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Models and Approaches Describing the Metabolism, Transport, and Toxicity of Drugs Administered by the Ocular Route. [electronic resource] by
- Dumouchel, Jennifer L
- Chemuturi, Nagendra
- Milton, Mark N
- Camenisch, Gian
- Chastain, James
- Walles, Markus
- Sasseville, Vito
- Gunduz, Mithat
- Iyer, Ganesh R
- Argikar, Upendra A
Producer: 20190312
In:
Drug metabolism and disposition: the biological fate of chemicals vol. 46
Availability: No items available.
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Comprehensive assessment of human pharmacokinetic prediction based on in vivo animal pharmacokinetic data, part 2: clearance. [electronic resource] by
- Lombardo, Franco
- Waters, Nigel J
- Argikar, Upendra A
- Dennehy, Michelle K
- Zhan, Jenny
- Gunduz, Mithat
- Harriman, Shawn P
- Berellini, Giuliano
- Liric Rajlic, Ivana
- Obach, R Scott
Producer: 20130730
In:
Journal of clinical pharmacology vol. 53
Availability: No items available.
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33.
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Comprehensive assessment of human pharmacokinetic prediction based on in vivo animal pharmacokinetic data, part 1: volume of distribution at steady state. [electronic resource] by
- Lombardo, Franco
- Waters, Nigel J
- Argikar, Upendra A
- Dennehy, Michelle K
- Zhan, Jenny
- Gunduz, Mithat
- Harriman, Shawn P
- Berellini, Giuliano
- Rajlic, Ivana Liric
- Obach, R Scott
Producer: 20130730
In:
Journal of clinical pharmacology vol. 53
Availability: No items available.
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34.
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Compound Property Optimization in Drug Discovery Using Quantitative Surface Sampling Micro Liquid Chromatography with Tandem Mass Spectrometry. [electronic resource] by
- Chen, Xiaohui
- Hatsis, Panos
- Judge, Joyce
- Argikar, Upendra A
- Ren, Xiaojun
- Sarber, Jason
- Mansfield, Keith
- Liang, Guiqing
- Amaral, Adam
- Catoire, Alexandre
- Bentley, Adam
- Ramos, Luis
- Moench, Paul
- Hintermann, Samuel
- Carcache, David
- Glick, Jim
- Flarakos, Jimmy
Producer: 20180822
In:
Analytical chemistry vol. 88
Availability: No items available.
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35.
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Structure based design of nicotinamide phosphoribosyltransferase (NAMPT) inhibitors from a phenotypic screen. [electronic resource] by
- Palacios, Daniel S
- Meredith, Erik
- Kawanami, Toshio
- Adams, Christopher
- Chen, Xin
- Darsigny, Veronique
- Geno, Erin
- Palermo, Mark
- Baird, Daniel
- Boynton, Geoffrey
- Busby, Scott A
- George, Elizabeth L
- Guy, Chantale
- Hewett, Jeffrey
- Tierney, Laryssa
- Thigale, Sachin
- Weihofen, Wilhelm
- Wang, Louis
- White, Nicole
- Yin, Ming
- Argikar, Upendra A
Producer: 20190530
In:
Bioorganic & medicinal chemistry letters vol. 28
Availability: No items available.
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36.
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Optimization of Allosteric With-No-Lysine (WNK) Kinase Inhibitors and Efficacy in Rodent Hypertension Models. [electronic resource] by
- Yamada, Ken
- Levell, Julian
- Yoon, Taeyong
- Kohls, Darcy
- Yowe, David
- Rigel, Dean F
- Imase, Hidetomo
- Yuan, Jun
- Yasoshima, Kayo
- DiPetrillo, Keith
- Monovich, Lauren
- Xu, Lingfei
- Zhu, Meicheng
- Kato, Mitsunori
- Jain, Monish
- Idamakanti, Neeraja
- Taslimi, Paul
- Kawanami, Toshio
- Argikar, Upendra A
- Kunjathoor, Vidya
- Xie, Xiaoling
- Yagi, Yukiko I
- Iwaki, Yuki
- Robinson, Zachary
- Park, Hyi-Man
Producer: 20170926
In:
Journal of medicinal chemistry vol. 60
Availability: No items available.
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37.
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Discovery of Highly Potent and Selective Small-Molecule Reversible Factor D Inhibitors Demonstrating Alternative Complement Pathway Inhibition in Vivo. [electronic resource] by
- Lorthiois, Edwige
- Anderson, Karen
- Vulpetti, Anna
- Rogel, Olivier
- Cumin, Frederic
- Ostermann, Nils
- Steinbacher, Stefan
- Mac Sweeney, Aengus
- Delgado, Omar
- Liao, Sha-Mei
- Randl, Stefan
- Rüdisser, Simon
- Dussauge, Solene
- Fettis, Kamal
- Kieffer, Laurence
- de Erkenez, Andrea
- Yang, Louis
- Hartwieg, Constanze
- Argikar, Upendra A
- La Bonte, Laura R
- Newton, Ronald
- Kansara, Viral
- Flohr, Stefanie
- Hommel, Ulrich
- Jaffee, Bruce
- Maibaum, Jürgen
Producer: 20170801
In:
Journal of medicinal chemistry vol. 60
Availability: No items available.
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38.
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Design, Synthesis, and Preclinical Characterization of Selective Factor D Inhibitors Targeting the Alternative Complement Pathway. [electronic resource] by
- Karki, Rajeshri G
- Powers, James
- Mainolfi, Nello
- Anderson, Karen
- Belanger, David B
- Liu, Donglei
- Ji, Nan
- Jendza, Keith
- Gelin, Christine F
- Mac Sweeney, Aengus
- Solovay, Catherine
- Delgado, Omar
- Crowley, Maura
- Liao, Sha-Mei
- Argikar, Upendra A
- Flohr, Stefanie
- La Bonte, Laura R
- Lorthiois, Edwige L
- Vulpetti, Anna
- Brown, Ann
- Long, Debby
- Prentiss, Melissa
- Gradoux, Nathalie
- de Erkenez, Andrea
- Cumin, Frederic
- Adams, Christopher
- Jaffee, Bruce
- Mogi, Muneto
Producer: 20200622
In:
Journal of medicinal chemistry vol. 62
Availability: No items available.
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39.
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Small-molecule factor B inhibitor for the treatment of complement-mediated diseases. [electronic resource] by
- Schubart, Anna
- Anderson, Karen
- Mainolfi, Nello
- Sellner, Holger
- Ehara, Takeru
- Adams, Christopher M
- Mac Sweeney, Aengus
- Liao, Sha-Mei
- Crowley, Maura
- Littlewood-Evans, Amanda
- Sarret, Sophie
- Wieczorek, Grazyna
- Perrot, Ludovic
- Dubost, Valérie
- Flandre, Thierry
- Zhang, Yuzhou
- Smith, Richard J H
- Risitano, Antonio M
- Karki, Rajeshri G
- Zhang, Chun
- Valeur, Eric
- Sirockin, Finton
- Gerhartz, Bernd
- Erbel, Paulus
- Hughes, Nicola
- Smith, Thomas M
- Cumin, Frederic
- Argikar, Upendra A
- Haraldsson, Börje
- Mogi, Muneto
- Sedrani, Richard
- Wiesmann, Christian
- Jaffee, Bruce
- Maibaum, Jürgen
- Flohr, Stefanie
- Harrison, Richard
- Eder, Jörg
Producer: 20200323
In:
Proceedings of the National Academy of Sciences of the United States of America vol. 116
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40.
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Discovery of 4-((2 [electronic resource] by
- Mainolfi, Nello
- Ehara, Takeru
- Karki, Rajeshri G
- Anderson, Karen
- Mac Sweeney, Aengus
- Liao, Sha-Mei
- Argikar, Upendra A
- Jendza, Keith
- Zhang, Chun
- Powers, James
- Klosowski, Daniel W
- Crowley, Maura
- Kawanami, Toshio
- Ding, Jian
- April, Myriam
- Forster, Cornelia
- Serrano-Wu, Michael
- Capparelli, Michael
- Ramqaj, Rrezarta
- Solovay, Catherine
- Cumin, Frederic
- Smith, Thomas M
- Ferrara, Luciana
- Lee, Wendy
- Long, Debby
- Prentiss, Melissa
- De Erkenez, Andrea
- Yang, Louis
- Liu, Fang
- Sellner, Holger
- Sirockin, Finton
- Valeur, Eric
- Erbel, Paulus
- Ostermeier, Daniela
- Ramage, Paul
- Gerhartz, Bernd
- Schubart, Anna
- Flohr, Stefanie
- Gradoux, Nathalie
- Feifel, Roland
- Vogg, Barbara
- Wiesmann, Christian
- Maibaum, Jürgen
- Eder, Jörg
- Sedrani, Richard
- Harrison, Richard A
- Mogi, Muneto
- Jaffee, Bruce D
- Adams, Christopher M
Producer: 20201112
In:
Journal of medicinal chemistry vol. 63
Availability: No items available.
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