Ikeda, K

Neuronal nitric oxide synthase inhibitor, 7-nitroindazole, delays motor dysfunction and spinal motoneuron degeneration in the wobbler mouse. [electronic resource] - Journal of the neurological sciences Sep 1998 - 9-15 p. digital

Publication Type: Journal Article

0022-510X

10.1016/s0022-510x(98)00224-x doi


Amyotrophic Lateral Sclerosis
Animals
Disease Models, Animal
Dose-Response Relationship, Drug
Drug Evaluation, Preclinical
Enzyme Inhibitors--administration & dosage
Hand Strength
Indazoles--administration & dosage
Mice
Mice, Neurologic Mutants
Motor Neuron Disease--genetics
Motor Neurons--pathology
Muscle Denervation
Muscle, Skeletal--pathology
NG-Nitroarginine Methyl Ester--pharmacology
Nerve Tissue Proteins--antagonists & inhibitors
Nitric Oxide Synthase--antagonists & inhibitors
Nitric Oxide Synthase Type I
Organ Size--drug effects
Vacuoles--ultrastructure