Results
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21.
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Positive Allosteric Modulators of GluN2A-Containing NMDARs with Distinct Modes of Action and Impacts on Circuit Function. [electronic resource] by
- Hackos, David H
- Lupardus, Patrick J
- Grand, Teddy
- Chen, Yelin
- Wang, Tzu-Ming
- Reynen, Paul
- Gustafson, Amy
- Wallweber, Heidi J A
- Volgraf, Matthew
- Sellers, Benjamin D
- Schwarz, Jacob B
- Paoletti, Pierre
- Sheng, Morgan
- Zhou, Qiang
- Hanson, Jesse E
Producer: 20160713
In:
Neuron vol. 89
Availability: No items available.
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22.
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TRPA1 modulation by piperidine carboxamides suggests an evolutionarily conserved binding site and gating mechanism. [electronic resource] by
- Chernov-Rogan, Tania
- Gianti, Eleonora
- Liu, Chang
- Villemure, Elisia
- Cridland, Andrew P
- Hu, Xiaoyu
- Ballini, Elisa
- Lange, Wienke
- Deisemann, Heike
- Li, Tianbo
- Ward, Stuart I
- Hackos, David H
- Magnuson, Steven
- Safina, Brian
- Klein, Michael L
- Volgraf, Matthew
- Carnevale, Vincenzo
- Chen, Jun
Producer: 20200401
In:
Proceedings of the National Academy of Sciences of the United States of America vol. 116
Availability: No items available.
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23.
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Structural basis of α-scorpion toxin action on Na [electronic resource] by
- Clairfeuille, Thomas
- Cloake, Alexander
- Infield, Daniel T
- Llongueras, José P
- Arthur, Christopher P
- Li, Zhong Rong
- Jian, Yuwen
- Martin-Eauclaire, Marie-France
- Bougis, Pierre E
- Ciferri, Claudio
- Ahern, Christopher A
- Bosmans, Frank
- Hackos, David H
- Rohou, Alexis
- Payandeh, Jian
Producer: 20190823
In:
Science (New York, N.Y.) vol. 363
Availability: No items available.
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24.
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GluN2A-Selective Pyridopyrimidinone Series of NMDAR Positive Allosteric Modulators with an Improved [electronic resource] by
- Villemure, Elisia
- Volgraf, Matthew
- Jiang, Yu
- Wu, Guosheng
- Ly, Cuong Q
- Yuen, Po-Wai
- Lu, Aijun
- Luo, Xifeng
- Liu, Mingcui
- Zhang, Shun
- Lupardus, Patrick J
- Wallweber, Heidi J A
- Liederer, Bianca M
- Deshmukh, Gauri
- Plise, Emile
- Tay, Suzanne
- Wang, Tzu-Ming
- Hanson, Jesse E
- Hackos, David H
- Scearce-Levie, Kimberly
- Schwarz, Jacob B
- Sellers, Benjamin D
Publication details: ACS medicinal chemistry letters Jan 2017
In:
ACS medicinal chemistry letters vol. 8
Availability: No items available.
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25.
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Selective Na [electronic resource] by
- Bankar, Girish
- Goodchild, Samuel J
- Howard, Sarah
- Nelkenbrecher, Karen
- Waldbrook, Matthew
- Dourado, Michelle
- Shuart, Noah G
- Lin, Sophia
- Young, Clint
- Xie, Zhiwei
- Khakh, Kuldip
- Chang, Elaine
- Sojo, Luis E
- Lindgren, Andrea
- Chowdhury, Sultan
- Decker, Shannon
- Grimwood, Michael
- Andrez, Jean-Christophe
- Dehnhardt, Christoph M
- Pang, Jodie
- Chang, Jae H
- Safina, Brian S
- Sutherlin, Daniel P
- Johnson, James P
- Hackos, David H
- Robinette, C Lee
- Cohen, Charles J
Producer: 20191209
In:
Cell reports vol. 24
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26.
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GluN2A NMDA Receptor Enhancement Improves Brain Oscillations, Synchrony, and Cognitive Functions in Dravet Syndrome and Alzheimer's Disease Models. [electronic resource] by
- Hanson, Jesse E
- Ma, Keran
- Elstrott, Justin
- Weber, Martin
- Saillet, Sandrine
- Khan, Abdullah S
- Simms, Jeffrey
- Liu, Benjamin
- Kim, Thomas A
- Yu, Gui-Qiu
- Chen, Yelin
- Wang, Tzu-Ming
- Jiang, Zhiyu
- Liederer, Bianca M
- Deshmukh, Gauri
- Solanoy, Hilda
- Chan, Connie
- Sellers, Benjamin D
- Volgraf, Matthew
- Schwarz, Jacob B
- Hackos, David H
- Weimer, Robby M
- Sheng, Morgan
- Gill, T Michael
- Scearce-Levie, Kimberly
- Palop, Jorge J
Producer: 20210212
In:
Cell reports vol. 30
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27.
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Discovery of a Potent (4 R,5 S)-4-Fluoro-5-methylproline Sulfonamide Transient Receptor Potential Ankyrin 1 Antagonist and Its Methylene Phosphate Prodrug Guided by Molecular Modeling. [electronic resource] by
- Chen, Huifen
- Volgraf, Matthew
- Do, Steven
- Kolesnikov, Aleksandr
- Shore, Daniel G
- Verma, Vishal A
- Villemure, Elisia
- Wang, Lan
- Chen, Yong
- Hu, Baihua
- Lu, Ai-Jun
- Wu, Guosheng
- Xu, Xiaofeng
- Yuen, Po-Wai
- Zhang, Yamin
- Erickson, Shawn D
- Dahl, Martin
- Brotherton-Pleiss, Christine
- Tay, Suzanne
- Ly, Justin Q
- Murray, Lesley J
- Chen, Jun
- Amm, Desiree
- Lange, Wienke
- Hackos, David H
- Reese, Rebecca M
- Shields, Shannon D
- Lyssikatos, Joseph P
- Safina, Brian S
- Estrada, Anthony A
Producer: 20190423
In:
Journal of medicinal chemistry vol. 61
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28.
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Structure- and Ligand-Based Discovery of Chromane Arylsulfonamide Na [electronic resource] by
- McKerrall, Steven J
- Nguyen, Teresa
- Lai, Kwong Wah
- Bergeron, Philippe
- Deng, Lunbin
- DiPasquale, Antonio
- Chang, Jae H
- Chen, Jun
- Chernov-Rogan, Tania
- Hackos, David H
- Maher, Jonathan
- Ortwine, Daniel F
- Pang, Jodie
- Payandeh, Jian
- Proctor, William R
- Shields, Shannon D
- Vogt, Jennifer
- Ji, Pengfei
- Liu, Wenfeng
- Ballini, Elisa
- Schumann, Lilia
- Tarozzo, Glauco
- Bankar, Girish
- Chowdhury, Sultan
- Hasan, Abid
- Johnson, J P
- Khakh, Kuldip
- Lin, Sophia
- Cohen, Charles J
- Dehnhardt, Christoph M
- Safina, Brian S
- Sutherlin, Daniel P
Producer: 20200608
In:
Journal of medicinal chemistry vol. 62
Availability: No items available.
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29.
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Discovery of GluN2A-Selective NMDA Receptor Positive Allosteric Modulators (PAMs): Tuning Deactivation Kinetics via Structure-Based Design. [electronic resource] by
- Volgraf, Matthew
- Sellers, Benjamin D
- Jiang, Yu
- Wu, Guosheng
- Ly, Cuong Q
- Villemure, Elisia
- Pastor, Richard M
- Yuen, Po-wai
- Lu, Aijun
- Luo, Xifeng
- Liu, Mingcui
- Zhang, Shun
- Sun, Liang
- Fu, Yuhong
- Lupardus, Patrick J
- Wallweber, Heidi J A
- Liederer, Bianca M
- Deshmukh, Gauri
- Plise, Emile
- Tay, Suzanne
- Reynen, Paul
- Herrington, James
- Gustafson, Amy
- Liu, Yichin
- Dirksen, Akim
- Dietz, Matthias G A
- Liu, Yanzhou
- Wang, Tzu-Ming
- Hanson, Jesse E
- Hackos, David
- Scearce-Levie, Kimberly
- Schwarz, Jacob B
Producer: 20160823
In:
Journal of medicinal chemistry vol. 59
Availability: No items available.
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30.
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Structural basis of Nav1.7 inhibition by an isoform-selective small-molecule antagonist. [electronic resource] by
- Ahuja, Shivani
- Mukund, Susmith
- Deng, Lunbin
- Khakh, Kuldip
- Chang, Elaine
- Ho, Hoangdung
- Shriver, Stephanie
- Young, Clint
- Lin, Sophia
- Johnson, J P
- Wu, Ping
- Li, Jun
- Coons, Mary
- Tam, Christine
- Brillantes, Bobby
- Sampang, Honorio
- Mortara, Kyle
- Bowman, Krista K
- Clark, Kevin R
- Estevez, Alberto
- Xie, Zhiwei
- Verschoof, Henry
- Grimwood, Michael
- Dehnhardt, Christoph
- Andrez, Jean-Christophe
- Focken, Thilo
- Sutherlin, Daniel P
- Safina, Brian S
- Starovasnik, Melissa A
- Ortwine, Daniel F
- Franke, Yvonne
- Cohen, Charles J
- Hackos, David H
- Koth, Christopher M
- Payandeh, Jian
Producer: 20160113
In:
Science (New York, N.Y.) vol. 350
Availability: No items available.
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31.
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Identification of Selective Acyl Sulfonamide-Cycloalkylether Inhibitors of the Voltage-Gated Sodium Channel (Na [electronic resource] by
- Sun, Shaoyi
- Jia, Qi
- Zenova, Alla Y
- Wilson, Michael S
- Chowdhury, Sultan
- Focken, Thilo
- Li, Jun
- Decker, Shannon
- Grimwood, Michael E
- Andrez, Jean-Christophe
- Hemeon, Ivan
- Sheng, Tao
- Chen, Chien-An
- White, Andy
- Hackos, David H
- Deng, Lunbin
- Bankar, Girish
- Khakh, Kuldip
- Chang, Elaine
- Kwan, Rainbow
- Lin, Sophia
- Nelkenbrecher, Karen
- Sellers, Benjamin D
- DiPasquale, Antonio G
- Chang, Jae
- Pang, Jodie
- Sojo, Luis
- Lindgren, Andrea
- Waldbrook, Matthew
- Xie, Zhiwei
- Young, Clint
- Johnson, James P
- Robinette, C Lee
- Cohen, Charles J
- Safina, Brian S
- Sutherlin, Daniel P
- Ortwine, Daniel F
- Dehnhardt, Christoph M
Producer: 20191017
In:
Journal of medicinal chemistry vol. 62
Availability: No items available.
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32.
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Design of Conformationally Constrained Acyl Sulfonamide Isosteres: Identification of N-([1,2,4]Triazolo[4,3- a]pyridin-3-yl)methane-sulfonamides as Potent and Selective hNa [electronic resource] by
- Focken, Thilo
- Chowdhury, Sultan
- Zenova, Alla
- Grimwood, Michael E
- Chabot, Christine
- Sheng, Tao
- Hemeon, Ivan
- Decker, Shannon M
- Wilson, Michael
- Bichler, Paul
- Jia, Qi
- Sun, Shaoyi
- Young, Clint
- Lin, Sophia
- Goodchild, Samuel J
- Shuart, Noah G
- Chang, Elaine
- Xie, Zhiwei
- Li, Bowen
- Khakh, Kuldip
- Bankar, Girish
- Waldbrook, Matthew
- Kwan, Rainbow
- Nelkenbrecher, Karen
- Karimi Tari, Parisa
- Chahal, Navjot
- Sojo, Luis
- Robinette, C Lee
- White, Andrew D
- Chen, Chien-An
- Zhang, Yi
- Pang, Jodie
- Chang, Jae H
- Hackos, David H
- Johnson, J P
- Cohen, Charles J
- Ortwine, Daniel F
- Sutherlin, Daniel P
- Dehnhardt, Christoph M
- Safina, Brian S
Producer: 20190520
In:
Journal of medicinal chemistry vol. 61
Availability: No items available.
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