Results
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101.
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102.
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103.
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Dihydrofolate reductase: x-ray structure of the binary complex with methotrexate. [electronic resource] by
- Matthews, D A
- Alden, R A
- Bolin, J T
- Freer, S T
- Hamlin, R
- Xuong, N
- Kraut, J
- Poe, M
- Williams, M
- Hoogsteen, K
Producer: 19770902
In:
Science (New York, N.Y.) vol. 197
Availability: No items available.
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104.
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Structure of the human cytomegalovirus protease catalytic domain reveals a novel serine protease fold and catalytic triad. [electronic resource] by
- Chen, P
- Tsuge, H
- Almassy, R J
- Gribskov, C L
- Katoh, S
- Vanderpool, D L
- Margosiak, S A
- Pinko, C
- Matthews, D A
- Kan, C C
Producer: 19961016
In:
Cell vol. 86
Availability: No items available.
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105.
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Genomic mapping and evolution of human GABA(A) receptor subunit gene clusters. [electronic resource] by
- Bailey, M E
- Matthews, D A
- Riley, B P
- Albrecht, B E
- Kostrzewa, M
- Hicks, A A
- Harris, R
- Müller, U
- Darlison, M G
- Johnson, K J
Producer: 19990902
In:
Mammalian genome : official journal of the International Mammalian Genome Society vol. 10
Availability: No items available.
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106.
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Structure of human rhinovirus 3C protease reveals a trypsin-like polypeptide fold, RNA-binding site, and means for cleaving precursor polyprotein. [electronic resource] by
- Matthews, D A
- Smith, W W
- Ferre, R A
- Condon, B
- Budahazi, G
- Sisson, W
- Villafranca, J E
- Janson, C A
- McElroy, H E
- Gribskov, C L
Producer: 19940711
In:
Cell vol. 77
Availability: No items available.
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107.
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Design of thymidylate synthase inhibitors using protein crystal structures: the synthesis and biological evaluation of a novel class of 5-substituted quinazolinones. [electronic resource] by
- Webber, S E
- Bleckman, T M
- Attard, J
- Deal, J G
- Kathardekar, V
- Welsh, K M
- Webber, S
- Janson, C A
- Matthews, D A
- Smith, W W
Producer: 19930428
In:
Journal of medicinal chemistry vol. 36
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108.
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Design and synthesis of novel 6,7-imidazotetrahydroquinoline inhibitors of thymidylate synthase using iterative protein crystal structure analysis. [electronic resource] by
- Reich, S H
- Fuhry, M A
- Nguyen, D
- Pino, M J
- Welsh, K M
- Webber, S
- Janson, C A
- Jordan, S R
- Matthews, D A
- Smith, W W
Producer: 19920417
In:
Journal of medicinal chemistry vol. 35
Availability: No items available.
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109.
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Refined crystal structures of Escherichia coli and chicken liver dihydrofolate reductase containing bound trimethoprim. [electronic resource] by
- Matthews, D A
- Bolin, J T
- Burridge, J M
- Filman, D J
- Volz, K W
- Kaufman, B T
- Beddell, C R
- Champness, J N
- Stammers, D K
- Kraut, J
Producer: 19850215
In:
The Journal of biological chemistry vol. 260
Availability: No items available.
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110.
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Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 3. Structure-activity studies of ketomethylene-containing peptidomimetics. [electronic resource] by
- Dragovich, P S
- Prins, T J
- Zhou, R
- Fuhrman, S A
- Patick, A K
- Matthews, D A
- Ford, C E
- Meador, J W
- Ferre, R A
- Worland, S T
Producer: 19990520
In:
Journal of medicinal chemistry vol. 42
Availability: No items available.
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111.
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Dihydrofolate reductase from Lactobacillus casei. X-ray structure of the enzyme methotrexate.NADPH complex. [electronic resource] by
- Matthews, D A
- Alden, R A
- Bolin, J T
- Filman, D J
- Freer, S T
- Hamlin, R
- Hol, W G
- Kisliuk, R L
- Pastore, E J
- Plante, L T
- Xuong, N
- Kraut, J
Producer: 19781129
In:
The Journal of biological chemistry vol. 253
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112.
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Identification of mutations contributing to the reduced virulence of a modified strain of respiratory syncytial virus. [electronic resource] by
- Tolley, K P
- Marriott, A C
- Simpson, A
- Plows, D J
- Matthews, D A
- Longhurst, S J
- Evans, J E
- Johnson, J L
- Cane, P A
- Randolph, V B
- Easton, A J
- Pringle, C R
Producer: 19970509
In:
Vaccine vol. 14
Availability: No items available.
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113.
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Design, synthesis, and evaluation of nonpeptidic inhibitors of human rhinovirus 3C protease. [electronic resource] by
- Webber, S E
- Tikhe, J
- Worland, S T
- Fuhrman, S A
- Hendrickson, T F
- Matthews, D A
- Love, R A
- Patick, A K
- Meador, J W
- Ferre, R A
- Brown, E L
- DeLisle, D M
- Ford, C E
- Binford, S L
Producer: 19970124
In:
Journal of medicinal chemistry vol. 39
Availability: No items available.
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114.
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In vitro antiviral activity of AG7088, a potent inhibitor of human rhinovirus 3C protease. [electronic resource] by
- Patick, A K
- Binford, S L
- Brothers, M A
- Jackson, R L
- Ford, C E
- Diem, M D
- Maldonado, F
- Dragovich, P S
- Zhou, R
- Prins, T J
- Fuhrman, S A
- Meador, J W
- Zalman, L S
- Matthews, D A
- Worland, S T
Producer: 19991213
In:
Antimicrobial agents and chemotherapy vol. 43
Availability: No items available.
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115.
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Structure-based design of irreversible, tripeptidyl human rhinovirus 3C protease inhibitors containing N-methyl amino acids. [electronic resource] by
- Dragovich, P S
- Webber, S E
- Prins, T J
- Zhou, R
- Marakovits, J T
- Tikhe, J G
- Fuhrman, S A
- Patick, A K
- Matthews, D A
- Ford, C E
- Brown, E L
- Binford, S L
- Meador, J W
- Ferre, R A
- Worland, S T
Producer: 19991124
In:
Bioorganic & medicinal chemistry letters vol. 9
Availability: No items available.
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116.
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Substituted benzamide inhibitors of human rhinovirus 3C protease: structure-based design, synthesis, and biological evaluation. [electronic resource] by
- Reich, S H
- Johnson, T
- Wallace, M B
- Kephart, S E
- Fuhrman, S A
- Worland, S T
- Matthews, D A
- Hendrickson, T F
- Chan, F
- Meador, J
- Ferre, R A
- Brown, E L
- DeLisle, D M
- Patick, A K
- Binford, S L
- Ford, C E
Producer: 20000629
In:
Journal of medicinal chemistry vol. 43
Availability: No items available.
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117.
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Tripeptide aldehyde inhibitors of human rhinovirus 3C protease: design, synthesis, biological evaluation, and cocrystal structure solution of P1 glutamine isosteric replacements. [electronic resource] by
- Webber, S E
- Okano, K
- Little, T L
- Reich, S H
- Xin, Y
- Fuhrman, S A
- Matthews, D A
- Love, R A
- Hendrickson, T F
- Patick, A K
- Meador, J W
- Ferre, R A
- Brown, E L
- Ford, C E
- Binford, S L
- Worland, S T
Producer: 19980803
In:
Journal of medicinal chemistry vol. 41
Availability: No items available.
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118.
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Design and synthesis of irreversible depsipeptidyl human rhinovirus 3C protease inhibitors. [electronic resource] by
- Webber, S E
- Marakovits, J T
- Dragovich, P S
- Prins, T J
- Zhou, R
- Fuhrman, S A
- Patick, A K
- Matthews, D A
- Lee, C A
- Srinivasan, B
- Moran, T
- Ford, C E
- Brothers, M A
- Harr, J E
- Meador, J W
- Ferre, R A
- Worland, S T
Producer: 20011210
In:
Bioorganic & medicinal chemistry letters vol. 11
Availability: No items available.
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119.
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Structure-based design of ketone-containing, tripeptidyl human rhinovirus 3C protease inhibitors. [electronic resource] by
- Dragovich, P S
- Zhou, R
- Webber, S E
- Prins, T J
- Kwok, A K
- Okano, K
- Fuhrman, S A
- Zalman, L S
- Maldonado, F C
- Brown, E L
- Meador, J W
- Patick, A K
- Ford, C E
- Brothers, M A
- Binford, S L
- Matthews, D A
- Ferre, R A
- Worland, S T
Producer: 20000228
In:
Bioorganic & medicinal chemistry letters vol. 10
Availability: No items available.
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120.
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Structure-assisted design of mechanism-based irreversible inhibitors of human rhinovirus 3C protease with potent antiviral activity against multiple rhinovirus serotypes. [electronic resource] by
- Matthews, D A
- Dragovich, P S
- Webber, S E
- Fuhrman, S A
- Patick, A K
- Zalman, L S
- Hendrickson, T F
- Love, R A
- Prins, T J
- Marakovits, J T
- Zhou, R
- Tikhe, J
- Ford, C E
- Meador, J W
- Ferre, R A
- Brown, E L
- Binford, S L
- Brothers, M A
- DeLisle, D M
- Worland, S T
Producer: 19991021
In:
Proceedings of the National Academy of Sciences of the United States of America vol. 96
Availability: No items available.
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