IL-2, but not IL-4 and other cytokines, induces phosphorylation of a 98-kDa protein associated with SHP-2, phosphatidylinositol 3'-kinase, and Grb2. [electronic resource]
- Journal of immunology (Baltimore, Md. : 1950) Feb 1999
- 2081-6 p. digital
Publication Type: Journal Article
0022-1767
Adaptor Proteins, Signal Transducing Antigens, Differentiation Cells, Cultured Cytokines--physiology GRB2 Adaptor Protein Humans Interleukin-2--physiology Interleukin-4--physiology Intracellular Signaling Peptides and Proteins Janus Kinase 3 Killer Cells, Natural--enzymology Macromolecular Substances Membrane Glycoproteins--metabolism Molecular Weight Neural Cell Adhesion Molecule L1 Neural Cell Adhesion Molecules--metabolism Phosphatidylinositol 3-Kinases--metabolism Phosphoproteins--biosynthesis Phosphorylation Protein Tyrosine Phosphatase, Non-Receptor Type 11 Protein Tyrosine Phosphatase, Non-Receptor Type 6 Protein Tyrosine Phosphatases--biosynthesis Protein-Tyrosine Kinases--physiology Proteins--metabolism Receptors, Immunologic SH2 Domain-Containing Protein Tyrosine Phosphatases Signal Transduction--immunology Substrate Specificity--immunology T-Lymphocytes--enzymology src Homology Domains--immunology