Protease-activated receptor-1 can mediate responses to SFLLRN in thrombin-desensitized cells: evidence for a novel mechanism for preventing or terminating signaling by PAR1's tethered ligand. [electronic resource]
- Biochemistry Feb 1999
- 2486-93 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0006-2960
10.1021/bi982527i doi
Amino Acid Sequence Animals Binding Sites--genetics Calcium--metabolism Cell Line Fibroblasts--enzymology Humans Hydrolysis Ligands Lung--cytology Mice Mice, Knockout Molecular Sequence Data Peptide Fragments--pharmacology Receptor, PAR-1 Receptors, Thrombin--biosynthesis Signal Transduction--drug effects Thrombin--agonists Time Factors