TY - GEN AU - Tasara,T AU - Amacker,M AU - Hübscher,U TI - Intramolecular chimeras of the p51 subunit between HIV-1 and FIV reverse transcriptases suggest a stabilizing function for the p66 subunit in the heterodimeric enzyme SN - 0006-2960 PY - 1999///0223 KW - Amino Acid Sequence KW - Animals KW - Cats KW - DNA, Viral KW - biosynthesis KW - Dideoxynucleotides KW - Dimerization KW - Enzyme Activation KW - genetics KW - Enzyme Stability KW - Genetic Vectors KW - chemical synthesis KW - HIV Reverse Transcriptase KW - antagonists & inhibitors KW - Humans KW - Immunodeficiency Virus, Feline KW - enzymology KW - Molecular Sequence Data KW - Nevirapine KW - pharmacology KW - Peptide Fragments KW - Protein Processing, Post-Translational KW - RNA-Directed DNA Polymerase KW - chemistry KW - Recombinant Fusion Proteins KW - Reverse Transcriptase Inhibitors KW - Ribonuclease H KW - Structure-Activity Relationship KW - Thymine Nucleotides KW - Zidovudine KW - analogs & derivatives N1 - Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1021/bi9821162 ER -