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1481.
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Chemogenomic profiling provides insights into the limited activity of irreversible EGFR Inhibitors in tumor cells expressing the T790M EGFR resistance mutation. [electronic resource] by
- Sos, Martin L
- Rode, Haridas B
- Heynck, Stefanie
- Peifer, Martin
- Fischer, Florian
- Klüter, Sabine
- Pawar, Vijaykumar G
- Reuter, Cecile
- Heuckmann, Johannes M
- Weiss, Jonathan
- Ruddigkeit, Lars
- Rabiller, Matthias
- Koker, Mirjam
- Simard, Jeffrey R
- Getlik, Matthäus
- Yuza, Yuki
- Chen, Tzu-Hsiu
- Greulich, Heidi
- Thomas, Roman K
- Rauh, Daniel
Producer: 20100309
In:
Cancer research vol. 70
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1482.
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Splice-site mutations in the axonemal outer dynein arm docking complex gene CCDC114 cause primary ciliary dyskinesia. [electronic resource] by
- Onoufriadis, Alexandros
- Paff, Tamara
- Antony, Dinu
- Shoemark, Amelia
- Micha, Dimitra
- Kuyt, Bertus
- Schmidts, Miriam
- Petridi, Stavroula
- Dankert-Roelse, Jeanette E
- Haarman, Eric G
- Daniels, Johannes M A
- Emes, Richard D
- Wilson, Robert
- Hogg, Claire
- Scambler, Peter J
- Chung, Eddie M K
- Pals, Gerard
- Mitchison, Hannah M
Producer: 20130312
In:
American journal of human genetics vol. 92
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1483.
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Discovery and resupply of pharmacologically active plant-derived natural products: A review. [electronic resource] by
- Atanasov, Atanas G
- Waltenberger, Birgit
- Pferschy-Wenzig, Eva-Maria
- Linder, Thomas
- Wawrosch, Christoph
- Uhrin, Pavel
- Temml, Veronika
- Wang, Limei
- Schwaiger, Stefan
- Heiss, Elke H
- Rollinger, Judith M
- Schuster, Daniela
- Breuss, Johannes M
- Bochkov, Valery
- Mihovilovic, Marko D
- Kopp, Brigitte
- Bauer, Rudolf
- Dirsch, Verena M
- Stuppner, Hermann
Producer: 20160916
In:
Biotechnology advances vol. 33
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1484.
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Mutations in PIH1D3 Cause X-Linked Primary Ciliary Dyskinesia with Outer and Inner Dynein Arm Defects. [electronic resource] by
- Paff, Tamara
- Loges, Niki T
- Aprea, Isabella
- Wu, Kaman
- Bakey, Zeineb
- Haarman, Eric G
- Daniels, Johannes M A
- Sistermans, Erik A
- Bogunovic, Natalija
- Dougherty, Gerard W
- Höben, Inga M
- Große-Onnebrink, Jörg
- Matter, Anja
- Olbrich, Heike
- Werner, Claudius
- Pals, Gerard
- Schmidts, Miriam
- Omran, Heymut
- Micha, Dimitra
Producer: 20170524
In:
American journal of human genetics vol. 100
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1485.
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Reducing GBA2 Activity Ameliorates Neuropathology in Niemann-Pick Type C Mice. [electronic resource] by
- Marques, André R A
- Aten, Jan
- Ottenhoff, Roelof
- van Roomen, Cindy P A A
- Herrera Moro, Daniela
- Claessen, Nike
- Vinueza Veloz, María Fernanda
- Zhou, Kuikui
- Lin, Zhanmin
- Mirzaian, Mina
- Boot, Rolf G
- De Zeeuw, Chris I
- Overkleeft, Herman S
- Yildiz, Yildiz
- Aerts, Johannes M F G
Producer: 20160506
In:
PloS one vol. 10
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1486.
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Transglycosidase activity of chitotriosidase: improved enzymatic assay for the human macrophage chitinase. [electronic resource] by
- Aguilera, Begoña
- Ghauharali-van der Vlugt, Karen
- Helmond, Mariette T J
- Out, Jos M M
- Donker-Koopman, Wilma E
- Groener, Johanna E M
- Boot, Rolf G
- Renkema, G Herma
- van der Marel, Gijs A
- van Boom, Jacques H
- Overkleeft, Hermen S
- Aerts, Johannes M F G
Producer: 20031203
In:
The Journal of biological chemistry vol. 278
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1487.
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Effects of erythropoietin on cycling performance of well trained cyclists: a double-blind, randomised, placebo-controlled trial. [electronic resource] by
- Heuberger, Jules A A C
- Rotmans, Joris I
- Gal, Pim
- Stuurman, Frederik E
- van 't Westende, Juliëtte
- Post, Titiaan E
- Daniels, Johannes M A
- Moerland, Matthijs
- van Veldhoven, Peter L J
- de Kam, Marieke L
- Ram, Herman
- de Hon, Olivier
- Posthuma, Jelle J
- Burggraaf, Jacobus
- Cohen, Adam F
Producer: 20180312
In:
The Lancet. Haematology vol. 4
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1488.
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Effects of silver nanoparticles (NM-300K) on Lumbricus rubellus earthworms and particle characterization in relevant test matrices including soil. [electronic resource] by
- van der Ploeg, Merel J C
- Handy, Richard D
- Waalewijn-Kool, Pauline L
- van den Berg, Johannes H J
- Herrera Rivera, Zahira E
- Bovenschen, Jan
- Molleman, Bastiaan
- Baveco, Johannes M
- Tromp, Peter
- Peters, Ruud J B
- Koopmans, Gerwin F
- Rietjens, Ivonne M C M
- van den Brink, Nico W
Producer: 20140527
In:
Environmental toxicology and chemistry vol. 33
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1489.
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Species-specific differences in nonlysosomal glucosylceramidase GBA2 function underlie locomotor dysfunction arising from loss-of-function mutations. [electronic resource] by
- Woeste, Marina A
- Stern, Sina
- Raju, Diana N
- Grahn, Elena
- Dittmann, Dominik
- Gutbrod, Katharina
- Dörmann, Peter
- Hansen, Jan N
- Schonauer, Sophie
- Marx, Carina E
- Hamzeh, Hussein
- Körschen, Heinz G
- Aerts, Johannes M F G
- Bönigk, Wolfgang
- Endepols, Heike
- Sandhoff, Roger
- Geyer, Matthias
- Berger, Thomas K
- Bradke, Frank
- Wachten, Dagmar
Producer: 20190530
In:
The Journal of biological chemistry vol. 294
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1490.
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HIF prolyl hydroxylase inhibition protects skeletal muscle from eccentric contraction-induced injury. [electronic resource] by
- Billin, Andrew N
- Honeycutt, Samuel E
- McDougal, Alan V
- Kerr, Jaclyn P
- Chen, Zhe
- Freudenberg, Johannes M
- Rajpal, Deepak K
- Luo, Guizhen
- Kramer, Henning Fritz
- Geske, Robert S
- Fang, Frank
- Yao, Bert
- Clark, Richard V
- Lepore, John
- Cobitz, Alex
- Miller, Ram
- Nosaka, Kazunori
- Hinken, Aaron C
- Russell, Alan J
Producer: 20190211
In:
Skeletal muscle vol. 8
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1491.
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Correction to: HIF prolyl hydroxylase inhibition protects skeletal muscle from eccentric contraction induced injury. [electronic resource] by
- Billin, Andrew N
- Honeycutt, Samuel E
- McDougal, Alan V
- Kerr, Jaclyn P
- Chen, Zhe
- Freudenberg, Johannes M
- Rajpal, Deepak K
- Luo, Guizhen
- Kramer, Henning Fritz
- Geske, Robert S
- Fang, Frank
- Yao, Bert
- Clark, Richard V
- Lepore, John
- Cobitz, Alex
- Miller, Ram
- Nosaka, Kazunori
- Hinken, Aaron C
- Russell, Alan J
Publication details: Skeletal muscle 12 2018
In:
Skeletal muscle vol. 8
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1492.
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New Irreversible α-l-Iduronidase Inhibitors and Activity-Based Probes. [electronic resource] by
- Artola, Marta
- Kuo, Chi-Lin
- McMahon, Stephen A
- Oehler, Verena
- Hansen, Thomas
- van der Lienden, Martijn
- He, Xu
- van den Elst, Hans
- Florea, Bogdan I
- Kermode, Allison R
- van der Marel, Gijsbert A
- Gloster, Tracey M
- Codée, Jeroen D C
- Overkleeft, Herman S
- Aerts, Johannes M F G
Producer: 20190111
In:
Chemistry (Weinheim an der Bergstrasse, Germany) vol. 24
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1493.
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Visualization of Active Glucocerebrosidase in Rodent Brain with High Spatial Resolution following In Situ Labeling with Fluorescent Activity Based Probes. [electronic resource] by
- Herrera Moro Chao, Daniela
- Kallemeijn, Wouter W
- Marques, Andre R A
- Orre, Marie
- Ottenhoff, Roelof
- van Roomen, Cindy
- Foppen, Ewout
- Renner, Maria C
- Moeton, Martina
- van Eijk, Marco
- Boot, Rolf G
- Kamphuis, Willem
- Hol, Elly M
- Aten, Jan
- Overkleeft, Hermen S
- Kalsbeek, Andries
- Aerts, Johannes M F G
Producer: 20160609
In:
PloS one vol. 10
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1494.
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Wnt Pathway in Bone Repair and Regeneration - What Do We Know So Far. [electronic resource] by
- Houschyar, Khosrow S
- Tapking, Christian
- Borrelli, Mimi R
- Popp, Daniel
- Duscher, Dominik
- Maan, Zeshaan N
- Chelliah, Malcolm P
- Li, Jingtao
- Harati, Kamran
- Wallner, Christoph
- Rein, Susanne
- Pförringer, Dominik
- Reumuth, Georg
- Grieb, Gerrit
- Mouraret, Sylvain
- Dadras, Mehran
- Wagner, Johannes M
- Cha, Jungul Y
- Siemers, Frank
- Lehnhardt, Marcus
- Behr, Björn
Publication details: Frontiers in cell and developmental biology 2018
In:
Frontiers in cell and developmental biology vol. 6
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1495.
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Elevated globotriaosylsphingosine is a hallmark of Fabry disease. [electronic resource] by
- Aerts, Johannes M
- Groener, Johanna E
- Kuiper, Sijmen
- Donker-Koopman, Wilma E
- Strijland, Anneke
- Ottenhoff, Roelof
- van Roomen, Cindy
- Mirzaian, Mina
- Wijburg, Frits A
- Linthorst, Gabor E
- Vedder, Anouk C
- Rombach, Saskia M
- Cox-Brinkman, Josanne
- Somerharju, Pentti
- Boot, Rolf G
- Hollak, Carla E
- Brady, Roscoe O
- Poorthuis, Ben J
Producer: 20080429
In:
Proceedings of the National Academy of Sciences of the United States of America vol. 105
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1496.
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Dual-action lipophilic iminosugar improves glycemic control in obese rodents by reduction of visceral glycosphingolipids and buffering of carbohydrate assimilation. [electronic resource] by
- Wennekes, Tom
- Meijer, Alfred J
- Groen, Albert K
- Boot, Rolf G
- Groener, Johanna E
- van Eijk, Marco
- Ottenhoff, Roelof
- Bijl, Nora
- Ghauharali, Karen
- Song, Hang
- O'Shea, Tom J
- Liu, Hanlan
- Yew, Nelson
- Copeland, Diane
- van den Berg, Richard J
- van der Marel, Gijsbert A
- Overkleeft, Herman S
- Aerts, Johannes M
Producer: 20100302
In:
Journal of medicinal chemistry vol. 53
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1497.
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Synthesis and Evaluation of Hybrid Structures Composed of Two Glucosylceramide Synthase Inhibitors. [electronic resource] by
- van den Berg, Richard J B H N
- van Rijssel, Erwin R
- Ferraz, Maria Joao
- Houben, Judith
- Strijland, Anneke
- Donker-Koopman, Wilma E
- Wennekes, Tom
- Bonger, Kimberly M
- Ghisaidoobe, Amar B T
- Hoogendoorn, Sascha
- van der Marel, Gijsbert A
- Codée, Jeroen D C
- Overkleeft, Herman S
- Aerts, Johannes M F G
Producer: 20161014
In:
ChemMedChem vol. 10
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1498.
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Stabilization of Glucocerebrosidase by Active Site Occupancy. [electronic resource] by
- Ben Bdira, Fredj
- Kallemeijn, Wouter W
- Oussoren, Saskia V
- Scheij, Saskia
- Bleijlevens, Boris
- Florea, Bogdan I
- van Roomen, Cindy P A A
- Ottenhoff, Roelof
- van Kooten, Marielle J F M
- Walvoort, Marthe T C
- Witte, Martin D
- Boot, Rolf G
- Ubbink, Marcellus
- Overkleeft, Herman S
- Aerts, Johannes M F G
Producer: 20180207
In:
ACS chemical biology vol. 12
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1499.
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EUROmediCAT signal detection: a systematic method for identifying potential teratogenic medication. [electronic resource] by
- Luteijn, Johannes M
- Morris, Joan K
- Garne, Ester
- Given, Joanne
- de Jong-van den Berg, Lolkje
- Addor, Marie-Claude
- Bakker, Marian
- Barisic, Ingeborg
- Gatt, Miriam
- Klungsoyr, Kari
- Latos-Bielenska, Anna
- Lelong, Nathalie
- Nelen, Vera
- Neville, Amanda
- O'Mahony, Mary
- Pierini, Anna
- Tucker, David
- de Walle, Hermien
- Wiesel, Awi
- Loane, Maria
- Dolk, Helen
Producer: 20180108
In:
British journal of clinical pharmacology vol. 82
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1500.
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Xenotransplantation of Human Cardiomyocyte Progenitor Cells Does Not Improve Cardiac Function in a Porcine Model of Chronic Ischemic Heart Failure. Results from a Randomized, Blinded, Placebo Controlled Trial. [electronic resource] by
- Jansen of Lorkeers, Sanne J
- Gho, Johannes M I H
- Koudstaal, Stefan
- van Hout, Gerardus P J
- Zwetsloot, Peter Paul M
- van Oorschot, Joep W M
- van Eeuwijk, Esther C M
- Leiner, Tim
- Hoefer, Imo E
- Goumans, Marie-José
- Doevendans, Pieter A
- Sluijter, Joost P G
- Chamuleau, Steven A J
Producer: 20160622
In:
PloS one vol. 10
Availability: No items available.
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