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34.
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Tyrosine Kinase Inhibitors. 20. Optimization of Substituted Quinazoline and Pyrido[3,4-d]pyrimidine Derivatives as Orally Active, Irreversible Inhibitors of the Epidermal Growth Factor Receptor Family. [electronic resource] by
- Smaill, Jeff B
- Gonzales, Andrea J
- Spicer, Julie A
- Lee, Helen
- Reed, Jessica E
- Sexton, Karen
- Althaus, Irene W
- Zhu, Tong
- Black, Shannon L
- Blaser, Adrian
- Denny, William A
- Ellis, Paul A
- Fakhoury, Stephen
- Harvey, Patricia J
- Hook, Ken
- McCarthy, Florence O J
- Palmer, Brian D
- Rivault, Freddy
- Schlosser, Kevin
- Ellis, Teresa
- Thompson, Andrew M
- Trachet, Erin
- Winters, R Thomas
- Tecle, Haile
- Bridges, Alexander
Producer: 20170710
In:
Journal of medicinal chemistry vol. 59
Availability: No items available.
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