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1581.
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1582.
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1583.
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Synthesis and biological evaluation of 3-heterocyclyl-7,8,9,10-tetrahydro-(7,10-ethano)-1,2,4-triazolo[3,4-a]phthalazines and analogues as subtype-selective inverse agonists for the GABA(A)alpha5 benzodiazepine binding site. [electronic resource] by
- Street, Leslie J
- Sternfeld, Francine
- Jelley, Richard A
- Reeve, Austin J
- Carling, Robert W
- Moore, Kevin W
- McKernan, Ruth M
- Sohal, Bindi
- Cook, Susan
- Pike, Andrew
- Dawson, Gerard R
- Bromidge, Frances A
- Wafford, Keith A
- Seabrook, Guy R
- Thompson, Sally A
- Marshall, George
- Pillai, Goplan V
- Castro, José L
- Atack, John R
- MacLeod, Angus M
Producer: 20040802
In:
Journal of medicinal chemistry vol. 47
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1584.
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1585.
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1586.
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Phase II, open-label, randomized, multicenter study comparing the efficacy and safety of olaparib, a poly (ADP-ribose) polymerase inhibitor, and pegylated liposomal doxorubicin in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer. [electronic resource] by
- Kaye, Stan B
- Lubinski, Jan
- Matulonis, Ursula
- Ang, Joo Ern
- Gourley, Charlie
- Karlan, Beth Y
- Amnon, Amit
- Bell-McGuinn, Katherine M
- Chen, Lee-May
- Friedlander, Michael
- Safra, Tamar
- Vergote, Ignace
- Wickens, Mark
- Lowe, Elizabeth S
- Carmichael, James
- Kaufman, Bella
Producer: 20120508
In:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology vol. 30
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1587.
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Vatalanib for metastatic gastrointestinal stromal tumour (GIST) resistant to imatinib: final results of a phase II study. [electronic resource] by
- Joensuu, H
- De Braud, F
- Grignagni, G
- De Pas, T
- Spitalieri, G
- Coco, P
- Spreafico, C
- Boselli, S
- Toffalorio, F
- Bono, P
- Jalava, T
- Kappeler, C
- Aglietta, M
- Laurent, D
- Casali, P G
Producer: 20110721
In:
British journal of cancer vol. 104
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1588.
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miR-182-mediated downregulation of BRCA1 impacts DNA repair and sensitivity to PARP inhibitors. [electronic resource] by
- Moskwa, Patryk
- Buffa, Francesca M
- Pan, Yunfeng
- Panchakshari, Rohit
- Gottipati, Ponnari
- Muschel, Ruth J
- Beech, John
- Kulshrestha, Ritu
- Abdelmohsen, Kotb
- Weinstock, David M
- Gorospe, Myriam
- Harris, Adrian L
- Helleday, Thomas
- Chowdhury, Dipanjan
Producer: 20110304
In:
Molecular cell vol. 41
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1589.
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PARP1 is required for chromosomal translocations. [electronic resource] by
- Wray, Justin
- Williamson, Elizabeth A
- Singh, Sudha B
- Wu, Yuehan
- Cogle, Christopher R
- Weinstock, David M
- Zhang, Yu
- Lee, Suk-Hee
- Zhou, Daohong
- Shao, Lijian
- Hauer-Jensen, Martin
- Pathak, Rupak
- Klimek, Virginia
- Nickoloff, Jac A
- Hromas, Robert
Producer: 20130723
In:
Blood vol. 121
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1590.
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Phase II study of olaparib in patients with refractory Ewing sarcoma following failure of standard chemotherapy. [electronic resource] by
- Choy, Edwin
- Butrynski, James E
- Harmon, David C
- Morgan, Jeffrey A
- George, Suzanne
- Wagner, Andrew J
- D'Adamo, David
- Cote, Gregory M
- Flamand, Yael
- Benes, Cyril H
- Haber, Daniel A
- Baselga, Jose M
- Demetri, George D
Producer: 20150709
In:
BMC cancer vol. 14
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1591.
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1592.
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Design and synthesis of 4-benzyl-1-(2H)-phthalazinone derivatives as novel androgen receptor antagonists. [electronic resource] by
- Inoue, Kazumi
- Urushibara, Ko
- Kanai, Misae
- Yura, Kei
- Fujii, Shinya
- Ishigami-Yuasa, Mari
- Hashimoto, Yuichi
- Mori, Shuichi
- Kawachi, Emiko
- Matsumura, Mio
- Hirano, Tomoya
- Kagechika, Hiroyuki
- Tanatani, Aya
Producer: 20160614
In:
European journal of medicinal chemistry vol. 102
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1593.
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1594.
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1595.
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1596.
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CXCR2-Expressing Tumor Cells Drive Vascular Mimicry in Antiangiogenic Therapy-Resistant Glioblastoma. [electronic resource] by
- Angara, Kartik
- Borin, Thaiz F
- Rashid, Mohammad H
- Lebedyeva, Iryna
- Ara, Roxan
- Lin, Ping-Chang
- Iskander, Asm
- Bollag, Roni J
- Achyut, Bhagelu R
- Arbab, Ali S
Producer: 20190128
In:
Neoplasia (New York, N.Y.) vol. 20
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