Results
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21.
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Use of structure-based drug design approaches to obtain novel anthranilic acid acyl carrier protein synthase inhibitors. [electronic resource] by
- Joseph-McCarthy, Diane
- Parris, Kevin
- Huang, Adrian
- Failli, Amedeo
- Quagliato, Dominick
- Dushin, Elizabeth Glasfeld
- Novikova, Elena
- Severina, Elena
- Tuckman, Margareta
- Petersen, Peter J
- Dean, Charles
- Fritz, Christian C
- Meshulam, Tova
- DeCenzo, Maureen
- Dick, Larry
- McFadyen, Iain J
- Somers, William S
- Lovering, Frank
- Gilbert, Adam M
Producer: 20060207
In:
Journal of medicinal chemistry vol. 48
Availability: No items available.
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22.
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Chiral Sulfoxide-Induced Single Turn Peptide α-Helicity. [electronic resource] by
- Zhang, Qingzhou
- Jiang, Fan
- Zhao, Bingchuan
- Lin, Huacan
- Tian, Yuan
- Xie, Mingsheng
- Bai, Guoyun
- Gilbert, Adam M
- Goetz, Gilles H
- Liras, Spiros
- Mathiowetz, Alan A
- Price, David A
- Song, Kun
- Tu, Meihua
- Wu, Yujie
- Wang, Tao
- Flanagan, Mark E
- Wu, Yun-Dong
- Li, Zigang
Producer: 20180606
In:
Scientific reports vol. 6
Availability: No items available.
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23.
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Structure-Based Approach To Identify 5-[4-Hydroxyphenyl]pyrrole-2-carbonitrile Derivatives as Potent and Tissue Selective Androgen Receptor Modulators. [electronic resource] by
- Unwalla, Ray
- Mousseau, James J
- Fadeyi, Olugbeminiyi O
- Choi, Chulho
- Parris, Kevin
- Hu, Baihua
- Kenney, Thomas
- Chippari, Susan
- McNally, Christopher
- Vishwanathan, Karthick
- Kilbourne, Edward
- Thompson, Catherine
- Nagpal, Sunil
- Wrobel, Jay
- Yudt, Matthew
- Morris, Carl A
- Powell, Dennis
- Gilbert, Adam M
- Chekler, Eugene L Piatnitski
Producer: 20170905
In:
Journal of medicinal chemistry vol. 60
Availability: No items available.
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24.
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Novel imidazolopyrimidines as dual PI3-Kinase/mTOR inhibitors. [electronic resource] by
- Venkatesan, Aranapakam M
- Dehnhardt, Christoph M
- Chen, Zecheng
- Santos, Efren Delos
- Dos Santos, Osvaldo
- Bursavich, Matthew
- Gilbert, Adam M
- Ellingboe, John W
- Ayral-Kaloustian, Semiramis
- Khafizova, Gulnaz
- Brooijmans, Natasja
- Mallon, Robert
- Hollander, Irwin
- Feldberg, Larry
- Lucas, Judy
- Yu, Ker
- Gibbons, Jay
- Abraham, Robert
- Mansour, Tarek S
Producer: 20100420
In:
Bioorganic & medicinal chemistry letters vol. 20
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25.
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1-(2-Hydroxy-2-methyl-3-phenoxypropanoyl)indoline-4-carbonitrile derivatives as potent and tissue selective androgen receptor modulators. [electronic resource] by
- Piatnitski Chekler, Eugene L
- Unwalla, Rayomond
- Khan, Taukeer A
- Tangirala, Raghuram S
- Johnson, Mark
- St Andre, Michael
- Anderson, James T
- Kenney, Thomas
- Chiparri, Sue
- McNally, Chris
- Kilbourne, Edward
- Thompson, Catherine
- Nagpal, Sunil
- Weber, Gregory
- Schelling, Scott
- Owens, Jane
- Morris, Carl A
- Powell, Dennis
- Verhoest, Patrick R
- Gilbert, Adam M
Producer: 20140527
In:
Journal of medicinal chemistry vol. 57
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26.
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A road map to evaluate the proteome-wide selectivity of covalent kinase inhibitors. [electronic resource] by
- Lanning, Bryan R
- Whitby, Landon R
- Dix, Melissa M
- Douhan, John
- Gilbert, Adam M
- Hett, Erik C
- Johnson, Theodore O
- Joslyn, Chris
- Kath, John C
- Niessen, Sherry
- Roberts, Lee R
- Schnute, Mark E
- Wang, Chu
- Hulce, Jonathan J
- Wei, Baoxian
- Whiteley, Laurence O
- Hayward, Matthew M
- Cravatt, Benjamin F
Producer: 20141021
In:
Nature chemical biology vol. 10
Availability: No items available.
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27.
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Hit to lead studies on (hetero)arylpyrimidines--agonists of the canonical Wnt-beta-catenin cellular messaging system. [electronic resource] by
- Gilbert, Adam M
- Bursavich, Matthew G
- Alon, Nippa
- Bhat, Bheem M
- Bex, Frederick J
- Cain, Michael
- Coleburn, Valerie
- Gironda, Virginia
- Green, Paula
- Hauze, Diane B
- Kharode, Yogendra
- Krishnamurthy, Girija
- Kirisits, Matthew
- Lam, Ho-Sun
- Liu, Yao-Bin
- Lombardi, Sabrina
- Matteo, Jeanne
- Murrills, Richard
- Robinson, John A
- Selim, Sally
- Sharp, Michael
- Unwalla, Raymond
- Varadarajan, Usha
- Zhao, Weiguang
- Yaworsky, Paul J
Producer: 20100506
In:
Bioorganic & medicinal chemistry letters vol. 20
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28.
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Design of a Janus Kinase 3 (JAK3) Specific Inhibitor 1-((2S,5R)-5-((7H-Pyrrolo[2,3-d]pyrimidin-4-yl)amino)-2-methylpiperidin-1-yl)prop-2-en-1-one (PF-06651600) Allowing for the Interrogation of JAK3 Signaling in Humans. [electronic resource] by
- Thorarensen, Atli
- Dowty, Martin E
- Banker, Mary Ellen
- Juba, Brian
- Jussif, Jason
- Lin, Tsung
- Vincent, Fabien
- Czerwinski, Robert M
- Casimiro-Garcia, Agustin
- Unwalla, Ray
- Trujillo, John I
- Liang, Sidney
- Balbo, Paul
- Che, Ye
- Gilbert, Adam M
- Brown, Matthew F
- Hayward, Matthew
- Montgomery, Justin
- Leung, Louis
- Yang, Xin
- Soucy, Sarah
- Hegen, Martin
- Coe, Jotham
- Langille, Jonathan
- Vajdos, Felix
- Chrencik, Jill
- Telliez, Jean-Baptiste
Producer: 20170807
In:
Journal of medicinal chemistry vol. 60
Availability: No items available.
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29.
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Chemical and computational methods for the characterization of covalent reactive groups for the prospective design of irreversible inhibitors. [electronic resource] by
- Flanagan, Mark E
- Abramite, Joseph A
- Anderson, Dennis P
- Aulabaugh, Ann
- Dahal, Upendra P
- Gilbert, Adam M
- Li, Chao
- Montgomery, Justin
- Oppenheimer, Stacey R
- Ryder, Tim
- Schuff, Brandon P
- Uccello, Daniel P
- Walker, Gregory S
- Wu, Yan
- Brown, Matthew F
- Chen, Jinshan M
- Hayward, Matthew M
- Noe, Mark C
- Obach, R Scott
- Philippe, Laurence
- Shanmugasundaram, Veerabahu
- Shapiro, Michael J
- Starr, Jeremy
- Stroh, Justin
- Che, Ye
Producer: 20150226
In:
Journal of medicinal chemistry vol. 57
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30.
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Discovery of Trifluoromethyl Glycol Carbamates as Potent and Selective Covalent Monoacylglycerol Lipase (MAGL) Inhibitors for Treatment of Neuroinflammation. [electronic resource] by
- McAllister, Laura A
- Butler, Christopher R
- Mente, Scot
- O'Neil, Steven V
- Fonseca, Kari R
- Piro, Justin R
- Cianfrogna, Julie A
- Foley, Timothy L
- Gilbert, Adam M
- Harris, Anthony R
- Helal, Christopher J
- Johnson, Douglas S
- Montgomery, Justin I
- Nason, Deane M
- Noell, Stephen
- Pandit, Jayvardhan
- Rogers, Bruce N
- Samad, Tarek A
- Shaffer, Christopher L
- da Silva, Rafael G
- Uccello, Daniel P
- Webb, Damien
- Brodney, Michael A
Producer: 20190417
In:
Journal of medicinal chemistry vol. 61
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Discovery of a Selective Covalent Inhibitor of Lysophospholipase-like 1 (LYPLAL1) as a Tool to Evaluate the Role of this Serine Hydrolase in Metabolism. [electronic resource] by
- Ahn, Kay
- Boehm, Markus
- Brown, Matthew F
- Calloway, Jessica
- Che, Ye
- Chen, Jinshan
- Fennell, Kimberly F
- Geoghegan, Kieran F
- Gilbert, Adam M
- Gutierrez, Jemy A
- Kalgutkar, Amit S
- Lanba, Adhiraj
- Limberakis, Chris
- Magee, Thomas V
- O'Doherty, Inish
- Oliver, Robert
- Pabst, Brandon
- Pandit, Jayvardhan
- Parris, Kevin
- Pfefferkorn, Jeffrey A
- Rolph, Timothy P
- Patel, Rushi
- Schuff, Brandon
- Shanmugasundaram, Veerabahu
- Starr, Jeremy T
- Varghese, Alison H
- Vera, Nicholas B
- Vernochet, Cecile
- Yan, Jiangli
Producer: 20170626
In:
ACS chemical biology vol. 11
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32.
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(1-(4-(Naphthalen-2-yl)pyrimidin-2-yl)piperidin-4-yl)methanamine: a wingless beta-catenin agonist that increases bone formation rate. [electronic resource] by
- Pelletier, Jeffrey C
- Lundquist, Joseph T
- Gilbert, Adam M
- Alon, Nipa
- Bex, Frederick J
- Bhat, Bheem M
- Bursavich, Mattew G
- Coleburn, Valerie E
- Felix, Luciana A
- Green, Daniel M
- Green, Paula
- Hauze, Diane B
- Kharode, Yogendra P
- Lam, Ho-Sun
- Lockhead, Susan R
- Magolda, Ronald L
- Matteo, Jeanne J
- Mehlmann, John F
- Milligan, Colleen
- Murrills, Richard J
- Pirrello, Jennifer
- Selim, Sally
- Sharp, Michael C
- Unwalla, Ray J
- Vera, Matthew D
- Wrobel, Jay E
- Yaworsky, Paul
- Bodine, Peter V N
Producer: 20091221
In:
Journal of medicinal chemistry vol. 52
Availability: No items available.
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33.
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Discovery of a JAK3-Selective Inhibitor: Functional Differentiation of JAK3-Selective Inhibition over pan-JAK or JAK1-Selective Inhibition. [electronic resource] by
- Telliez, Jean-Baptiste
- Dowty, Martin E
- Wang, Lu
- Jussif, Jason
- Lin, Tsung
- Li, Li
- Moy, Erick
- Balbo, Paul
- Li, Wei
- Zhao, Yajuan
- Crouse, Kimberly
- Dickinson, Caitlyn
- Symanowicz, Peter
- Hegen, Martin
- Banker, Mary Ellen
- Vincent, Fabien
- Unwalla, Ray
- Liang, Sidney
- Gilbert, Adam M
- Brown, Matthew F
- Hayward, Matthew
- Montgomery, Justin
- Yang, Xin
- Bauman, Jonathan
- Trujillo, John I
- Casimiro-Garcia, Agustin
- Vajdos, Felix F
- Leung, Louis
- Geoghegan, Kieran F
- Quazi, Amira
- Xuan, Dejun
- Jones, Lyn
- Hett, Erik
- Wright, Katherine
- Clark, James D
- Thorarensen, Atli
Producer: 20170310
In:
ACS chemical biology vol. 11
Availability: No items available.
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34.
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Delineating the role of cooperativity in the design of potent PROTACs for BTK. [electronic resource] by
- Zorba, Adelajda
- Nguyen, Chuong
- Xu, Yingrong
- Starr, Jeremy
- Borzilleri, Kris
- Smith, James
- Zhu, Hongyao
- Farley, Kathleen A
- Ding, WeiDong
- Schiemer, James
- Feng, Xidong
- Chang, Jeanne S
- Uccello, Daniel P
- Young, Jennifer A
- Garcia-Irrizary, Carmen N
- Czabaniuk, Lara
- Schuff, Brandon
- Oliver, Robert
- Montgomery, Justin
- Hayward, Matthew M
- Coe, Jotham
- Chen, Jinshan
- Niosi, Mark
- Luthra, Suman
- Shah, Jaymin C
- El-Kattan, Ayman
- Qiu, Xiayang
- West, Graham M
- Noe, Mark C
- Shanmugasundaram, Veerabahu
- Gilbert, Adam M
- Brown, Matthew F
- Calabrese, Matthew F
Producer: 20180924
In:
Proceedings of the National Academy of Sciences of the United States of America vol. 115
Availability: No items available.
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