Results
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21.
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Structure-guided design of a selective BCL-X(L) inhibitor. [electronic resource] by
- Lessene, Guillaume
- Czabotar, Peter E
- Sleebs, Brad E
- Zobel, Kerry
- Lowes, Kym N
- Adams, Jerry M
- Baell, Jonathan B
- Colman, Peter M
- Deshayes, Kurt
- Fairbrother, Wayne J
- Flygare, John A
- Gibbons, Paul
- Kersten, Wilhelmus J A
- Kulasegaram, Sanji
- Moss, Rebecca M
- Parisot, John P
- Smith, Brian J
- Street, Ian P
- Yang, Hong
- Huang, David C S
- Watson, Keith G
Producer: 20130715
In:
Nature chemical biology vol. 9
Availability: No items available.
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22.
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Targeted drug delivery through the traceless release of tertiary and heteroaryl amines from antibody-drug conjugates. [electronic resource] by
- Staben, Leanna R
- Koenig, Stefan G
- Lehar, Sophie M
- Vandlen, Richard
- Zhang, Donglu
- Chuh, Josefa
- Yu, Shang-Fan
- Ng, Carl
- Guo, Jun
- Liu, Yanzhou
- Fourie-O'Donohue, Aimee
- Go, MaryAnn
- Linghu, Xin
- Segraves, Nathaniel L
- Wang, Tao
- Chen, Jinhua
- Wei, BinQing
- Phillips, Gail D Lewis
- Xu, Keyang
- Kozak, Katherine R
- Mariathasan, Sanjeev
- Flygare, John A
- Pillow, Thomas H
Producer: 20180820
In:
Nature chemistry vol. 8
Availability: No items available.
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23.
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Site-specific trastuzumab maytansinoid antibody-drug conjugates with improved therapeutic activity through linker and antibody engineering. [electronic resource] by
- Pillow, Thomas H
- Tien, Janet
- Parsons-Reponte, Kathryn L
- Bhakta, Sunil
- Li, Hao
- Staben, Leanna R
- Li, Guangmin
- Chuh, Josefa
- Fourie-O'Donohue, Aimee
- Darwish, Martine
- Yip, Victor
- Liu, Luna
- Leipold, Douglas D
- Su, Dian
- Wu, Elmer
- Spencer, Susan D
- Shen, Ben-Quan
- Xu, Keyang
- Kozak, Katherine R
- Raab, Helga
- Vandlen, Richard
- Lewis Phillips, Gail D
- Scheller, Richard H
- Polakis, Paul
- Sliwkowski, Mark X
- Flygare, John A
- Junutula, Jagath R
Producer: 20141218
In:
Journal of medicinal chemistry vol. 57
Availability: No items available.
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24.
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Structure-Guided Rescaffolding of Selective Antagonists of BCL-XL. [electronic resource] by
- Koehler, Michael F T
- Bergeron, Philippe
- Choo, Edna F
- Lau, Kevin
- Ndubaku, Chudi
- Dudley, Danette
- Gibbons, Paul
- Sleebs, Brad E
- Rye, Carl S
- Nikolakopoulos, George
- Bui, Chinh
- Kulasegaram, Sanji
- Kersten, Wilhelmus J A
- Smith, Brian J
- Czabotar, Peter E
- Colman, Peter M
- Huang, David C S
- Baell, Jonathan B
- Watson, Keith G
- Hasvold, Lisa
- Tao, Zhi-Fu
- Wang, Le
- Souers, Andrew J
- Elmore, Steven W
- Flygare, John A
- Fairbrother, Wayne J
- Lessene, Guillaume
Producer: 20140619
In:
ACS medicinal chemistry letters vol. 5
Availability: No items available.
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25.
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Novel antibody-antibiotic conjugate eliminates intracellular S. aureus. [electronic resource] by
- Lehar, Sophie M
- Pillow, Thomas
- Xu, Min
- Staben, Leanna
- Kajihara, Kimberly K
- Vandlen, Richard
- DePalatis, Laura
- Raab, Helga
- Hazenbos, Wouter L
- Morisaki, J Hiroshi
- Kim, Janice
- Park, Summer
- Darwish, Martine
- Lee, Byoung-Chul
- Hernandez, Hilda
- Loyet, Kelly M
- Lupardus, Patrick
- Fong, Rina
- Yan, Donghong
- Chalouni, Cecile
- Luis, Elizabeth
- Khalfin, Yana
- Plise, Emile
- Cheong, Jonathan
- Lyssikatos, Joseph P
- Strandh, Magnus
- Koefoed, Klaus
- Andersen, Peter S
- Flygare, John A
- Wah Tan, Man
- Brown, Eric J
- Mariathasan, Sanjeev
Producer: 20151224
In:
Nature vol. 527
Availability: No items available.
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26.
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Discovery of Peptidomimetic Antibody-Drug Conjugate Linkers with Enhanced Protease Specificity. [electronic resource] by
- Wei, BinQing
- Gunzner-Toste, Janet
- Yao, Hui
- Wang, Tao
- Wang, Jing
- Xu, Zijin
- Chen, Jinhua
- Wai, John
- Nonomiya, Jim
- Tsai, Siao Ping
- Chuh, Josefa
- Kozak, Katherine R
- Liu, Yichin
- Yu, Shang-Fan
- Lau, Jeff
- Li, Guangmin
- Phillips, Gail D
- Leipold, Doug
- Kamath, Amrita
- Su, Dian
- Xu, Keyang
- Eigenbrot, Charles
- Steinbacher, Stefan
- Ohri, Rachana
- Raab, Helga
- Staben, Leanna R
- Zhao, Guiling
- Flygare, John A
- Pillow, Thomas H
- Verma, Vishal
- Masterson, Luke A
- Howard, Philip W
- Safina, Brian
Producer: 20190218
In:
Journal of medicinal chemistry vol. 61
Availability: No items available.
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27.
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Modulating Therapeutic Activity and Toxicity of Pyrrolobenzodiazepine Antibody-Drug Conjugates with Self-Immolative Disulfide Linkers. [electronic resource] by
- Pillow, Thomas H
- Schutten, Melissa
- Yu, Shang-Fan
- Ohri, Rachana
- Sadowsky, Jack
- Poon, Kirsten Achilles
- Solis, Willy
- Zhong, Fiona
- Del Rosario, Geoffrey
- Go, Mary Ann T
- Lau, Jeffrey
- Yee, Sharon
- He, Jintang
- Liu, Luna
- Ng, Carl
- Xu, Keyang
- Leipold, Douglas D
- Kamath, Amrita V
- Zhang, Donglu
- Masterson, Luke
- Gregson, Stephen J
- Howard, Philip W
- Fang, Fan
- Chen, Jinhua
- Gunzner-Toste, Janet
- Kozak, Katherine K
- Spencer, Susan
- Polakis, Paul
- Polson, Andrew G
- Flygare, John A
- Junutula, Jagath R
Producer: 20180221
In:
Molecular cancer therapeutics vol. 16
Availability: No items available.
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28.
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Discovery of a potent small-molecule antagonist of inhibitor of apoptosis (IAP) proteins and clinical candidate for the treatment of cancer (GDC-0152). [electronic resource] by
- Flygare, John A
- Beresini, Maureen
- Budha, Nageshwar
- Chan, Helen
- Chan, Iris T
- Cheeti, Sravanthi
- Cohen, Frederick
- Deshayes, Kurt
- Doerner, Karl
- Eckhardt, S Gail
- Elliott, Linda O
- Feng, Bainian
- Franklin, Matthew C
- Reisner, Stacy Frankovitz
- Gazzard, Lewis
- Halladay, Jason
- Hymowitz, Sarah G
- La, Hank
- LoRusso, Patricia
- Maurer, Brigitte
- Murray, Lesley
- Plise, Emile
- Quan, Clifford
- Stephan, Jean-Philippe
- Young, Shin G
- Tom, Jeffrey
- Tsui, Vickie
- Um, Joanne
- Varfolomeev, Eugene
- Vucic, Domagoj
- Wagner, Andrew J
- Wallweber, Heidi J A
- Wang, Lan
- Ware, Joseph
- Wen, Zhaoyang
- Wong, Harvey
- Wong, Jonathan M
- Wong, Melisa
- Wong, Susan
- Yu, Ron
- Zobel, Kerry
- Fairbrother, Wayne J
Producer: 20120912
In:
Journal of medicinal chemistry vol. 55
Availability: No items available.
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29.
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Discovery of a Potent and Selective BCL-XL Inhibitor with in Vivo Activity. [electronic resource] by
- Tao, Zhi-Fu
- Hasvold, Lisa
- Wang, Le
- Wang, Xilu
- Petros, Andrew M
- Park, Chang H
- Boghaert, Erwin R
- Catron, Nathaniel D
- Chen, Jun
- Colman, Peter M
- Czabotar, Peter E
- Deshayes, Kurt
- Fairbrother, Wayne J
- Flygare, John A
- Hymowitz, Sarah G
- Jin, Sha
- Judge, Russell A
- Koehler, Michael F T
- Kovar, Peter J
- Lessene, Guillaume
- Mitten, Michael J
- Ndubaku, Chudi O
- Nimmer, Paul
- Purkey, Hans E
- Oleksijew, Anatol
- Phillips, Darren C
- Sleebs, Brad E
- Smith, Brian J
- Smith, Morey L
- Tahir, Stephen K
- Watson, Keith G
- Xiao, Yu
- Xue, John
- Zhang, Haichao
- Zobel, Kerry
- Rosenberg, Saul H
- Tse, Chris
- Leverson, Joel D
- Elmore, Steven W
- Souers, Andrew J
Producer: 20141014
In:
ACS medicinal chemistry letters vol. 5
Availability: No items available.
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