Results
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101.
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N-heteroaryl-2-phenyl-3-(benzyloxy)piperidines: a novel class of potent orally active human NK1 antagonists. [electronic resource] by
- Ladduwahetty, T
- Baker, R
- Cascieri, M A
- Chambers, M S
- Haworth, K
- Keown, L E
- MacIntyre, D E
- Metzger, J M
- Owen, S
- Rycroft, W
- Sadowski, S
- Seward, E M
- Shepheard, S L
- Swain, C J
- Tattersall, F D
- Watt, A P
- Williamson, D W
- Hargreaves, R J
Producer: 19960906
In:
Journal of medicinal chemistry vol. 39
Availability: No items available.
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102.
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Discovery of a potent, orally bioavailable beta(3) adrenergic receptor agonist, (R)-N-[4-[2-[[2-hydroxy-2-(3-pyridinyl)ethyl]amino]ethyl]phenyl]-4-[4 -[4-(trifluoromethyl)phenyl]thiazol-2-yl]benzenesulfonamide. [electronic resource] by
- Mathvink, R J
- Tolman, J S
- Chitty, D
- Candelore, M R
- Cascieri, M A
- Colwell, L F
- Deng, L
- Feeney, W P
- Forrest, M J
- Hom, G J
- MacIntyre, D E
- Miller, R R
- Stearns, R A
- Tota, L
- Wyvratt, M J
- Fisher, M H
- Weber, A E
Producer: 20001116
In:
Journal of medicinal chemistry vol. 43
Availability: No items available.
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103.
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Discovery of an orally bioavailable alkyl oxadiazole beta3 adrenergic receptor agonist. [electronic resource] by
- Feng, D D
- Biftu, T
- Candelore, M R
- Cascieri, M A
- Colwell, L F
- Deng, L
- Feeney, W P
- Forrest, M J
- Hom, G J
- MacIntyre, D E
- Miller, R R
- Stearns, R A
- Strader, C D
- Tota, L
- Wyvratt, M J
- Fisher, M H
- Weber, A E
Producer: 20001107
In:
Bioorganic & medicinal chemistry letters vol. 10
Availability: No items available.
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104.
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L-770,644: a potent and selective human beta3 adrenergic receptor agonist with improved oral bioavailability. [electronic resource] by
- Shih, T L
- Candelore, M R
- Cascieri, M A
- Chiu, S H
- Colwell, L F
- Deng, L
- Feeney, W P
- Forrest, M J
- Hom, G J
- MacIntyre, D E
- Miller, R R
- Stearns, R A
- Strader, C D
- Tota, L
- Wyvratt, M J
- Fisher, M H
- Weber, A E
Producer: 19990819
In:
Bioorganic & medicinal chemistry letters vol. 9
Availability: No items available.
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105.
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Role of the melanocortin-4 receptor in metabolic rate and food intake in mice. [electronic resource] by
- Chen, A S
- Metzger, J M
- Trumbauer, M E
- Guan, X M
- Yu, H
- Frazier, E G
- Marsh, D J
- Forrest, M J
- Gopal-Truter, S
- Fisher, J
- Camacho, R E
- Strack, A M
- Mellin, T N
- MacIntyre, D E
- Chen, H Y
- Van der Ploeg, L H
Producer: 20010125
In:
Transgenic research vol. 9
Availability: No items available.
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106.
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Synthesis and SAR of benzyl and phenoxymethylene oxadiazole benzenesulfonamides as selective beta3 adrenergic receptor agonist antiobesity agents. [electronic resource] by
- Biftu, T
- Feng, D D
- Liang, G B
- Kuo, H
- Qian, X
- Naylor, E M
- Colandrea, V J
- Candelore, M R
- Cascieri, M A
- Colwell, L F
- Forrest, M J
- Hom, G J
- MacIntyre, D E
- Stearns, R A
- Strader, C D
- Wyvratt, M J
- Fisher, M H
- Weber, A E
Producer: 20001107
In:
Bioorganic & medicinal chemistry letters vol. 10
Availability: No items available.
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107.
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Human beta3 adrenergic receptor agonists containing imidazolidinone and imidazolone benzenesulfonamides. [electronic resource] by
- Naylor, E M
- Parmee, E R
- Colandrea, V J
- Perkins, L
- Brockunier, L
- Candelore, M R
- Cascieri, M A
- Colwell, L F
- Deng, L
- Feeney, W P
- Forrest, M J
- Hom, G J
- MacIntyre, D E
- Strader, C D
- Tota, L
- Wang, P R
- Wyvratt, M J
- Fisher, M H
- Weber, A E
Producer: 19990604
In:
Bioorganic & medicinal chemistry letters vol. 9
Availability: No items available.
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108.
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Human beta3 adrenergic receptor agonists containing cyclic ureidobenzenesulfonamides. [electronic resource] by
- Parmee, E R
- Naylor, E M
- Perkins, L
- Colandrea, V J
- Ok, H O
- Candelore, M R
- Cascieri, M A
- Deng, L
- Feeney, W P
- Forrest, M J
- Hom, G J
- MacIntyre, D E
- Miller, R R
- Stearns, R A
- Strader, C D
- Tota, L
- Wyvratt, M J
- Fisher, M H
- Weber, A E
Producer: 19990604
In:
Bioorganic & medicinal chemistry letters vol. 9
Availability: No items available.
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109.
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Inactivation of the mouse melanocortin-3 receptor results in increased fat mass and reduced lean body mass. [electronic resource] by
- Chen, A S
- Marsh, D J
- Trumbauer, M E
- Frazier, E G
- Guan, X M
- Yu, H
- Rosenblum, C I
- Vongs, A
- Feng, Y
- Cao, L
- Metzger, J M
- Strack, A M
- Camacho, R E
- Mellin, T N
- Nunes, C N
- Min, W
- Fisher, J
- Gopal-Truter, S
- MacIntyre, D E
- Chen, H Y
- Van der Ploeg, L H
Producer: 20001030
In:
Nature genetics vol. 26
Availability: No items available.
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110.
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Phosphorylated morpholine acetal human neurokinin-1 receptor antagonists as water-soluble prodrugs. [electronic resource] by
- Hale, J J
- Mills, S G
- MacCoss, M
- Dorn, C P
- Finke, P E
- Budhu, R J
- Reamer, R A
- Huskey, S E
- Luffer-Atlas, D
- Dean, B J
- McGowan, E M
- Feeney, W P
- Chiu, S H
- Cascieri, M A
- Chicchi, G G
- Kurtz, M M
- Sadowski, S
- Ber, E
- Tattersall, F D
- Rupniak, N M
- Williams, A R
- Rycroft, W
- Hargreaves, R
- Metzger, J M
- MacIntyre, D E
Producer: 20000413
In:
Journal of medicinal chemistry vol. 43
Availability: No items available.
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111.
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3-Pyridyloxypropanolamine agonists of the beta 3 adrenergic receptor with improved pharmacokinetic properties. [electronic resource] by
- Weber, A E
- Ok, H O
- Alvaro, R F
- Candelore, M R
- Cascieri, M A
- Chiu, S H
- Deng, L
- Forrest, M J
- Hom, G J
- Hutchins, J E
- Kao, J
- MacIntyre, D E
- Mathvink, R J
- McLoughlin, D
- Miller, R R
- Newbold, R C
- Olah, T V
- Parmee, E R
- Perkins, L
- Stearns, R A
- Strader, C D
- Szumiloski, J
- Tang, Y S
- Tota, L
- Fisher, M H
Producer: 19990128
In:
Bioorganic & medicinal chemistry letters vol. 8
Availability: No items available.
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112.
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A selective human beta3 adrenergic receptor agonist increases metabolic rate in rhesus monkeys. [electronic resource] by
- Fisher, M H
- Amend, A M
- Bach, T J
- Barker, J M
- Brady, E J
- Candelore, M R
- Carroll, D
- Cascieri, M A
- Chiu, S H
- Deng, L
- Forrest, M J
- Hegarty-Friscino, B
- Guan, X M
- Hom, G J
- Hutchins, J E
- Kelly, L J
- Mathvink, R J
- Metzger, J M
- Miller, R R
- Ok, H O
- Parmee, E R
- Saperstein, R
- Strader, C D
- Stearns, R A
- MacIntyre, D E
Producer: 19980626
In:
The Journal of clinical investigation vol. 101
Availability: No items available.
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113.
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A potent, nonpeptidyl 1H-quinolone antagonist for the gonadotropin-releasing hormone receptor. [electronic resource] by
- DeVita, R J
- Walsh, T F
- Young, J R
- Jiang, J
- Ujjainwalla, F
- Toupence, R B
- Parikh, M
- Huang, S X
- Fair, J A
- Goulet, M T
- Wyvratt, M J
- Lo, J L
- Ren, N
- Yudkovitz, J B
- Yang, Y T
- Cheng, K
- Cui, J
- Mount, G
- Rohrer, S P
- Schaeffer, J M
- Rhodes, L
- Drisko, J E
- McGowan, E
- MacIntyre, D E
- Vincent, S
- Carlin, J R
- Cameron, J
- Smith, R G
Producer: 20010503
In:
Journal of medicinal chemistry vol. 44
Availability: No items available.
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