Gerber, H P
Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3'-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation. [electronic resource]
- The Journal of biological chemistry Nov 1998
- 30336-43 p. digital
Publication Type: Journal Article
ISSN: 0021-9258
Standard No.: 10.1074/jbc.273.46.30336 doi
Subjects--Topical Terms: Amino Acid Chloromethyl Ketones--pharmacology Apoptosis Cell Survival Cells, Cultured Cysteine Proteinase Inhibitors--pharmacology Endothelial Growth Factors--genetics Endothelium, Vascular--cytology Enzyme Activation Fibroblast Growth Factor 2--physiology Humans Lymphokines--genetics Mutagenesis, Site-Directed Phosphatidylinositol 3-Kinases--metabolism Phosphorylation Protein Serine-Threonine Kinases--metabolism Proto-Oncogene Proteins--metabolism Proto-Oncogene Proteins c-akt Receptor Protein-Tyrosine Kinases--metabolism Receptors, Growth Factor--metabolism Receptors, Vascular Endothelial Growth Factor Signal Transduction Vascular Endothelial Growth Factor A Vascular Endothelial Growth Factor Receptor-1 Vascular Endothelial Growth Factors