Surmacz, E

Overexpression of insulin receptor substrate 1 (IRS-1) in the human breast cancer cell line MCF-7 induces loss of estrogen requirements for growth and transformation. [electronic resource] - Clinical cancer research : an official journal of the American Association for Cancer Research Nov 1995 - 1429-36 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

1078-0432


Breast Neoplasms--metabolism
Cell Adhesion--drug effects
Cell Division--drug effects
Cell Transformation, Neoplastic--metabolism
Estrogens--pharmacology
Female
Genetic Vectors
Humans
Insulin Receptor Substrate Proteins
Insulin-Like Growth Factor I--metabolism
Neoplasm Proteins--genetics
Phosphoproteins--genetics
Receptor, Insulin--metabolism
Transfection
Tumor Cells, Cultured--drug effects
Tumor Stem Cell Assay