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21.
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Exacerbation of cerebral amyloid angiopathy-associated microhemorrhage in amyloid precursor protein transgenic mice by immunotherapy is dependent on antibody recognition of deposited forms of amyloid beta. [electronic resource] by
- Racke, Margaret M
- Boone, Laura I
- Hepburn, Deena L
- Parsadainian, Maia
- Bryan, Matthew T
- Ness, Daniel K
- Piroozi, Kathy S
- Jordan, William H
- Brown, Donna D
- Hoffman, Wherly P
- Holtzman, David M
- Bales, Kelly R
- Gitter, Bruce D
- May, Patrick C
- Paul, Steven M
- DeMattos, Ronald B
Producer: 20050818
In:
The Journal of neuroscience : the official journal of the Society for Neuroscience vol. 25
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22.
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Safety and Tolerability of Multiple Ascending Doses of PRX002/RG7935, an Anti-α-Synuclein Monoclonal Antibody, in Patients With Parkinson Disease: A Randomized Clinical Trial. [electronic resource] by
- Jankovic, Joseph
- Goodman, Ira
- Safirstein, Beth
- Marmon, Tonya K
- Schenk, Dale B
- Koller, Martin
- Zago, Wagner
- Ness, Daniel K
- Griffith, Sue G
- Grundman, Michael
- Soto, Jay
- Ostrowitzki, Susanne
- Boess, Frank G
- Martin-Facklam, Meret
- Quinn, Joseph F
- Isaacson, Stuart H
- Omidvar, Omid
- Ellenbogen, Aaron
- Kinney, Gene G
Producer: 20191008
In:
JAMA neurology vol. 75
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23.
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Discovery of a novel [3.2.1] benzo fused bicyclic sulfonamide-pyrazoles as potent, selective and efficacious γ-secretase inhibitors. [electronic resource] by
- Ye, Xiaocong M
- Konradi, Andrei W
- Sun, Minghua
- Yuan, Shendong
- Aubele, Danielle L
- Dappen, Michael
- Dressen, Darren
- Garofalo, Albert W
- Jagodzinski, Jacek J
- Latimer, Lee
- Probst, Gary D
- Sham, Hing L
- Wone, David
- Xu, Ying-zi
- Ness, Daniel
- Brigham, Elizabeth
- Kwong, Grace T
- Willtis, Chris
- Tonn, George
- Goldbach, Erich
- Quinn, Kevin P
- Zhang, Hongbin H
- Sauer, John-Michael
- Bova, Michael
- Basi, Guriqbal S
Producer: 20131031
In:
Bioorganic & medicinal chemistry letters vol. 23
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24.
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A rationale for determining, testing, and controlling specific impurities in pharmaceuticals that possess potential for genotoxicity. [electronic resource] by
- Müller, Lutz
- Mauthe, Robert J
- Riley, Christopher M
- Andino, Marta M
- Antonis, David De
- Beels, Chris
- DeGeorge, Joseph
- De Knaep, Alfons G M
- Ellison, Dean
- Fagerland, Jane A
- Frank, Rebecca
- Fritschel, Betsy
- Galloway, Sheila
- Harpur, Ernie
- Humfrey, Charles D N
- Jacks, Alexander S
- Jagota, Nirdosh
- Mackinnon, John
- Mohan, Ganapathy
- Ness, Daniel K
- O'Donovan, Michael R
- Smith, Mark D
- Vudathala, Gopi
- Yotti, Larry
Producer: 20070614
In:
Regulatory toxicology and pharmacology : RTP vol. 44
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25.
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Amyloid precursor protein selective gamma-secretase inhibitors for treatment of Alzheimer's disease. [electronic resource] by
- Basi, Guriqbal S
- Hemphill, Susanna
- Brigham, Elizabeth F
- Liao, Anna
- Aubele, Danielle L
- Baker, Jeanne
- Barbour, Robin
- Bova, Michael
- Chen, Xiao-Hua
- Dappen, Michael S
- Eichenbaum, Tovah
- Goldbach, Erich
- Hawkinson, Jon
- Lawler-Herbold, Rose
- Hu, Kang
- Hui, Terence
- Jagodzinski, Jacek J
- Keim, Pamela S
- Kholodenko, Dora
- Latimer, Lee H
- Lee, Mike
- Marugg, Jennifer
- Mattson, Matthew N
- McCauley, Scott
- Miller, James L
- Motter, Ruth
- Mutter, Linda
- Neitzel, Martin L
- Ni, Huifang
- Nguyen, Lan
- Quinn, Kevin
- Ruslim, Lany
- Semko, Christopher M
- Shapiro, Paul
- Smith, Jenifer
- Soriano, Ferdie
- Szoke, Balazs
- Tanaka, Kevin
- Tang, Pearl
- Tucker, John A
- Ye, Xiacong Michael
- Yu, Mei
- Wu, Jing
- Xu, Ying-Zi
- Garofalo, Albert W
- Sauer, John Michael
- Konradi, Andrei W
- Ness, Daniel
- Shopp, George
- Pleiss, Michael A
- Freedman, Stephen B
- Schenk, Dale
Producer: 20110714
In:
Alzheimer's research & therapy vol. 2
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26.
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Discovery of (R)-4-cyclopropyl-7,8-difluoro-5-(4-(trifluoromethyl)phenylsulfonyl)-4,5-dihydro-1H-pyrazolo[4,3-c]quinoline (ELND006) and (R)-4-cyclopropyl-8-fluoro-5-(6-(trifluoromethyl)pyridin-3-ylsulfonyl)-4,5-dihydro-2H-pyrazolo[4,3-c]quinoline (ELND007): metabolically stable γ-secretase Inhibitors that selectively inhibit the production of amyloid-β over Notch. [electronic resource] by
- Probst, Gary
- Aubele, Danielle L
- Bowers, Simeon
- Dressen, Darren
- Garofalo, Albert W
- Hom, Roy K
- Konradi, Andrei W
- Marugg, Jennifer L
- Mattson, Matthew N
- Neitzel, Martin L
- Semko, Chris M
- Sham, Hing L
- Smith, Jenifer
- Sun, Minghua
- Truong, Anh P
- Ye, Xiaocong M
- Xu, Ying-Zi
- Dappen, Michael S
- Jagodzinski, Jacek J
- Keim, Pamela S
- Peterson, Brian
- Latimer, Lee H
- Quincy, David
- Wu, Jing
- Goldbach, Erich
- Ness, Daniel K
- Quinn, Kevin P
- Sauer, John-Michael
- Wong, Karina
- Zhang, Hongbin
- Zmolek, Wes
- Brigham, Elizabeth F
- Kholodenko, Dora
- Hu, Kang
- Kwong, Grace T
- Lee, Michael
- Liao, Anna
- Motter, Ruth N
- Sacayon, Patricia
- Santiago, Pamela
- Willits, Christopher
- Bard, Frédérique
- Bova, Michael P
- Hemphill, Susanna S
- Nguyen, Lam
- Ruslim, Lany
- Tanaka, Kevin
- Tanaka, Pearl
- Wallace, William
- Yednock, Ted A
- Basi, Guriqbal S
Producer: 20140310
In:
Journal of medicinal chemistry vol. 56
Availability: No items available.
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