TY  - GEN
AU  - Kiyono,T
AU  - Foster,S A
AU  - Koop,J I
AU  - McDougall,J K
AU  - Galloway,D A
AU  - Klingelhutz,A J
TI  - Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells
SN  - 0028-0836
PY  - 1998///1120
KW  - Breast
KW  - cytology
KW  - Cell Transformation, Neoplastic
KW  - Cell Transformation, Viral
KW  - Cells, Cultured
KW  - Cellular Senescence
KW  - physiology
KW  - Cyclin-Dependent Kinase Inhibitor p16
KW  - antagonists & inhibitors
KW  - DNA-Binding Proteins
KW  - Enzyme Induction
KW  - Humans
KW  - Keratinocytes
KW  - Oncogene Proteins, Viral
KW  - Proteins
KW  - RNA
KW  - Repressor Proteins
KW  - Retinoblastoma Protein
KW  - Telomerase
N1  - Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S
UR  - https://doi.org/10.1038/23962
ER  -