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Enzastaurin plus temozolomide with radiation therapy in glioblastoma multiforme: a phase I study. [electronic resource] by
- Butowski, Nicholas
- Chang, Susan M
- Lamborn, Kathleen R
- Polley, Mei Yin
- Parvataneni, R
- Hristova-Kazmierski, Maria
- Musib, Luna
- Nicol, Steven J
- Thornton, Donald E
- Prados, Michael D
Producer: 20110222
In:
Neuro-oncology vol. 12
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Development and validation of a drug activity biomarker that shows target inhibition in cancer patients receiving enzastaurin, a novel protein kinase C-beta inhibitor. [electronic resource] by
- Green, Lisa J
- Marder, Philip
- Ray, Chad
- Cook, Carolyn A
- Jaken, Susan
- Musib, Luna C
- Herbst, Roy S
- Carducci, Michael
- Britten, Carolyn D
- Basche, Michele
- Eckhardt, S Gail
- Thornton, Donald
Producer: 20071109
In:
Clinical cancer research : an official journal of the American Association for Cancer Research vol. 12
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24.
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Absorption, Metabolism, Excretion, and the Contribution of Intestinal Metabolism to the Oral Disposition of [14C]Cobimetinib, a MEK Inhibitor, in Humans. [electronic resource] by
- Takahashi, Ryan H
- Choo, Edna F
- Ma, Shuguang
- Wong, Susan
- Halladay, Jason
- Deng, Yuzhong
- Rooney, Isabelle
- Gates, Mary
- Hop, Cornelis E C A
- Khojasteh, S Cyrus
- Dresser, Mark J
- Musib, Luna
Producer: 20160913
In:
Drug metabolism and disposition: the biological fate of chemicals vol. 44
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A phase I safety, tolerability, and pharmacokinetic study of enzastaurin combined with capecitabine in patients with advanced solid tumors. [electronic resource] by
- Camidge, D Ross
- Gail Eckhardt, S
- Gore, Lia
- O'Bryant, Cindy L
- Leong, Stephen
- Basche, Michelle
- Holden, Scott N
- Musib, Luna
- Baldwin, John
- Darstein, Christelle
- Thornton, Donald
- Finn, Richard S
- Britten, Carolyn D
Producer: 20080123
In:
Anti-cancer drugs vol. 19
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26.
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Phase I dose escalation and pharmacokinetic study of enzastaurin, an oral protein kinase C beta inhibitor, in patients with advanced cancer. [electronic resource] by
- Carducci, Michael A
- Musib, Luna
- Kies, Merrill S
- Pili, Roberto
- Truong, Mylene
- Brahmer, Julie R
- Cole, Patricia
- Sullivan, Rana
- Riddle, Jeanne
- Schmidt, Jill
- Enas, Nathan
- Sinha, Vikram
- Thornton, Donald E
- Herbst, Roy S
Producer: 20060918
In:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology vol. 24
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Phase III study of enzastaurin compared with lomustine in the treatment of recurrent intracranial glioblastoma. [electronic resource] by
- Wick, Wolfgang
- Puduvalli, Vinay K
- Chamberlain, Marc C
- van den Bent, Martin J
- Carpentier, Antoine F
- Cher, Lawrence M
- Mason, Warren
- Weller, Michael
- Hong, Shengyan
- Musib, Luna
- Liepa, Astra M
- Thornton, Donald E
- Fine, Howard A
Producer: 20100325
In:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology vol. 28
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28.
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Combination of vemurafenib and cobimetinib in patients with advanced BRAF(V600)-mutated melanoma: a phase 1b study. [electronic resource] by
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- Gonzalez, Rene
- Pavlick, Anna
- Hamid, Omid
- Gajewski, Thomas F
- Daud, Adil
- Flaherty, Lawrence
- Logan, Theodore
- Chmielowski, Bartosz
- Lewis, Karl
- Kee, Damien
- Boasberg, Peter
- Yin, Ming
- Chan, Iris
- Musib, Luna
- Choong, Nicholas
- Puzanov, Igor
- McArthur, Grant A
Producer: 20141215
In:
The Lancet. Oncology vol. 15
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29.
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Phase I pharmacokinetic and pharmacodynamic study of the oral protein kinase C beta-inhibitor enzastaurin in combination with gemcitabine and cisplatin in patients with advanced cancer. [electronic resource] by
- Rademaker-Lakhai, Jeany M
- Beerepoot, Laurens V
- Mehra, Niven
- Radema, Sandra A
- van Maanen, Rianne
- Vermaat, Joost S
- Witteveen, Els O
- Visseren-Grul, Carla M
- Musib, Luna
- Enas, Nathan
- van Hal, Gertjan
- Beijnen, Jos H
- Schellens, Jan H M
- Voest, Emile E
Producer: 20071026
In:
Clinical cancer research : an official journal of the American Association for Cancer Research vol. 13
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30.
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Phase Ib study of the MEK inhibitor cobimetinib (GDC-0973) in combination with the PI3K inhibitor pictilisib (GDC-0941) in patients with advanced solid tumors. [electronic resource] by
- Shapiro, Geoffrey I
- LoRusso, Patricia
- Kwak, Eunice
- Pandya, Susan
- Rudin, Charles M
- Kurkjian, Carla
- Cleary, James M
- Pilat, Mary Jo
- Jones, Suzanne
- de Crespigny, Alex
- Fredrickson, Jill
- Musib, Luna
- Yan, Yibing
- Wongchenko, Matthew
- Hsieh, Hsin-Ju
- Gates, Mary R
- Chan, Iris T
- Bendell, Johanna
Producer: 20210303
In:
Investigational new drugs vol. 38
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A First-in-Human Phase I Study of the ATP-Competitive AKT Inhibitor Ipatasertib Demonstrates Robust and Safe Targeting of AKT in Patients with Solid Tumors. [electronic resource] by
- Saura, Cristina
- Roda, Desamparados
- Roselló, Susana
- Oliveira, Mafalda
- Macarulla, Teresa
- Pérez-Fidalgo, José Alejandro
- Morales-Barrera, Rafael
- Sanchis-García, Juan Manuel
- Musib, Luna
- Budha, Nageshwar
- Zhu, Jin
- Nannini, Michelle
- Chan, Wai Y
- Sanabria Bohórquez, Sandra M
- Meng, Raymond D
- Lin, Kui
- Yan, Yibing
- Patel, Premal
- Baselga, José
- Tabernero, Josep
- Cervantes, Andrés
Producer: 20171102
In:
Cancer discovery vol. 7
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32.
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The protein kinase Cbeta-selective inhibitor, Enzastaurin (LY317615.HCl), suppresses signaling through the AKT pathway, induces apoptosis, and suppresses growth of human colon cancer and glioblastoma xenografts. [electronic resource] by
- Graff, Jeremy R
- McNulty, Ann M
- Hanna, Kimberly Ross
- Konicek, Bruce W
- Lynch, Rebecca L
- Bailey, Spring N
- Banks, Crystal
- Capen, Andrew
- Goode, Robin
- Lewis, Jason E
- Sams, Lillian
- Huss, Karen L
- Campbell, Robert M
- Iversen, Philip W
- Neubauer, Blake Lee
- Brown, Thomas J
- Musib, Luna
- Geeganage, Sandaruwan
- Thornton, Donald
Producer: 20051027
In:
Cancer research vol. 65
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33.
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Phase II study of enzastaurin, a protein kinase C beta inhibitor, in patients with relapsed or refractory diffuse large B-cell lymphoma. [electronic resource] by
- Robertson, Michael J
- Kahl, Brad S
- Vose, Julie M
- de Vos, Sven
- Laughlin, Mary
- Flynn, Patrick J
- Rowland, Kendrith
- Cruz, Jose C
- Goldberg, Stuart L
- Musib, Luna
- Darstein, Christelle
- Enas, Nathan
- Kutok, Jeffery L
- Aster, Jon C
- Neuberg, Donna
- Savage, Kerry J
- LaCasce, Ann
- Thornton, Donald
- Slapak, Christopher A
- Shipp, Margaret A
Producer: 20070525
In:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology vol. 25
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34.
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Association of body-mass index and outcomes in patients with metastatic melanoma treated with targeted therapy, immunotherapy, or chemotherapy: a retrospective, multicohort analysis. [electronic resource] by
- McQuade, Jennifer L
- Daniel, Carrie R
- Hess, Kenneth R
- Mak, Carmen
- Wang, Daniel Y
- Rai, Rajat R
- Park, John J
- Haydu, Lauren E
- Spencer, Christine
- Wongchenko, Matthew
- Lane, Stephen
- Lee, Dung-Yang
- Kaper, Mathilde
- McKean, Meredith
- Beckermann, Kathryn E
- Rubinstein, Samuel M
- Rooney, Isabelle
- Musib, Luna
- Budha, Nageshwar
- Hsu, Jessie
- Nowicki, Theodore S
- Avila, Alexandre
- Haas, Tomas
- Puligandla, Maneka
- Lee, Sandra
- Fang, Shenying
- Wargo, Jennifer A
- Gershenwald, Jeffrey E
- Lee, Jeffrey E
- Hwu, Patrick
- Chapman, Paul B
- Sosman, Jeffrey A
- Schadendorf, Dirk
- Grob, Jean-Jacques
- Flaherty, Keith T
- Walker, Dana
- Yan, Yibing
- McKenna, Edward
- Legos, Jeffrey J
- Carlino, Matteo S
- Ribas, Antoni
- Kirkwood, John M
- Long, Georgina V
- Johnson, Douglas B
- Menzies, Alexander M
- Davies, Michael A
Producer: 20190226
In:
The Lancet. Oncology vol. 19
Availability: No items available.
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