Gentile, D M

The role of CYP2C in the in vitro bioactivation of the contraceptive steroid desogestrel. [electronic resource] - The Journal of pharmacology and experimental therapeutics Dec 1998 - 975-82 p. digital

Publication Type: Journal Article

0022-3565


Aryl Hydrocarbon Hydroxylases
Biotransformation
Cell Line
Contraceptives, Oral, Synthetic--pharmacology
Cytochrome P-450 CYP2C19
Cytochrome P-450 CYP2C9
Cytochrome P-450 CYP3A
Cytochrome P-450 Enzyme Inhibitors
Cytochrome P-450 Enzyme System--genetics
Desogestrel--metabolism
Enzyme Inhibitors--pharmacology
Humans
Hydroxylation
Microsomes, Liver--enzymology
Mixed Function Oxygenases--metabolism
Progesterone Congeners--pharmacology
Steroid 16-alpha-Hydroxylase
Steroid Hydroxylases--antagonists & inhibitors