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LincRNA-p21 activates p21 in cis to promote Polycomb target gene expression and to enforce the G1/S checkpoint. [electronic resource] by
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- Soukup, Dylan
- Resnick, Rebecca
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- Lee, Jeannie T
- Sharp, Phillip A
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Mir-290-295 deficiency in mice results in partially penetrant embryonic lethality and germ cell defects. [electronic resource] by
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- Markoulaki, Styliani
- Fu, Dongdong
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- Sharp, Phillip A
- Page, David C
- Jaenisch, Rudolf
Producer: 20111027
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Proceedings of the National Academy of Sciences of the United States of America vol. 108
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Functional delivery of siRNA in mice using dendriworms. [electronic resource] by
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- Min, Dal-Hee
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- Zhu, Haihao
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- von Maltzahn, Geoffrey
- Harris, Todd J
- Xing, Deyin
- Woolfenden, Stephen D
- Sharp, Phillip A
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In:
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124.
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Enhancer Features that Drive Formation of Transcriptional Condensates. [electronic resource] by
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- Klein, Isaac A
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- Zamudio, Alicia V
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125.
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Divergent transcription of long noncoding RNA/mRNA gene pairs in embryonic stem cells. [electronic resource] by
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- Gupta, Sumeet
- Orlando, David A
- Guenther, Matthew G
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- Lin, Charles
- Sharp, Phillip A
- Giallourakis, Cosmas C
- Young, Richard A
Producer: 20130426
In:
Proceedings of the National Academy of Sciences of the United States of America vol. 110
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TAZ, a transcriptional modulator of mesenchymal stem cell differentiation. [electronic resource] by
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- Amsterdam, Adam
- Tian, Yu
- Kalmukova, Ralitsa
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- Benjamin, Thomas
- Spiegelman, Bruce M
- Sharp, Phillip A
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Producer: 20050826
In:
Science (New York, N.Y.) vol. 309
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127.
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Genome-wide CRISPR screen in a mouse model of tumor growth and metastasis. [electronic resource] by
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- Lee, Kyungheon
- Shi, Xi
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- Song, Jun
- Pan, Jen Q
- Weissleder, Ralph
- Lee, Hakho
- Zhang, Feng
- Sharp, Phillip A
Producer: 20150512
In:
Cell vol. 160
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128.
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Total Syntheses of the 3 [electronic resource] by
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- Sharp, Phillip P
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- Rihouey, Charly
- Kendrick, Amy
- Lan, Ping
- Banwell, Martin G
- Jackson, Colin J
- Fraser, Nicholas J
- Willis, Anthony C
- Ward, Jas S
Producer: 20200731
In:
The Journal of organic chemistry vol. 85
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129.
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Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters. [electronic resource] by
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- Erkeland, Stefan J
- Newman, Jamie
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- Crowley, Denise
- Stone, James R
- Jaenisch, Rudolf
- Sharp, Phillip A
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Producer: 20080325
In:
Cell vol. 132
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130.
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CRISPR-mediated direct mutation of cancer genes in the mouse liver. [electronic resource] by
- Xue, Wen
- Chen, Sidi
- Yin, Hao
- Tammela, Tuomas
- Papagiannakopoulos, Thales
- Joshi, Nikhil S
- Cai, Wenxin
- Yang, Gillian
- Bronson, Roderick
- Crowley, Denise G
- Zhang, Feng
- Anderson, Daniel G
- Sharp, Phillip A
- Jacks, Tyler
Producer: 20141112
In:
Nature vol. 514
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131.
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MicroRNA-responsive 'sensor' transgenes uncover Hox-like and other developmentally regulated patterns of vertebrate microRNA expression. [electronic resource] by
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- Obenauer, John
- Srineel, Jalagani
- Chaudhuri, Aadel
- Farzan-Kashani, Raphael
- Zuker, Michael
- Pasquinelli, Amy E
- Ruvkun, Gary
- Sharp, Phillip A
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- McManus, Michael T
Producer: 20041102
In:
Nature genetics vol. 36
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132.
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Cell-Type-Specific Alternative Splicing Governs Cell Fate in the Developing Cerebral Cortex. [electronic resource] by
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- Chen, Ming Hui
- Wu, Xuebing
- Kodani, Andrew
- Fan, Jean
- Doan, Ryan
- Ozawa, Manabu
- Ma, Jacqueline
- Yoshida, Nobuaki
- Reiter, Jeremy F
- Black, Douglas L
- Kharchenko, Peter V
- Sharp, Phillip A
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133.
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In vivo genome editing using Staphylococcus aureus Cas9. [electronic resource] by
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- Cong, Le
- Yan, Winston X
- Scott, David A
- Gootenberg, Jonathan S
- Kriz, Andrea J
- Zetsche, Bernd
- Shalem, Ophir
- Wu, Xuebing
- Makarova, Kira S
- Koonin, Eugene V
- Sharp, Phillip A
- Zhang, Feng
Producer: 20150414
In:
Nature vol. 520
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134.
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14-3-3sigma controls mitotic translation to facilitate cytokinesis. [electronic resource] by
- Wilker, Erik W
- van Vugt, Marcel A T M
- Artim, Steven A
- Huang, Paul H
- Petersen, Christian P
- Reinhardt, H Christian
- Feng, Yun
- Sharp, Phillip A
- Sonenberg, Nahum
- White, Forest M
- Yaffe, Michael B
Producer: 20070411
In:
Nature vol. 446
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135.
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Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells. [electronic resource] by
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- Scott, David A
- Kriz, Andrea J
- Chiu, Anthony C
- Hsu, Patrick D
- Dadon, Daniel B
- Cheng, Albert W
- Trevino, Alexandro E
- Konermann, Silvana
- Chen, Sidi
- Jaenisch, Rudolf
- Zhang, Feng
- Sharp, Phillip A
Producer: 20141028
In:
Nature biotechnology vol. 32
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136.
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Lentivirus-delivered stable gene silencing by RNAi in primary cells. [electronic resource] by
- Stewart, Sheila A
- Dykxhoorn, Derek M
- Palliser, Deborah
- Mizuno, Hana
- Yu, Evan Y
- An, Dong Sung
- Sabatini, David M
- Chen, Irvin S Y
- Hahn, William C
- Sharp, Phillip A
- Weinberg, Robert A
- Novina, Carl D
Producer: 20030506
In:
RNA (New York, N.Y.) vol. 9
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137.
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Histone H3K27ac separates active from poised enhancers and predicts developmental state. [electronic resource] by
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- Cheng, Albert W
- Welstead, G Grant
- Kooistra, Tristan
- Carey, Bryce W
- Steine, Eveline J
- Hanna, Jacob
- Lodato, Michael A
- Frampton, Garrett M
- Sharp, Phillip A
- Boyer, Laurie A
- Young, Richard A
- Jaenisch, Rudolf
Producer: 20110512
In:
Proceedings of the National Academy of Sciences of the United States of America vol. 107
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138.
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Simplified silvestrol analogues with potent cytotoxic activity. [electronic resource] by
- Hawkins, Bill C
- Lindqvist, Lisa M
- Nhu, Duong
- Sharp, Phillip P
- Segal, David
- Powell, Andrew K
- Campbell, Michael
- Ryan, Eileen
- Chambers, Jennifer M
- White, Jonathan M
- Rizzacasa, Mark A
- Lessene, Guillaume
- Huang, David C S
- Burns, Christopher J
Producer: 20160310
In:
ChemMedChem vol. 9
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139.
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AAV-mediated direct in vivo CRISPR screen identifies functional suppressors in glioblastoma. [electronic resource] by
- Chow, Ryan D
- Guzman, Christopher D
- Wang, Guangchuan
- Schmidt, Florian
- Youngblood, Mark W
- Ye, Lupeng
- Errami, Youssef
- Dong, Matthew B
- Martinez, Michael A
- Zhang, Sensen
- Renauer, Paul
- Bilguvar, Kaya
- Gunel, Murat
- Sharp, Phillip A
- Zhang, Feng
- Platt, Randall J
- Chen, Sidi
Producer: 20171006
In:
Nature neuroscience vol. 20
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140.
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Coordinated Splicing of Regulatory Detained Introns within Oncogenic Transcripts Creates an Exploitable Vulnerability in Malignant Glioma. [electronic resource] by
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- Stanciu, Monica
- Boutz, Paul L
- Patterson, Jesse C
- Calligaris, David
- Higuchi, Fumi
- Neupane, Rachit
- Fenoglio, Silvia
- Cahill, Daniel P
- Wakimoto, Hiroaki
- Agar, Nathalie Y R
- Yaffe, Michael B
- Sharp, Phillip A
- Hemann, Michael T
- Lees, Jacqueline A
Producer: 20171031
In:
Cancer cell vol. 32
Availability: No items available.
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