TY - GEN AU - You,M AU - Yu,D H AU - Feng,G S TI - Shp-2 tyrosine phosphatase functions as a negative regulator of the interferon-stimulated Jak/STAT pathway SN - 0270-7306 PY - 1999///0325 KW - Animals KW - Caspase 1 KW - metabolism KW - Cell Line KW - DNA-Binding Proteins KW - genetics KW - Enzyme Induction KW - Fibroblasts KW - cytology KW - Humans KW - Interferon-alpha KW - Interferon-gamma KW - Intracellular Signaling Peptides and Proteins KW - Janus Kinase 1 KW - Membrane Proteins KW - Mice KW - Mutagenesis KW - Phenotype KW - Phosphorylation KW - Protein Tyrosine Phosphatase, Non-Receptor Type 11 KW - Protein Tyrosine Phosphatase, Non-Receptor Type 6 KW - Protein Tyrosine Phosphatases KW - Protein-Tyrosine Kinases KW - Receptor, Interferon alpha-beta KW - Receptors, Interferon KW - SH2 Domain-Containing Protein Tyrosine Phosphatases KW - STAT1 Transcription Factor KW - STAT2 Transcription Factor KW - Signal Transduction KW - Trans-Activators KW - Interferon gamma Receptor N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1128/MCB.19.3.2416 ER -