Hulme, C Quaternary substituted PDE IV inhibitors II: the synthesis and in vitro evaluation of a novel series of gamma-lactams. [electronic resource] - Bioorganic & medicinal chemistry letters Feb 1998 - 399-404 p. digital Publication Type: Journal Article ISSN: 0960-894X Standard No.: 10.1016/s0960-894x(98)00036-5 doi Subjects--Topical Terms: 3',5'-Cyclic-AMP Phosphodiesterases--antagonists & inhibitorsCyclic Nucleotide Phosphodiesterases, Type 4Lactams--chemical synthesisPhosphodiesterase Inhibitors--chemical synthesisStructure-Activity Relationship