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	21.	Orally bioavailable pyridine and pyrimidine-based Factor XIa inhibitors: Discovery of the methyl N-phenyl carbamate P2 prime group. [electronic resource] by Corte, James R Fang, Tianan Pinto, Donald J P Orwat, Michael J Rendina, Alan R Luettgen, Joseph M Rossi, Karen A Wei, Anzhi Ramamurthy, Vidhyashankar Myers, Joseph E Sheriff, Steven Narayanan, Rangaraj Harper, Timothy W Zheng, Joanna J Li, Yi-Xin Seiffert, Dietmar A Wexler, Ruth R Quan, Mimi L Producer: 20170705 In: Bioorganic & medicinal chemistry vol. 24 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	22.	Discovery of potent, efficacious, and orally bioavailable inhibitors of blood coagulation factor Xa with neutral P1 moieties. [electronic resource] by Pinto, Donald J P Galemmo, Robert A Quan, Mimi L Orwat, Michael J Clark, Charles Li, Renhua Wells, Brian Woerner, Francis Alexander, Richard S Rossi, Karen A Smallwood, Angela Wong, Pancras C Luettgen, Joseph M Rendina, Alan R Knabb, Robert M He, Kan Wexler, Ruth R Lam, Patrick Y S Producer: 20061222 In: Bioorganic & medicinal chemistry letters vol. 16 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	23.	Discovery of 1-(2-aminomethylphenyl)-3-trifluoromethyl-N- [3-fluoro-2'-(aminosulfonyl)[1,1'-biphenyl)]-4-yl]-1H-pyrazole-5-carboxyamide (DPC602), a potent, selective, and orally bioavailable factor Xa inhibitor(1). [electronic resource] by Pruitt, James R Pinto, Donald J P Galemmo, Robert A Alexander, Richard S Rossi, Karen A Wells, Brian L Drummond, Spencer Bostrom, Lori L Burdick, Debra Bruckner, Robert Chen, Haiying Smallwood, Angela Wong, Pancras C Wright, Matthew R Bai, Steven Luettgen, Joseph M Knabb, Robert M Lam, Patrick Y S Wexler, Ruth R Producer: 20040116 In: Journal of medicinal chemistry vol. 46 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	24.	Structure-based design of novel guanidine/benzamidine mimics: potent and orally bioavailable factor Xa inhibitors as novel anticoagulants. [electronic resource] by Lam, Patrick Y S Clark, Charles G Li, Renhua Pinto, Donald J P Orwat, Michael J Galemmo, Robert A Fevig, John M Teleha, Christopher A Alexander, Richard S Smallwood, Angela M Rossi, Karen A Wright, Matthew R Bai, Stephen A He, Kan Luettgen, Joseph M Wong, Pancras C Knabb, Robert M Wexler, Ruth R Producer: 20031112 In: Journal of medicinal chemistry vol. 46 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	25.	1-[3-Aminobenzisoxazol-5'-yl]-3-trifluoromethyl-6-[2'-(3-(R)-hydroxy-N-pyrrolidinyl)methyl-[1,1']-biphen-4-yl]-1,4,5,6-tetrahydropyrazolo-[3,4-c]-pyridin-7-one (BMS-740808) a highly potent, selective, efficacious, and orally bioavailable inhibitor of blood coagulation factor Xa. [electronic resource] by Pinto, Donald J P Orwat, Michael J Quan, Mimi L Han, Qi Galemmo, Robert A Amparo, Eugene Wells, Brian Ellis, Christopher He, Ming Y Alexander, Richard S Rossi, Karen A Smallwood, Angela Wong, Pancras C Luettgen, Joseph M Rendina, Alan R Knabb, Robert M Mersinger, Lawrence Kettner, Charles Bai, Steven He, Kan Wexler, Ruth R Lam, Patrick Y S Producer: 20060911 In: Bioorganic & medicinal chemistry letters vol. 16 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	26.	Structure-based design of inhibitors of coagulation factor XIa with novel P1 moieties. [electronic resource] by Pinto, Donald J P Smallheer, Joanne M Corte, James R Austin, Erin J D Wang, Cailan Fang, Tianan Smith, Leon M Rossi, Karen A Rendina, Alan R Bozarth, Jeffrey M Zhang, Ge Wei, Anzhi Ramamurthy, Vidhyashankar Sheriff, Steven Myers, Joseph E Morin, Paul E Luettgen, Joseph M Seiffert, Dietmar A Quan, Mimi L Wexler, Ruth R Producer: 20151221 In: Bioorganic & medicinal chemistry letters vol. 25 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	27.	Structure-activity relationships of anthranilamide-based factor Xa inhibitors containing piperidinone and pyridinone P4 moieties. [electronic resource] by Corte, James R Fang, Tianan Pinto, Donald J P Han, Wei Hu, Zilun Jiang, Xiang-Jun Li, Yun-Long Gauuan, Jolicia F Hadden, Mark Orton, Darren Rendina, Alan R Luettgen, Joseph M Wong, Pancras C He, Kan Morin, Paul E Chang, Chong-Hwan Cheney, Daniel L Knabb, Robert M Wexler, Ruth R Lam, Patrick Y S Producer: 20080715 In: Bioorganic & medicinal chemistry letters vol. 18 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	28.	N-in-1 dosing pharmacokinetics in drug discovery: experience, theoretical and practical considerations. [electronic resource] by He, Kan Qian, Mingxin Wong, Harvey Bai, Stephen A He, Bing Brogdon, Bernice Grace, James E Xin, Baomin Wu, Jingtao Ren, Shelly X Zeng, Hang Deng, Yuzhong Graden, Danielle M Olah, Timothy V Unger, Steve E Luettgen, Joseph M Knabb, Robert M Pinto, Donald J Lam, Patrick Y S Duan, James Wexler, Ruth R Decicco, Carl P Christ, David D Grossman, Scott J Producer: 20081009 In: Journal of pharmaceutical sciences vol. 97 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	29.	Novel phenylalanine derived diamides as Factor XIa inhibitors. [electronic resource] by Smith, Leon M Orwat, Michael J Hu, Zilun Han, Wei Wang, Cailan Rossi, Karen A Gilligan, Paul J Pabbisetty, Kumar B Osuna, Honey Corte, James R Rendina, Alan R Luettgen, Joseph M Wong, Pancras C Narayanan, Ranga Harper, Timothy W Bozarth, Jeffrey M Crain, Earl J Wei, Anzhi Ramamurthy, Vidhyashankar Morin, Paul E Xin, Baomin Zheng, Joanna Seiffert, Dietmar A Quan, Mimi L Lam, Patrick Y S Wexler, Ruth R Pinto, Donald J P Producer: 20170116 In: Bioorganic & medicinal chemistry letters vol. 26 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	30.	Structure based design of macrocyclic factor XIa inhibitors: Discovery of cyclic P1 linker moieties with improved oral bioavailability. [electronic resource] by Clark, Charles G Rossi, Karen A Corte, James R Fang, Tianan Smallheer, Joanne M De Lucca, Indawati Nirschl, David S Orwat, Michael J Pinto, Donald J P Hu, Zilun Wang, Yufeng Yang, Wu Jeon, Yoon Ewing, William R Myers, Joseph E Sheriff, Steven Lou, Zhen Bozarth, Jeffrey M Wu, Yiming Rendina, Alan Harper, Timothy Zheng, Joanna Xin, Baomin Xiang, Qian Luettgen, Joseph M Seiffert, Dietmar A Wexler, Ruth R Lam, Patrick Y S Producer: 20200921 In: Bioorganic & medicinal chemistry letters vol. 29 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	31.	Discovery of a Parenteral Small Molecule Coagulation Factor XIa Inhibitor Clinical Candidate (BMS-962212). [electronic resource] by Pinto, Donald J P Orwat, Michael J Smith, Leon M Quan, Mimi L Lam, Patrick Y S Rossi, Karen A Apedo, Atsu Bozarth, Jeffrey M Wu, Yiming Zheng, Joanna J Xin, Baomin Toussaint, Nathalie Stetsko, Paul Gudmundsson, Olafur Maxwell, Brad Crain, Earl J Wong, Pancras C Lou, Zhen Harper, Timothy W Chacko, Silvi A Myers, Joseph E Sheriff, Steven Zhang, Huiping Hou, Xiaoping Mathur, Arvind Seiffert, Dietmar A Wexler, Ruth R Luettgen, Joseph M Ewing, William R Producer: 20171229 In: Journal of medicinal chemistry vol. 60 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	32.	Potent, Orally Bioavailable, and Efficacious Macrocyclic Inhibitors of Factor XIa. Discovery of Pyridine-Based Macrocycles Possessing Phenylazole Carboxamide P1 Groups. [electronic resource] by Corte, James R Pinto, Donald J P Fang, Tianan Osuna, Honey Yang, Wu Wang, Yufeng Lai, Amy Clark, Charles G Sun, Jung-Hui Rampulla, Richard Mathur, Arvind Kaspady, Mahammed Neithnadka, Premsai Rai Li, Yi-Xin Cindy Rossi, Karen A Myers, Joseph E Sheriff, Steven Lou, Zhen Harper, Timothy W Huang, Christine Zheng, Joanna J Bozarth, Jeffrey M Wu, Yiming Wong, Pancras C Crain, Earl J Seiffert, Dietmar A Luettgen, Joseph M Lam, Patrick Y S Wexler, Ruth R Ewing, William R Producer: 20200727 In: Journal of medicinal chemistry vol. 63 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)