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21.
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Immunization reverses memory deficits without reducing brain Abeta burden in Alzheimer's disease model. [electronic resource] by
- Dodart, Jean-Cosme
- Bales, Kelly R
- Gannon, Kimberley S
- Greene, Stephen J
- DeMattos, Ronald B
- Mathis, Chantal
- DeLong, Cynthia A
- Wu, Su
- Wu, Xin
- Holtzman, David M
- Paul, Steven M
Producer: 20020513
In:
Nature neuroscience vol. 5
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22.
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Low-density lipoprotein receptor overexpression enhances the rate of brain-to-blood Aβ clearance in a mouse model of β-amyloidosis. [electronic resource] by
- Castellano, Joseph M
- Deane, Rashid
- Gottesdiener, Andrew J
- Verghese, Philip B
- Stewart, Floy R
- West, Tim
- Paoletti, Andrew C
- Kasper, Tristan R
- DeMattos, Ronald B
- Zlokovic, Berislav V
- Holtzman, David M
Producer: 20121210
In:
Proceedings of the National Academy of Sciences of the United States of America vol. 109
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23.
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The low density lipoprotein receptor regulates the level of central nervous system human and murine apolipoprotein E but does not modify amyloid plaque pathology in PDAPP mice. [electronic resource] by
- Fryer, John D
- Demattos, Ronald B
- McCormick, Lynn M
- O'Dell, Mark A
- Spinner, Michael L
- Bales, Kelly R
- Paul, Steven M
- Sullivan, Patrick M
- Parsadanian, Maia
- Bu, Guojun
- Holtzman, David M
Producer: 20050816
In:
The Journal of biological chemistry vol. 280
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24.
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Challenges, solutions, and recommendations for Alzheimer's disease combination therapy. [electronic resource] by
- Hendrix, James A
- Bateman, Randall J
- Brashear, H Robert
- Duggan, Cynthia
- Carrillo, Maria C
- Bain, Lisa J
- DeMattos, Ronald
- Katz, Russell G
- Ostrowitzki, Susanne
- Siemers, Eric
- Sperling, Reisa
- Vitolo, Ottavio V
Producer: 20171023
In:
Alzheimer's & dementia : the journal of the Alzheimer's Association vol. 12
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25.
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ApoE and clusterin cooperatively suppress Abeta levels and deposition: evidence that ApoE regulates extracellular Abeta metabolism in vivo. [electronic resource] by
- DeMattos, Ronald B
- Cirrito, John R
- Parsadanian, Maia
- May, Patrick C
- O'Dell, Mark A
- Taylor, Jennie W
- Harmony, Judith A K
- Aronow, Bruce J
- Bales, Kelly R
- Paul, Steven M
- Holtzman, David M
Producer: 20050831
In:
Neuron vol. 41
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26.
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Production and characterization of astrocyte-derived human apolipoprotein E isoforms from immortalized astrocytes and their interactions with amyloid-beta. [electronic resource] by
- Morikawa, Masayuki
- Fryer, John D
- Sullivan, Patrick M
- Christopher, Erin A
- Wahrle, Suzanne E
- DeMattos, Ronald B
- O'Dell, Mark A
- Fagan, Anne M
- Lashuel, Hilal A
- Walz, Thomas
- Asai, Kiyofumi
- Holtzman, David M
Producer: 20050712
In:
Neurobiology of disease vol. 19
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27.
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A liver X receptor and retinoid X receptor heterodimer mediates apolipoprotein E expression, secretion and cholesterol homeostasis in astrocytes. [electronic resource] by
- Liang, Yu
- Lin, Suizhen
- Beyer, Thomas P
- Zhang, Youyan
- Wu, Xin
- Bales, Kelly R
- DeMattos, Ronald B
- May, Patrick C
- Li, Shuyu Dan
- Jiang, Xian-Cheng
- Eacho, Patrick I
- Cao, Guoqing
- Paul, Steven M
Producer: 20040224
In:
Journal of neurochemistry vol. 88
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28.
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Evidence for peripheral clearance of cerebral Abeta protein following chronic, active Abeta immunization in PSAPP mice. [electronic resource] by
- Lemere, Cynthia A
- Spooner, Edward T
- LaFrancois, John
- Malester, Brian
- Mori, Chica
- Leverone, Jodi F
- Matsuoka, Yasuji
- Taylor, Jennie W
- DeMattos, Ronald B
- Holtzman, David M
- Clements, John D
- Selkoe, Dennis J
- Duff, Karen E
Producer: 20031029
In:
Neurobiology of disease vol. 14
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29.
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In vivo assessment of brain interstitial fluid with microdialysis reveals plaque-associated changes in amyloid-beta metabolism and half-life. [electronic resource] by
- Cirrito, John R
- May, Patrick C
- O'Dell, Mark A
- Taylor, Jennie W
- Parsadanian, Maia
- Cramer, Jeffrey W
- Audia, James E
- Nissen, Jeffrey S
- Bales, Kelly R
- Paul, Steven M
- DeMattos, Ronald B
- Holtzman, David M
Producer: 20031112
In:
The Journal of neuroscience : the official journal of the Society for Neuroscience vol. 23
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30.
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A gamma-secretase inhibitor decreases amyloid-beta production in the central nervous system. [electronic resource] by
- Bateman, Randall J
- Siemers, Eric R
- Mawuenyega, Kwasi G
- Wen, Guolin
- Browning, Karen R
- Sigurdson, Wendy C
- Yarasheski, Kevin E
- Friedrich, Stuart W
- Demattos, Ronald B
- May, Patrick C
- Paul, Steven M
- Holtzman, David M
Producer: 20090904
In:
Annals of neurology vol. 66
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31.
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Validation of ELISA methods for quantification of total tau and phosporylated-tau181 in human cerebrospinal fluid with measurement in specimens from two Alzheimer's disease studies. [electronic resource] by
- Lachno, D Richard
- Romeo, Martin J
- Siemers, Eric R
- Vanderstichele, Hugo
- Coart, Els
- Konrad, Robert J
- Zajac, Joseph J
- Talbot, Jayne A
- Jensen, Hans F
- Sethuraman, Gopalan
- Demattos, Ronald B
- May, Patrick C
- Dean, Robert A
Producer: 20120111
In:
Journal of Alzheimer's disease : JAD vol. 26
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32.
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A plaque-specific antibody clears existing β-amyloid plaques in Alzheimer's disease mice. [electronic resource] by
- Demattos, Ronald B
- Lu, Jirong
- Tang, Ying
- Racke, Margaret M
- Delong, Cindy A
- Tzaferis, John A
- Hole, Justin T
- Forster, Beth M
- McDonnell, Peter C
- Liu, Feng
- Kinley, Robert D
- Jordan, William H
- Hutton, Michael L
Producer: 20130211
In:
Neuron vol. 76
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33.
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Safety and biomarker effects of solanezumab in patients with Alzheimer's disease. [electronic resource] by
- Farlow, Martin
- Arnold, Steven E
- van Dyck, Christopher H
- Aisen, Paul S
- Snider, B Joy
- Porsteinsson, Anton P
- Friedrich, Stuart
- Dean, Robert A
- Gonzales, Celedon
- Sethuraman, Gopalan
- DeMattos, Ronald B
- Mohs, Richard
- Paul, Steven M
- Siemers, Eric R
Producer: 20121113
In:
Alzheimer's & dementia : the journal of the Alzheimer's Association vol. 8
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34.
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TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques. [electronic resource] by
- Wang, Yaming
- Ulland, Tyler K
- Ulrich, Jason D
- Song, Wilbur
- Tzaferis, John A
- Hole, Justin T
- Yuan, Peng
- Mahan, Thomas E
- Shi, Yang
- Gilfillan, Susan
- Cella, Marina
- Grutzendler, Jaime
- DeMattos, Ronald B
- Cirrito, John R
- Holtzman, David M
- Colonna, Marco
Producer: 20170721
In:
The Journal of experimental medicine vol. 213
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35.
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ABCG1 influences the brain cholesterol biosynthetic pathway but does not affect amyloid precursor protein or apolipoprotein E metabolism in vivo. [electronic resource] by
- Burgess, Braydon L
- Parkinson, Pamela F
- Racke, Margaret M
- Hirsch-Reinshagen, Veronica
- Fan, Jianjia
- Wong, Charmaine
- Stukas, Sophie
- Theroux, Louise
- Chan, Jeniffer Y
- Donkin, James
- Wilkinson, Anna
- Balik, Danielle
- Christie, Brian
- Poirier, Judes
- Lütjohann, Dieter
- Demattos, Ronald B
- Wellington, Cheryl L
Producer: 20080805
In:
Journal of lipid research vol. 49
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36.
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Human apoE isoforms differentially regulate brain amyloid-β peptide clearance. [electronic resource] by
- Castellano, Joseph M
- Kim, Jungsu
- Stewart, Floy R
- Jiang, Hong
- DeMattos, Ronald B
- Patterson, Bruce W
- Fagan, Anne M
- Morris, John C
- Mawuenyega, Kwasi G
- Cruchaga, Carlos
- Goate, Alison M
- Bales, Kelly R
- Paul, Steven M
- Bateman, Randall J
- Holtzman, David M
Producer: 20111025
In:
Science translational medicine vol. 3
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37.
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The cholesterol transporter ABCG1 modulates the subcellular distribution and proteolytic processing of beta-amyloid precursor protein. [electronic resource] by
- Tansley, Gavin H
- Burgess, Braydon L
- Bryan, Matt T
- Su, Yuan
- Hirsch-Reinshagen, Veronica
- Pearce, Jonathan
- Chan, Jeniffer Y
- Wilkinson, Anna
- Evans, Jeanette
- Naus, Kathryn E
- McIsaac, Sean
- Bromley, Kelley
- Song, Weihong
- Yang, Hsui-Chiung
- Wang, Nan
- DeMattos, Ronald B
- Wellington, Cheryl L
Producer: 20070622
In:
Journal of lipid research vol. 48
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38.
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Trial of Solanezumab for Mild Dementia Due to Alzheimer's Disease. [electronic resource] by
- Honig, Lawrence S
- Vellas, Bruno
- Woodward, Michael
- Boada, Mercè
- Bullock, Roger
- Borrie, Michael
- Hager, Klaus
- Andreasen, Niels
- Scarpini, Elio
- Liu-Seifert, Hong
- Case, Michael
- Dean, Robert A
- Hake, Ann
- Sundell, Karen
- Poole Hoffmann, Vicki
- Carlson, Christopher
- Khanna, Rashna
- Mintun, Mark
- DeMattos, Ronald
- Selzler, Katherine J
- Siemers, Eric
Producer: 20180208
In:
The New England journal of medicine vol. 378
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39.
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Exacerbation of cerebral amyloid angiopathy-associated microhemorrhage in amyloid precursor protein transgenic mice by immunotherapy is dependent on antibody recognition of deposited forms of amyloid beta. [electronic resource] by
- Racke, Margaret M
- Boone, Laura I
- Hepburn, Deena L
- Parsadainian, Maia
- Bryan, Matthew T
- Ness, Daniel K
- Piroozi, Kathy S
- Jordan, William H
- Brown, Donna D
- Hoffman, Wherly P
- Holtzman, David M
- Bales, Kelly R
- Gitter, Bruce D
- May, Patrick C
- Paul, Steven M
- DeMattos, Ronald B
Producer: 20050818
In:
The Journal of neuroscience : the official journal of the Society for Neuroscience vol. 25
Availability: No items available.
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40.
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Genome-wide RNAseq study of the molecular mechanisms underlying microglia activation in response to pathological tau perturbation in the rTg4510 tau transgenic animal model. [electronic resource] by
- Wang, Hong
- Li, Yupeng
- Ryder, John W
- Hole, Justin T
- Ebert, Philip J
- Airey, David C
- Qian, Hui-Rong
- Logsdon, Benjamin
- Fisher, Alice
- Ahmed, Zeshan
- Murray, Tracey K
- Cavallini, Annalisa
- Bose, Suchira
- Eastwood, Brian J
- Collier, David A
- Dage, Jeffrey L
- Miller, Bradley B
- Merchant, Kalpana M
- O'Neill, Michael J
- Demattos, Ronald B
Producer: 20190412
In:
Molecular neurodegeneration vol. 13
Availability: No items available.
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