Results
|
21.
|
Discovery of a potent, selective, and orally bioavailable c-Met inhibitor: 1-(2-hydroxy-2-methylpropyl)-N-(5-(7-methoxyquinolin-4-yloxy)pyridin-2-yl)-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide (AMG 458). [electronic resource] by
- Liu, Longbin
- Siegmund, Aaron
- Xi, Ning
- Kaplan-Lefko, Paula
- Rex, Karen
- Chen, April
- Lin, Jasmine
- Moriguchi, Jodi
- Berry, Loren
- Huang, Liyue
- Teffera, Yohannes
- Yang, Yajing
- Zhang, Yihong
- Bellon, Steven F
- Lee, Matthew
- Shimanovich, Roman
- Bak, Annette
- Dominguez, Celia
- Norman, Mark H
- Harmange, Jean-Christophe
- Dussault, Isabelle
- Kim, Tae-Seong
Producer: 20080812
In:
Journal of medicinal chemistry vol. 51
Availability: No items available.
|
|
22.
|
In Vitro and In Vivo Activity of AMG 337, a Potent and Selective MET Kinase Inhibitor, in MET-Dependent Cancer Models. [electronic resource] by
- Hughes, Paul E
- Rex, Karen
- Caenepeel, Sean
- Yang, Yajing
- Zhang, Yihong
- Broome, Martin A
- Kha, Hue T
- Burgess, Teresa L
- Amore, Benny
- Kaplan-Lefko, Paula J
- Moriguchi, Jodi
- Werner, Jonathan
- Damore, Michael A
- Baker, Daniel
- Choquette, Deborah M
- Harmange, Jean-Christophe
- Radinsky, Robert
- Kendall, Richard
- Dussault, Isabelle
- Coxon, Angela
Producer: 20170629
In:
Molecular cancer therapeutics vol. 15
Availability: No items available.
|
|
23.
|
Discovery of potent and selective 8-fluorotriazolopyridine c-Met inhibitors. [electronic resource] by
- Peterson, Emily A
- Teffera, Yohannes
- Albrecht, Brian K
- Bauer, David
- Bellon, Steven F
- Boezio, Alessandro
- Boezio, Christiane
- Broome, Martin A
- Choquette, Deborah
- Copeland, Katrina W
- Dussault, Isabelle
- Lewis, Richard
- Lin, Min-Hwa Jasmine
- Lohman, Julia
- Liu, Jingzhou
- Potashman, Michele
- Rex, Karen
- Shimanovich, Roman
- Whittington, Douglas A
- Vaida, Karina R
- Harmange, Jean-Christophe
Producer: 20150615
In:
Journal of medicinal chemistry vol. 58
Availability: No items available.
|
|
24.
|
Preclinical evaluation of AMG 900, a novel potent and highly selective pan-aurora kinase inhibitor with activity in taxane-resistant tumor cell lines. [electronic resource] by
- Payton, Marc
- Bush, Tammy L
- Chung, Grace
- Ziegler, Beth
- Eden, Patrick
- McElroy, Patricia
- Ross, Sandra
- Cee, Victor J
- Deak, Holly L
- Hodous, Brian L
- Nguyen, Hanh Nho
- Olivieri, Philip R
- Romero, Karina
- Schenkel, Laurie B
- Bak, Annette
- Stanton, Mary
- Dussault, Isabelle
- Patel, Vinod F
- Geuns-Meyer, Stephanie
- Radinsky, Robert
- Kendall, Richard L
Producer: 20110210
In:
Cancer research vol. 70
Availability: No items available.
|
|
25.
|
Correction to Discovery of Potent and Selective 8-Fluorotriazolopyridine c-Met Inhibitors. [electronic resource] by
- Peterson, Emily A
- Teffera, Yohannes
- Albrecht, Brian K
- Bauer, David
- Bellon, Steven F
- Boezio, Alessandro
- Boezio, Christiane
- Broome, Martin A
- Choquette, Deborah
- Copeland, Katrina W
- Dussault, Isabelle
- Lewis, Richard
- Lin, Min-Hwa Jasmine
- Lohman, Julia
- Liu, Jingzhou
- Potashman, Michele
- Rex, Karen
- Shimanovich, Roman
- Whittington, Douglas A
- Vaida, Karina R
- Harmange, Jean-Christophe
Producer: 20150716
In:
Journal of medicinal chemistry vol. 58
Availability: No items available.
|
|
26.
|
STK33 kinase activity is nonessential in KRAS-dependent cancer cells. [electronic resource] by
- Babij, Carol
- Zhang, Yihong
- Kurzeja, Robert J
- Munzli, Anke
- Shehabeldin, Amro
- Fernando, Manory
- Quon, Kim
- Kassner, Paul D
- Ruefli-Brasse, Astrid A
- Watson, Vivienne J
- Fajardo, Flordeliza
- Jackson, Angela
- Zondlo, James
- Sun, Yu
- Ellison, Aaron R
- Plewa, Cherylene A
- San, Miguel Tisha
- Robinson, John
- McCarter, John
- Schwandner, Ralf
- Judd, Ted
- Carnahan, Josette
- Dussault, Isabelle
Producer: 20111025
In:
Cancer research vol. 71
Availability: No items available.
|
|
27.
|
Discovery of (R)-6-(1-(8-Fluoro-6-(1-methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl)ethyl)-3-(2-methoxyethoxy)-1,6-naphthyridin-5(6H)-one (AMG 337), a Potent and Selective Inhibitor of MET with High Unbound Target Coverage and Robust In Vivo Antitumor Activity. [electronic resource] by
- Boezio, Alessandro A
- Copeland, Katrina W
- Rex, Karen
- K Albrecht, Brian
- Bauer, David
- Bellon, Steven F
- Boezio, Christiane
- Broome, Martin A
- Choquette, Deborah
- Coxon, Angela
- Dussault, Isabelle
- Hirai, Satoko
- Lewis, Richard
- Lin, Min-Hwa Jasmine
- Lohman, Julia
- Liu, Jingzhou
- Peterson, Emily A
- Potashman, Michele
- Shimanovich, Roman
- Teffera, Yohannes
- Whittington, Douglas A
- Vaida, Karina R
- Harmange, Jean-Christophe
Producer: 20160823
In:
Journal of medicinal chemistry vol. 59
Availability: No items available.
|
|
28.
|
Design, synthesis, and biological evaluation of potent c-Met inhibitors. [electronic resource] by
- D'Angelo, Noel D
- Bellon, Steven F
- Booker, Shon K
- Cheng, Yuan
- Coxon, Angela
- Dominguez, Celia
- Fellows, Ingrid
- Hoffman, Douglas
- Hungate, Randall
- Kaplan-Lefko, Paula
- Lee, Matthew R
- Li, Chun
- Liu, Longbin
- Rainbeau, Elizabeth
- Reider, Paul J
- Rex, Karen
- Siegmund, Aaron
- Sun, Yaxiong
- Tasker, Andrew S
- Xi, Ning
- Xu, Shimin
- Yang, Yajing
- Zhang, Yihong
- Burgess, Teresa L
- Dussault, Isabelle
- Kim, Tae-Seong
Producer: 20081009
In:
Journal of medicinal chemistry vol. 51
Availability: No items available.
|
|
29.
|
Discovery and optimization of potent and selective triazolopyridazine series of c-Met inhibitors. [electronic resource] by
- Boezio, Alessandro A
- Berry, Loren
- Albrecht, Brian K
- Bauer, David
- Bellon, Steven F
- Bode, Christiane
- Chen, April
- Choquette, Deborah
- Dussault, Isabelle
- Fang, Mei
- Hirai, Satoko
- Kaplan-Lefko, Paula
- Larrow, Jay F
- Lin, Min-Hwa Jasmine
- Lohman, Julia
- Potashman, Michele H
- Qu, Yusheng
- Rex, Karen
- Santostefano, Michael
- Shah, Kavita
- Shimanovich, Roman
- Springer, Stephanie K
- Teffera, Yohannes
- Yang, Yajing
- Zhang, Yihong
- Harmange, Jean-Christophe
Producer: 20100127
In:
Bioorganic & medicinal chemistry letters vol. 19
Availability: No items available.
|
|
30.
|
Discovery and optimization of triazolopyridazines as potent and selective inhibitors of the c-Met kinase. [electronic resource] by
- Albrecht, Brian K
- Harmange, Jean-Christophe
- Bauer, David
- Berry, Loren
- Bode, Christiane
- Boezio, Alessandro A
- Chen, April
- Choquette, Deborah
- Dussault, Isabelle
- Fridrich, Cary
- Hirai, Satoko
- Hoffman, Doug
- Larrow, Jay F
- Kaplan-Lefko, Paula
- Lin, Jasmine
- Lohman, Julia
- Long, Alexander M
- Moriguchi, Jodi
- O'Connor, Anne
- Potashman, Michele H
- Reese, Monica
- Rex, Karen
- Siegmund, Aaron
- Shah, Kavita
- Shimanovich, Roman
- Springer, Stephanie K
- Teffera, Yohannes
- Yang, Yajing
- Zhang, Yihong
- Bellon, Steven F
Producer: 20080709
In:
Journal of medicinal chemistry vol. 51
Availability: No items available.
|