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Kinetic analyses reveal potent and early blockade of hepatitis C virus assembly by NS5A inhibitors. [electronic resource] by
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- Feng, Zongdi
- Lahser, Frederick
- Asante-Appiah, Ernest
- Neddermann, Petra
- De Francesco, Raffaele
- Howe, Anita Y
- Lemon, Stanley M
Producer: 20140911
In:
Gastroenterology vol. 147
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The Combination of Grazoprevir, a Hepatitis C Virus (HCV) NS3/4A Protease Inhibitor, and Elbasvir, an HCV NS5A Inhibitor, Demonstrates a High Genetic Barrier to Resistance in HCV Genotype 1a Replicons. [electronic resource] by
- Lahser, Frederick C
- Bystol, Karin
- Curry, Stephanie
- McMonagle, Patricia
- Xia, Ellen
- Ingravallo, Paul
- Chase, Robert
- Liu, Rong
- Black, Todd
- Hazuda, Daria
- Howe, Anita Y M
- Asante-Appiah, Ernest
Producer: 20170905
In:
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Conformation-assisted inhibition of protein-tyrosine phosphatase-1B elicits inhibitor selectivity over T-cell protein-tyrosine phosphatase. [electronic resource] by
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- Patel, Sangita
- Desponts, Caroline
- Taylor, Jillian M
- Lau, Cheuk
- Dufresne, Claude
- Therien, Michel
- Friesen, Rick
- Becker, Joseph W
- Leblanc, Yves
- Kennedy, Brian P
- Scapin, Giovanna
Producer: 20060510
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The structure of PTP-1B in complex with a peptide inhibitor reveals an alternative binding mode for bisphosphonates. [electronic resource] by
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- Roy, Patrick
- Wang, Qingping
- Patel, Vira
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- Ramachandran, Chidambaram
- Becker, Joseph W
- Leblanc, Yves
- Kennedy, Brian P
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In:
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Evolutionary pathways to NS5A inhibitor resistance in genotype 1 hepatitis C virus. [electronic resource] by
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- Hu, Fengyu
- Benzine, Tiffany
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- Asante-Appiah, Ernest
- Howe, Anita Y M
- Swanstrom, Ronald
- Lemon, Stanley M
Producer: 20191003
In:
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Conotruncal Heart Defect Repair in Sub-Saharan Africa: Remarkable Outcomes Despite Poor Access to Treatment. [electronic resource] by
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- Tamatey, Martin M
- Adzamli, Innocent
- Akyaa-Yao, Nana
- Gyan, Kofi B
- Ofosu-Appiah, Ernest
- Kotei, David
Producer: 20170605
In:
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Efficacy of elbasvir and grazoprevir in participants with hepatitis C virus genotype 4 infection: A pooled analysis. [electronic resource] by
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- Robertson, Michael
- Hwang, Peggy
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- Wahl, Janice
- Nguyen, Bach-Yen
- Barr, Eliav
- Talwani, Rohit
- Serfaty, Lawrence
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In:
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- Asante-Appiah, Ernest
- Liu, Rong
- Curry, Stephanie
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- Lahser, Frederick
- Bystol, Karin
- Chase, Robert
- Black, Stuart
- Ferrari, Eric
- Ingravallo, Paul
- Tong, Ling
- Yu, Wensheng
- Kozlowski, Joseph
Producer: 20191008
In:
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The development of potent non-peptidic PTP-1B inhibitors. [electronic resource] by
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- Cromlish, Wanda
- Boie, Yves
- Forghani, Farnaz
- Desmarais, Sylvie
- Wang, Qingping
- Skorey, Kathryn
- Waddleton, Deena
- Ramachandran, Chidambaram
- Kennedy, Brian P
- Xu, Lijing
- Gordon, Robert
- Chan, Chi Chung
- Leblanc, Yves
Producer: 20040928
In:
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The structural basis for the selectivity of benzotriazole inhibitors of PTP1B. [electronic resource] by
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- Waddleton, Deena
- Skorey, Kathryn
- Cromlish, Wanda
- Bayly, Christopher
- Therien, Michel
- Gauthier, Jacques Yves
- Li, Chun Sing
- Lau, Cheuk K
- Ramachandran, Chidambaram
- Kennedy, Brian P
- Asante-Appiah, Ernest
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In:
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Structure based design of a series of potent and selective non peptidic PTP-1B inhibitors. [electronic resource] by
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- Li, Chun Sing
- Therien, Michel
- Asante-Appiah, Ernest
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- Boie, Yves
- Forghani, Farnaz
- Desmarais, Sylvie
- Wang, Qingping
- Skorey, Kathryn
- Waddleton, Deena
- Payette, Paul
- Ramachandran, Chidambaram
- Kennedy, Brian P
- Scapin, Giovana
Producer: 20040928
In:
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Safety and efficacy of elbasvir/grazoprevir in Asian participants with hepatitis C virus genotypes 1 and 4 infection. [electronic resource] by
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- Kumada, Hiromitsu
- Perumalswami, Ponni V
- Tanwandee, Tawesak
- Cheng, Wendy
- Heo, Jeong
- Cheng, Pin-Nan
- Hwang, Peggy
- Mu, Sheng Mei
- Zhao, Xu Min
- Asante-Appiah, Ernest
- Caro, Luzelena
- Hanna, George J
- Robertson, Michael N
- Haber, Barbara A
- Talwani, Rohit
Producer: 20200302
In:
Journal of gastroenterology and hepatology vol. 34
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Discovery of Chromane Containing Hepatitis C Virus (HCV) NS5A Inhibitors with Improved Potency against Resistance-Associated Variants. [electronic resource] by
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- Hu, Bin
- Zhong, Bin
- Hao, Jinglai
- Ji, Tao
- Zan, Shuai
- Coburn, Craig A
- Selyutin, Oleg
- Chen, Lei
- Rokosz, Laura
- Agrawal, Sony
- Liu, Rong
- Curry, Stephanie
- McMonagle, Patricia
- Ingravallo, Paul
- Asante-Appiah, Ernest
- Chen, Shiying
- Kozlowski, Joseph A
Producer: 20170613
In:
Journal of medicinal chemistry vol. 59
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Efficacy and safety of ruzasvir 60 mg and uprifosbuvir 450 mg for 12 weeks in adults with chronic hepatitis C virus genotype 1, 2, 3, 4 or 6 infection. [electronic resource] by
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- Poordad, Fred
- Anderson, Leah J
- Vesay, Michelle
- Kelly, Michelle M
- Liu, Hong
- Gao, Wei
- Fernsler, Doreen
- Asante-Appiah, Ernest
- Robertson, Michael N
- Hanna, George J
- Barr, Eliav
- Butterton, Joan
- Kowdley, Kris V
- Hassanein, Tarek
- Sahota, Amandeep
- Gordon, Stuart C
- Yeh, Wendy W
Producer: 20200722
In:
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In vitro characterization of MK-1439, a novel HIV-1 nonnucleoside reverse transcriptase inhibitor. [electronic resource] by
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- Feng, Meizhen
- Falgueyret, Jean-Pierre
- Tawa, Paul
- Witmer, Marc
- DiStefano, Daniel
- Li, Yuan
- Burch, Jason
- Sachs, Nancy
- Lu, Meiqing
- Cauchon, Elizabeth
- Campeau, Louis-Charles
- Grobler, Jay
- Yan, Youwei
- Ducharme, Yves
- Côté, Bernard
- Asante-Appiah, Ernest
- Hazuda, Daria J
- Miller, Michael D
Producer: 20141028
In:
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Efficacy and safety of elbasvir/grazoprevir and sofosbuvir/pegylated interferon/ribavirin: A phase III randomized controlled trial. [electronic resource] by
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- Horvath, Gabor
- Halota, Waldemar
- Ruiz-Tapiador, Juan Arenas
- Streinu-Cercel, Anca
- Jancoriene, Ligita
- Werling, Klara
- Kileng, Hege
- Koklu, Seyfettin
- Gerstoft, Jan
- Urbanek, Petr
- Flisiak, Robert
- Leiva, Rafael
- Kazenaite, Edita
- Prinzing, Renate
- Patel, Sushma
- Qiu, Jingjun
- Asante-Appiah, Ernest
- Wahl, Janice
- Nguyen, Bach-Yen
- Barr, Eliav
- Platt, Heather L
Producer: 20180419
In:
Journal of hepatology vol. 65
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Elbasvir/grazoprevir and sofosbuvir for hepatitis C virus genotype 3 infection with compensated cirrhosis: A randomized trial. [electronic resource] by
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- Agarwal, Kosh
- Cramp, Matthew E
- Moreea, Sulleman
- Barclay, Stephen
- Collier, Jane
- Brown, Ashley S
- Ryder, Stephen D
- Ustianowski, Andrew
- Forton, Daniel M
- Fox, Ray
- Gordon, Fiona
- Rosenberg, William M
- Mutimer, David J
- Du, Jiejun
- Gilbert, Christopher L
- Asante-Appiah, Ernest
- Wahl, Janice
- Robertson, Michael N
- Barr, Eliav
- Haber, Barbara
Producer: 20181023
In:
Hepatology (Baltimore, Md.) vol. 67
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Alternative core development around the tetracyclic indole class of HCV NS5A inhibitors. [electronic resource] by
- Tong, Ling
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- Coburn, Craig A
- Meinke, Peter T
- Nair, Anilkumar G
- Dwyer, Michael P
- Chen, Lei
- Selyutin, Oleg
- Rosenblum, Stuart B
- Jiang, Yueheng
- Fells, James
- Hu, Bin
- Zhong, Bin
- Soll, Richard M
- Liu, Rong
- Agrawal, Sony
- Xia, Ellen
- Zhai, Ying
- Kong, Rong
- Ingravallo, Paul
- Nomeir, Amin
- Asante-Appiah, Ernest
- Kozlowski, Joseph A
Producer: 20170808
In:
Bioorganic & medicinal chemistry letters vol. 26
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39.
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Discovery of MK-6169, a Potent Pan-Genotype Hepatitis C Virus NS5A Inhibitor with Optimized Activity against Common Resistance-Associated Substitutions. [electronic resource] by
- Yu, Wensheng
- Tong, Ling
- Selyutin, Oleg
- Chen, Lei
- Hu, Bin
- Zhong, Bin
- Hao, Jinglai
- Ji, Tao
- Zan, Shuai
- Yin, Jingjun
- Ruck, Rebecca T
- Curry, Stephanie
- McMonagle, Patricia
- Agrawal, Sony
- Rokosz, Laura
- Carr, Donna
- Ingravallo, Paul
- Bystol, Karin
- Lahser, Frederick
- Liu, Rong
- Chen, Shiying
- Feng, Kung-I
- Cartwright, Mark
- Asante-Appiah, Ernest
- Kozlowski, Joseph A
Producer: 20190528
In:
Journal of medicinal chemistry vol. 61
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40.
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MK-8325: A silyl proline-containing NS5A inhibitor with pan-genotype activity for treatment of HCV. [electronic resource] by
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- Zeng, Qingbei
- Selyutin, Oleg
- Rosenblum, Stuart B
- Jiang, Yueheng
- Yang, De-Yi
- Keertikar, Kerry
- Zhou, Guowei
- Dwyer, Michael
- Kim, Seong Heon
- Shankar, Bandarpalle
- Yu, Wensheng
- Tong, Ling
- Chen, Lei
- Mazzola, Robert
- Caldwell, John
- Tang, Haiqun
- Agrawal, Sony
- Liu, Rong
- Kong, Rong
- Ingravallo, Paul
- Xia, Ellen
- Zhai, Ying
- Nomeir, Amin
- Asante-Appiah, Ernest
- Kozlowski, Joseph A
Producer: 20181227
In:
Bioorganic & medicinal chemistry letters vol. 28
Availability: No items available.
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