Kiyono, T <br/><br/>
Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.  [electronic resource] 

 -  Nature  Nov 1998 
 - 84-8 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S. 
<br/><br/><label>ISSN: </label>0028-0836 
<br/><br/><label>Standard No.: </label>10.1038/23962  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Breast--cytology<br/>Cell Transformation, Neoplastic<br/>Cell Transformation, Viral<br/>Cells, Cultured<br/>Cellular Senescence--physiology<br/>Cyclin-Dependent Kinase Inhibitor p16--antagonists & inhibitors<br/>DNA-Binding Proteins<br/>Enzyme Induction<br/>Humans<br/>Keratinocytes--cytology<br/>Oncogene Proteins, Viral--physiology<br/>Proteins--physiology<br/>RNA<br/>Repressor Proteins<br/>Retinoblastoma Protein--antagonists & inhibitors<br/>Telomerase--physiology