Synergistic activation of mitogen-activated protein kinase by cyclic AMP and myeloid growth factors opposes cyclic AMP's growth-inhibitory effects. [electronic resource]
- Blood Jan 1999
- 537-53 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0006-4971
Animals Calcium-Calmodulin-Dependent Protein Kinases--genetics Cell Division--drug effects Cell Line Cyclic AMP--biosynthesis Drug Synergism Enzyme Activation--drug effects Gene Expression Granulocytes Hematopoiesis--drug effects Interleukin-3--pharmacology MAP Kinase Kinase 1 MAP Kinase Kinase 2 Macrophage Colony-Stimulating Factor--pharmacology Mice Mitogen-Activated Protein Kinase 1 Mitogen-Activated Protein Kinase Kinases Protein Serine-Threonine Kinases--metabolism Protein-Tyrosine Kinases--metabolism Proto-Oncogene Proteins c-raf--metabolism Receptor, Macrophage Colony-Stimulating Factor--genetics Transfection