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Novel inhibitors of DNA gyrase: 3D structure based biased needle screening, hit validation by biophysical methods, and 3D guided optimization. A promising alternative to random screening. [electronic resource] by
- Boehm, H J
- Boehringer, M
- Bur, D
- Gmuender, H
- Huber, W
- Klaus, W
- Kostrewa, D
- Kuehne, H
- Luebbers, T
- Meunier-Keller, N
- Mueller, F
Producer: 20000803
In:
Journal of medicinal chemistry vol. 43
Availability: No items available.
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1807.
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The high-resolution crystal structure of a 24-kDa gyrase B fragment from E. coli complexed with one of the most potent coumarin inhibitors, clorobiocin. [electronic resource] by
- Tsai, F T
- Singh, O M
- Skarzynski, T
- Wonacott, A J
- Weston, S
- Tucker, A
- Pauptit, R A
- Breeze, A L
- Poyser, J P
- O'Brien, R
- Ladbury, J E
- Wigley, D B
Producer: 19970818
In:
Proteins vol. 28
Availability: No items available.
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