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21.
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Antiviral and pharmacokinetic properties of C2 symmetric inhibitors of the human immunodeficiency virus type 1 protease. [electronic resource] by
- Kempf, D J
- Marsh, K C
- Paul, D A
- Knigge, M F
- Norbeck, D W
- Kohlbrenner, W E
- Codacovi, L
- Vasavanonda, S
- Bryant, P
- Wang, X C
Producer: 19920424
In:
Antimicrobial agents and chemotherapy vol. 35
Availability: No items available.
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22.
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Identification of genotypic changes in human immunodeficiency virus protease that correlate with reduced susceptibility to the protease inhibitor lopinavir among viral isolates from protease inhibitor-experienced patients. [electronic resource] by
- Kempf, D J
- Isaacson, J D
- King, M S
- Brun, S C
- Xu, Y
- Real, K
- Bernstein, B M
- Japour, A J
- Sun, E
- Rode, R A
Producer: 20010823
In:
Journal of virology vol. 75
Availability: No items available.
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23.
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ABT-538 is a potent inhibitor of human immunodeficiency virus protease and has high oral bioavailability in humans. [electronic resource] by
- Kempf, D J
- Marsh, K C
- Denissen, J F
- McDonald, E
- Vasavanonda, S
- Flentge, C A
- Green, B E
- Fino, L
- Park, C H
- Kong, X P
Producer: 19950511
In:
Proceedings of the National Academy of Sciences of the United States of America vol. 92
Availability: No items available.
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24.
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Structure-based, C2 symmetric inhibitors of HIV protease. [electronic resource] by
- Kempf, D J
- Norbeck, D W
- Codacovi, L
- Wang, X C
- Kohlbrenner, W E
- Wideburg, N E
- Paul, D A
- Knigge, M F
- Vasavanonda, S
- Craig-Kennard, A
Producer: 19901120
In:
Journal of medicinal chemistry vol. 33
Availability: No items available.
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25.
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The duration of viral suppression during protease inhibitor therapy for HIV-1 infection is predicted by plasma HIV-1 RNA at the nadir. [electronic resource] by
- Kempf, D J
- Rode, R A
- Xu, Y
- Sun, E
- Heath-Chiozzi, M E
- Valdes, J
- Japour, A J
- Danner, S
- Boucher, C
- Molla, A
- Leonard, J M
Producer: 19980608
In:
AIDS (London, England) vol. 12
Availability: No items available.
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26.
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Potent HIV-1 protease inhibitors with antiviral activities in vitro. [electronic resource] by
- Sham, H L
- Betebenner, D A
- Wideburg, N E
- Saldivar, A C
- Kohlbrenner, W E
- Vasavanonda, S
- Kempf, D J
- Norbeck, D W
- Zhao, C
- Clement, J J
Producer: 19910605
In:
Biochemical and biophysical research communications vol. 175
Availability: No items available.
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27.
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Selection of multiple human immunodeficiency virus type 1 variants that encode viral proteases with decreased sensitivity to an inhibitor of the viral protease. [electronic resource] by
- Kaplan, A H
- Michael, S F
- Wehbie, R S
- Knigge, M F
- Paul, D A
- Everitt, L
- Kempf, D J
- Norbeck, D W
- Erickson, J W
- Swanstrom, R
Producer: 19940706
In:
Proceedings of the National Academy of Sciences of the United States of America vol. 91
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28.
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Pseudo-symmetrical difluoroketones. Highly potent and specific inhibitors of HIV-1 protease. [electronic resource] by
- Sham, H L
- Betebenner, D A
- Wideburg, N
- Saldivar, A C
- Kohlbrenner, W E
- Craig-Kennard, A
- Vasavanonda, S
- Kempf, D J
- Clement, J J
- Erickson, J E
Producer: 19930921
In:
FEBS letters vol. 329
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29.
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Potent, low molecular weight renin inhibitors containing a C-terminal heterocycle: hydrogen bonding at the active site. [electronic resource] by
- Rosenberg, S H
- Dellaria, J F
- Kempf, D J
- Hutchins, C W
- Woods, K W
- Maki, R G
- de Lara, E
- Spina, K P
- Stein, H H
- Cohen, J
Producer: 19900628
In:
Journal of medicinal chemistry vol. 33
Availability: No items available.
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30.
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In vitro metabolism of the HIV-1 protease inhibitor ABT-378: species comparison and metabolite identification. [electronic resource] by
- Kumar, G N
- Jayanti, V
- Lee, R D
- Whittern, D N
- Uchic, J
- Thomas, S
- Johnson, P
- Grabowski, B
- Sham, H
- Betebenner, D
- Kempf, D J
- Denissen, J F
Producer: 19990301
In:
Drug metabolism and disposition: the biological fate of chemicals vol. 27
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31.
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Human serum attenuates the activity of protease inhibitors toward wild-type and mutant human immunodeficiency virus. [electronic resource] by
- Molla, A
- Vasavanonda, S
- Kumar, G
- Sham, H L
- Johnson, M
- Grabowski, B
- Denissen, J F
- Kohlbrenner, W
- Plattner, J J
- Leonard, J M
- Norbeck, D W
- Kempf, D J
Producer: 19981217
In:
Virology vol. 250
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32.
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Potent piperazine hydroxyethylamine HIV protease inhibitors containing novel P3 ligands. [electronic resource] by
- Chen, X
- Kempf, D J
- Sham, H L
- Green, B E
- Molla, A
- Korneyeva, M
- Vasavanonda, S
- Wideburg, N E
- Saldivar, A
- Marsh, K C
- McDonald, E
- Norbeck, D W
Producer: 19990405
In:
Bioorganic & medicinal chemistry letters vol. 8
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33.
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NMR-based discovery of lead inhibitors that block DNA binding of the human papillomavirus E2 protein. [electronic resource] by
- Hajduk, P J
- Dinges, J
- Miknis, G F
- Merlock, M
- Middleton, T
- Kempf, D J
- Egan, D A
- Walter, K A
- Robins, T S
- Shuker, S B
- Holzman, T F
- Fesik, S W
Producer: 19971110
In:
Journal of medicinal chemistry vol. 40
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34.
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Pharmacokinetic enhancement of inhibitors of the human immunodeficiency virus protease by coadministration with ritonavir. [electronic resource] by
- Kempf, D J
- Marsh, K C
- Kumar, G
- Rodrigues, A D
- Denissen, J F
- McDonald, E
- Kukulka, M J
- Hsu, A
- Granneman, G R
- Baroldi, P A
- Sun, E
- Pizzuti, D
- Plattner, J J
- Norbeck, D W
- Leonard, J M
Producer: 19970602
In:
Antimicrobial agents and chemotherapy vol. 41
Availability: No items available.
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35.
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Ordered accumulation of mutations in HIV protease confers resistance to ritonavir. [electronic resource] by
- Molla, A
- Korneyeva, M
- Gao, Q
- Vasavanonda, S
- Schipper, P J
- Mo, H M
- Markowitz, M
- Chernyavskiy, T
- Niu, P
- Lyons, N
- Hsu, A
- Granneman, G R
- Ho, D D
- Boucher, C A
- Leonard, J M
- Norbeck, D W
- Kempf, D J
Producer: 19960813
In:
Nature medicine vol. 2
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36.
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Ritonavir and saquinavir combination therapy for the treatment of HIV infection. [electronic resource] by
- Cameron, D W
- Japour, A J
- Xu, Y
- Hsu, A
- Mellors, J
- Farthing, C
- Cohen, C
- Poretz, D
- Markowitz, M
- Follansbee, S
- Angel, J B
- McMahon, D
- Ho, D
- Devanarayan, V
- Rode, R
- Salgo, M
- Kempf, D J
- Granneman, R
- Leonard, J M
- Sun, E
Producer: 19990528
In:
AIDS (London, England) vol. 13
Availability: No items available.
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37.
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Discovery of ritonavir, a potent inhibitor of HIV protease with high oral bioavailability and clinical efficacy. [electronic resource] by
- Kempf, D J
- Sham, H L
- Marsh, K C
- Flentge, C A
- Betebenner, D
- Green, B E
- McDonald, E
- Vasavanonda, S
- Saldivar, A
- Wideburg, N E
- Kati, W M
- Ruiz, L
- Zhao, C
- Fino, L
- Patterson, J
- Molla, A
- Plattner, J J
- Norbeck, D W
Producer: 19980317
In:
Journal of medicinal chemistry vol. 41
Availability: No items available.
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38.
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A novel, picomolar inhibitor of human immunodeficiency virus type 1 protease. [electronic resource] by
- Sham, H L
- Zhao, C
- Stewart, K D
- Betebenner, D A
- Lin, S
- Park, C H
- Kong, X P
- Rosenbrook, W
- Herrin, T
- Madigan, D
- Vasavanonda, S
- Lyons, N
- Molla, A
- Saldivar, A
- Marsh, K C
- McDonald, E
- Wideburg, N E
- Denissen, J F
- Robins, T
- Kempf, D J
- Plattner, J J
- Norbeck, D W
Producer: 19960228
In:
Journal of medicinal chemistry vol. 39
Availability: No items available.
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39.
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ABT-378, a highly potent inhibitor of the human immunodeficiency virus protease. [electronic resource] by
- Sham, H L
- Kempf, D J
- Molla, A
- Marsh, K C
- Kumar, G N
- Chen, C M
- Kati, W
- Stewart, K
- Lal, R
- Hsu, A
- Betebenner, D
- Korneyeva, M
- Vasavanonda, S
- McDonald, E
- Saldivar, A
- Wideburg, N
- Chen, X
- Niu, P
- Park, C
- Jayanti, V
- Grabowski, B
- Granneman, G R
- Sun, E
- Japour, A J
- Leonard, J M
- Plattner, J J
- Norbeck, D W
Producer: 19990222
In:
Antimicrobial agents and chemotherapy vol. 42
Availability: No items available.
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