Scott, S P <br/><br/>
Three residues predicted by molecular modeling to interact with the purine moiety alter ligand binding and channel gating in cyclic nucleotide-gated channels.  [electronic resource] 

 -  Biochemistry  Dec 1998 
 - 17239-52 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S. 
<br/><br/><label>ISSN: </label>0006-2960 
<br/><br/><label>Standard No.: </label>10.1021/bi981185d  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Amino Acid Substitution--genetics<br/>Amino Acids--metabolism<br/>Animals<br/>Aspartic Acid--genetics<br/>Cattle<br/>Cyclic GMP--genetics<br/>Cyclic Nucleotide-Gated Cation Channels<br/>Evoked Potentials--drug effects<br/>Ion Channels--genetics<br/>Ligands<br/>Lysine--genetics<br/>Models, Molecular<br/>Mutagenesis, Site-Directed<br/>Nickel--pharmacology<br/>Patch-Clamp Techniques<br/>Phenylalanine--genetics<br/>Protein Binding--drug effects<br/>Protons<br/>Purine Nucleotides--metabolism<br/>Rod Cell Outer Segment--metabolism