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RNA toxicity from the ALS/FTD C9ORF72 expansion is mitigated by antisense intervention. [electronic resource] by
- Donnelly, Christopher J
- Zhang, Ping-Wu
- Pham, Jacqueline T
- Haeusler, Aaron R
- Heusler, Aaron R
- Mistry, Nipun A
- Vidensky, Svetlana
- Daley, Elizabeth L
- Poth, Erin M
- Hoover, Benjamin
- Fines, Daniel M
- Maragakis, Nicholas
- Tienari, Pentti J
- Petrucelli, Leonard
- Traynor, Bryan J
- Wang, Jiou
- Rigo, Frank
- Bennett, C Frank
- Blackshaw, Seth
- Sattler, Rita
- Rothstein, Jeffrey D
Producer: 20140109
In:
Neuron vol. 80
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1122.
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An Isochemogenic Set of Inhibitors To Define the Therapeutic Potential of Histone Deacetylases in β-Cell Protection. [electronic resource] by
- Wagner, Florence F
- Lundh, Morten
- Kaya, Taner
- McCarren, Patrick
- Zhang, Yan-Ling
- Chattopadhyay, Shrikanta
- Gale, Jennifer P
- Galbo, Thomas
- Fisher, Stewart L
- Meier, Bennett C
- Vetere, Amedeo
- Richardson, Sarah
- Morgan, Noel G
- Christensen, Dan Ploug
- Gilbert, Tamara J
- Hooker, Jacob M
- Leroy, Mélanie
- Walpita, Deepika
- Mandrup-Poulsen, Thomas
- Wagner, Bridget K
- Holson, Edward B
Producer: 20161026
In:
ACS chemical biology vol. 11
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Antisense oligonucleotides extend survival and reverse decrement in muscle response in ALS models. [electronic resource] by
- McCampbell, Alex
- Cole, Tracy
- Wegener, Amy J
- Tomassy, Giulio S
- Setnicka, Amy
- Farley, Brandon J
- Schoch, Kathleen M
- Hoye, Mariah L
- Shabsovich, Mark
- Sun, Linhong
- Luo, Yi
- Zhang, Mingdi
- Comfort, Nicole
- Wang, Bin
- Amacker, Jessica
- Thankamony, Sai
- Salzman, David W
- Cudkowicz, Merit
- Graham, Danielle L
- Bennett, C Frank
- Kordasiewicz, Holly B
- Swayze, Eric E
- Miller, Timothy M
Producer: 20190910
In:
The Journal of clinical investigation vol. 128
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1124.
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Genotype-phenotype correlation in Costello syndrome: HRAS mutation analysis in 43 cases. [electronic resource] by
- Kerr, B
- Delrue, M-A
- Sigaudy, S
- Perveen, R
- Marche, M
- Burgelin, I
- Stef, M
- Tang, B
- Eden, O B
- O'Sullivan, J
- De Sandre-Giovannoli, A
- Reardon, W
- Brewer, C
- Bennett, C
- Quarell, O
- M'Cann, E
- Donnai, D
- Stewart, F
- Hennekam, R
- Cavé, H
- Verloes, A
- Philip, N
- Lacombe, D
- Levy, N
- Arveiler, B
- Black, G
Producer: 20060717
In:
Journal of medical genetics vol. 43
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1125.
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Conjugation of hydrophobic moieties enhances potency of antisense oligonucleotides in the muscle of rodents and non-human primates. [electronic resource] by
- Østergaard, Michael E
- Jackson, Michaela
- Low, Audrey
- E Chappell, Alfred
- G Lee, Richard
- Peralta, Rachel Q
- Yu, Jinghua
- Kinberger, Garth A
- Dan, Amy
- Carty, Rick
- Tanowitz, Michael
- Anderson, Patrick
- Kim, Tae-Won
- Fradkin, Linda
- Mullick, Adam E
- Murray, Sue
- Rigo, Frank
- Prakash, Thazha P
- Bennett, C Frank
- Swayze, Eric E
- Gaus, Hans J
- Seth, Punit P
Producer: 20200225
In:
Nucleic acids research vol. 47
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1126.
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Nusinersen versus Sham Control in Later-Onset Spinal Muscular Atrophy. [electronic resource] by
- Mercuri, Eugenio
- Darras, Basil T
- Chiriboga, Claudia A
- Day, John W
- Campbell, Craig
- Connolly, Anne M
- Iannaccone, Susan T
- Kirschner, Janbernd
- Kuntz, Nancy L
- Saito, Kayoko
- Shieh, Perry B
- Tulinius, Már
- Mazzone, Elena S
- Montes, Jacqueline
- Bishop, Kathie M
- Yang, Qingqing
- Foster, Richard
- Gheuens, Sarah
- Bennett, C Frank
- Farwell, Wildon
- Schneider, Eugene
- De Vivo, Darryl C
- Finkel, Richard S
Producer: 20180220
In:
The New England journal of medicine vol. 378
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1127.
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Age-dependent SMN expression in disease-relevant tissue and implications for SMA treatment. [electronic resource] by
- Ramos, Daniel M
- d'Ydewalle, Constantin
- Gabbeta, Vijayalakshmi
- Dakka, Amal
- Klein, Stephanie K
- Norris, Daniel A
- Matson, John
- Taylor, Shannon J
- Zaworski, Phillip G
- Prior, Thomas W
- Snyder, Pamela J
- Valdivia, David
- Hatem, Christine L
- Waters, Ian
- Gupte, Nikhil
- Swoboda, Kathryn J
- Rigo, Frank
- Bennett, C Frank
- Naryshkin, Nikolai
- Paushkin, Sergey
- Crawford, Thomas O
- Sumner, Charlotte J
Producer: 20200608
In:
The Journal of clinical investigation vol. 129
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1128.
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Targeting Huntingtin Expression in Patients with Huntington's Disease. [electronic resource] by
- Tabrizi, Sarah J
- Leavitt, Blair R
- Landwehrmeyer, G Bernhard
- Wild, Edward J
- Saft, Carsten
- Barker, Roger A
- Blair, Nick F
- Craufurd, David
- Priller, Josef
- Rickards, Hugh
- Rosser, Anne
- Kordasiewicz, Holly B
- Czech, Christian
- Swayze, Eric E
- Norris, Daniel A
- Baumann, Tiffany
- Gerlach, Irene
- Schobel, Scott A
- Paz, Erika
- Smith, Anne V
- Bennett, C Frank
- Lane, Roger M
Producer: 20190701
In:
The New England journal of medicine vol. 380
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1129.
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Neurocalcin Delta Suppression Protects against Spinal Muscular Atrophy in Humans and across Species by Restoring Impaired Endocytosis. [electronic resource] by
- Riessland, Markus
- Kaczmarek, Anna
- Schneider, Svenja
- Swoboda, Kathryn J
- Löhr, Heiko
- Bradler, Cathleen
- Grysko, Vanessa
- Dimitriadi, Maria
- Hosseinibarkooie, Seyyedmohsen
- Torres-Benito, Laura
- Peters, Miriam
- Upadhyay, Aaradhita
- Biglari, Nasim
- Kröber, Sandra
- Hölker, Irmgard
- Garbes, Lutz
- Gilissen, Christian
- Hoischen, Alexander
- Nürnberg, Gudrun
- Nürnberg, Peter
- Walter, Michael
- Rigo, Frank
- Bennett, C Frank
- Kye, Min Jeong
- Hart, Anne C
- Hammerschmidt, Matthias
- Kloppenburg, Peter
- Wirth, Brunhilde
Producer: 20170504
In:
American journal of human genetics vol. 100
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1130.
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Deletion or Inhibition of the Oxygen Sensor PHD1 Protects against Ischemic Stroke via Reprogramming of Neuronal Metabolism. [electronic resource] by
- Quaegebeur, Annelies
- Segura, Inmaculada
- Schmieder, Roberta
- Verdegem, Dries
- Decimo, Ilaria
- Bifari, Francesco
- Dresselaers, Tom
- Eelen, Guy
- Ghosh, Debapriva
- Davidson, Shawn M
- Schoors, Sandra
- Broekaert, Dorien
- Cruys, Bert
- Govaerts, Kristof
- De Legher, Carla
- Bouché, Ann
- Schoonjans, Luc
- Ramer, Matt S
- Hung, Gene
- Bossaert, Goele
- Cleveland, Don W
- Himmelreich, Uwe
- Voets, Thomas
- Lemmens, Robin
- Bennett, C Frank
- Robberecht, Wim
- De Bock, Katrien
- Dewerchin, Mieke
- Ghesquière, Bart
- Fendt, Sarah-Maria
- Carmeliet, Peter
Producer: 20161031
In:
Cell metabolism vol. 23
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1131.
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Positive reinforcement targeting abstinence in substance misuse (PRAISe): Study protocol for a Cluster RCT & process evaluation of contingency management. [electronic resource] by
- Metrebian, N
- Weaver, T
- Pilling, S
- Hellier, J
- Byford, S
- Shearer, J
- Mitcheson, L
- Astbury, M
- Bijral, P
- Bogdan, N
- Bowden-Jones, O
- Day, E
- Dunn, J
- Finch, E
- Forshall, S
- Glasper, A
- Morse, G
- Akhtar, S
- Bajaria, J
- Bennett, C
- Bishop, E
- Charles, V
- Davey, C
- Desai, R
- Goodfellow, C
- Haque, F
- Little, N
- McKechnie, H
- Morris, J
- Mosler, F
- Mutz, J
- Pauli, R
- Poovendran, D
- Slater, E
- Strang, J
Producer: 20191016
In:
Contemporary clinical trials vol. 71
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1132.
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Structure-activity relationship of heterobase-modified 2'-C-methyl ribonucleosides as inhibitors of hepatitis C virus RNA replication. [electronic resource] by
- Eldrup, Anne B
- Prhavc, Marija
- Brooks, Jennifer
- Bhat, Balkrishen
- Prakash, Thazha P
- Song, Quanlai
- Bera, Sanjib
- Bhat, Neelima
- Dande, Prasad
- Cook, P Dan
- Bennett, C Frank
- Carroll, Steven S
- Ball, Richard G
- Bosserman, Michele
- Burlein, Christine
- Colwell, Lawrence F
- Fay, John F
- Flores, Osvaldo A
- Getty, Krista
- LaFemina, Robert L
- Leone, Joseph
- MacCoss, Malcolm
- McMasters, Daniel R
- Tomassini, Joanne E
- Von Langen, Derek
- Wolanski, Bohdan
- Olsen, David B
Producer: 20041110
In:
Journal of medicinal chemistry vol. 47
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1133.
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Protein-RNA Networks Regulated by Normal and ALS-Associated Mutant HNRNPA2B1 in the Nervous System. [electronic resource] by
- Martinez, Fernando J
- Pratt, Gabriel A
- Van Nostrand, Eric L
- Batra, Ranjan
- Huelga, Stephanie C
- Kapeli, Katannya
- Freese, Peter
- Chun, Seung J
- Ling, Karen
- Gelboin-Burkhart, Chelsea
- Fijany, Layla
- Wang, Harrison C
- Nussbacher, Julia K
- Broski, Sara M
- Kim, Hong Joo
- Lardelli, Rea
- Sundararaman, Balaji
- Donohue, John P
- Javaherian, Ashkan
- Lykke-Andersen, Jens
- Finkbeiner, Steven
- Bennett, C Frank
- Ares, Manuel
- Burge, Christopher B
- Taylor, J Paul
- Rigo, Frank
- Yeo, Gene W
Producer: 20170726
In:
Neuron vol. 92
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1134.
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Targeted degradation of sense and antisense C9orf72 RNA foci as therapy for ALS and frontotemporal degeneration. [electronic resource] by
- Lagier-Tourenne, Clotilde
- Baughn, Michael
- Rigo, Frank
- Sun, Shuying
- Liu, Patrick
- Li, Hai-Ri
- Jiang, Jie
- Watt, Andrew T
- Chun, Seung
- Katz, Melanie
- Qiu, Jinsong
- Sun, Ying
- Ling, Shuo-Chien
- Zhu, Qiang
- Polymenidou, Magdalini
- Drenner, Kevin
- Artates, Jonathan W
- McAlonis-Downes, Melissa
- Markmiller, Sebastian
- Hutt, Kasey R
- Pizzo, Donald P
- Cady, Janet
- Harms, Matthew B
- Baloh, Robert H
- Vandenberg, Scott R
- Yeo, Gene W
- Fu, Xiang-Dong
- Bennett, C Frank
- Cleveland, Don W
- Ravits, John
Producer: 20140122
In:
Proceedings of the National Academy of Sciences of the United States of America vol. 110
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1135.
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Recombinant HIV-1 vaccine candidates based on replication-defective flavivirus vector. [electronic resource] by
- Giel-Moloney, M
- Esteban, M
- Oakes, B H
- Vaine, M
- Asbach, B
- Wagner, R
- Mize, G J
- Spies, A G
- McElrath, J
- Perreau, M
- Roger, T
- Ives, A
- Calandra, T
- Weiss, D
- Perdiguero, B
- Kibler, K V
- Jacobs, B
- Ding, S
- Tomaras, G D
- Montefiori, D C
- Ferrari, G
- Yates, N L
- Roederer, M
- Kao, S F
- Foulds, K E
- Mayer, B T
- Bennett, C
- Gottardo, R
- Parrington, M
- Tartaglia, J
- Phogat, S
- Pantaleo, G
- Kleanthous, H
- Pugachev, K V
Producer: 20201207
In:
Scientific reports vol. 9
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1136.
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Sub-Kelvin cooling for two kilopixel bolometer arrays in the PIPER receiver. [electronic resource] by
- Switzer, E R
- Ade, P A R
- Baildon, T
- Benford, D
- Bennett, C L
- Chuss, D T
- Datta, R
- Eimer, J R
- Fixsen, D J
- Gandilo, N N
- Essinger-Hileman, T M
- Halpern, M
- Hilton, G
- Irwin, K
- Jhabvala, C
- Kimball, M
- Kogut, A
- Lazear, J
- Lowe, L N
- McMahon, J J
- Miller, T M
- Mirel, P
- Moseley, S H
- Pawlyk, S
- Rodriguez, S
- Sharp, E
- Shirron, P
- Staguhn, J G
- Sullivan, D F
- Taraschi, P
- Tucker, C E
- Walts, A
- Wollack, E J
Producer: 20191004
In:
The Review of scientific instruments vol. 90
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1137.
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The unexpected surface of asteroid (101955) Bennu. [electronic resource] by
- Lauretta, D S
- DellaGiustina, D N
- Bennett, C A
- Golish, D R
- Becker, K J
- Balram-Knutson, S S
- Barnouin, O S
- Becker, T L
- Bottke, W F
- Boynton, W V
- Campins, H
- Clark, B E
- Connolly, H C
- Drouet d'Aubigny, C Y
- Dworkin, J P
- Emery, J P
- Enos, H L
- Hamilton, V E
- Hergenrother, C W
- Howell, E S
- Izawa, M R M
- Kaplan, H H
- Nolan, M C
- Rizk, B
- Roper, H L
- Scheeres, D J
- Smith, P H
- Walsh, K J
- Wolner, C W V
Producer: 20190819
In:
Nature vol. 568
Availability: No items available.
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1138.
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Gain of Toxicity from ALS/FTD-Linked Repeat Expansions in C9ORF72 Is Alleviated by Antisense Oligonucleotides Targeting GGGGCC-Containing RNAs. [electronic resource] by
- Jiang, Jie
- Zhu, Qiang
- Gendron, Tania F
- Saberi, Shahram
- McAlonis-Downes, Melissa
- Seelman, Amanda
- Stauffer, Jennifer E
- Jafar-Nejad, Paymaan
- Drenner, Kevin
- Schulte, Derek
- Chun, Seung
- Sun, Shuying
- Ling, Shuo-Chien
- Myers, Brian
- Engelhardt, Jeffery
- Katz, Melanie
- Baughn, Michael
- Platoshyn, Oleksandr
- Marsala, Martin
- Watt, Andy
- Heyser, Charles J
- Ard, M Colin
- De Muynck, Louis
- Daughrity, Lillian M
- Swing, Deborah A
- Tessarollo, Lino
- Jung, Chris J
- Delpoux, Arnaud
- Utzschneider, Daniel T
- Hedrick, Stephen M
- de Jong, Pieter J
- Edbauer, Dieter
- Van Damme, Philip
- Petrucelli, Leonard
- Shaw, Christopher E
- Bennett, C Frank
- Da Cruz, Sandrine
- Ravits, John
- Rigo, Frank
- Cleveland, Don W
- Lagier-Tourenne, Clotilde
Producer: 20170822
In:
Neuron vol. 90
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1139.
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Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 8. Pharmacological optimization of orally bioavailable 2-pyridone-containing peptidomimetics. [electronic resource] by
- Dragovich, Peter S
- Prins, Thomas J
- Zhou, Ru
- Johnson, Theodore O
- Hua, Ye
- Luu, Hiep T
- Sakata, Sylvie K
- Brown, Edward L
- Maldonado, Fausto C
- Tuntland, Tove
- Lee, Caroline A
- Fuhrman, Shella A
- Zalman, Leora S
- Patick, Amy K
- Matthews, David A
- Wu, Ellen Y
- Guo, Ming
- Borer, Bennett C
- Nayyar, Naresh K
- Moran, Terence
- Chen, Lijian
- Rejto, Paul A
- Rose, Peter W
- Guzman, Mark C
- Dovalsantos, Elena Z
- Lee, Steven
- McGee, Kevin
- Mohajeri, Michael
- Liese, Andreas
- Tao, Junhua
- Kosa, Maha B
- Liu, Bo
- Batugo, Minerva R
- Gleeson, Jean-Paul R
- Wu, Zhen Ping
- Liu, Jia
- Meador, James W
- Ferre, Rose Ann
Producer: 20031112
In:
Journal of medicinal chemistry vol. 46
Availability: No items available.
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1140.
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Shape of (101955) Bennu indicative of a rubble pile with internal stiffness. [electronic resource] by
- Barnouin, O S
- Daly, M G
- Palmer, E E
- Gaskell, R W
- Weirich, J R
- Johnson, C L
- Asad, M M Al
- Roberts, J H
- Perry, M E
- Susorney, H C M
- Daly, R T
- Bierhaus, E B
- Seabrook, J A
- Espiritu, R C
- Nair, A H
- Nguyen, L
- Neumann, G A
- Ernst, C M
- Boynton, W V
- Nolan, M C
- Adam, C D
- Moreau, M C
- Risk, B
- D'Aubigny, C Drouet
- Jawin, E R
- Walsh, K J
- Michel, P
- Schwartz, S R
- Ballouz, R-L
- Mazarico, E M
- Scheeres, D J
- McMahon, J
- Bottke, W
- Sugita, S
- Hirata, N
- Hirata, N
- Watanabe, S
- Burke, K N
- DellaGuistina, D N
- Bennett, C A
- Lauretta, D S
Publication details: Nature geoscience Apr 2019
In:
Nature geoscience vol. 12
Availability: No items available.
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