Wu, E S

Synthesis and modeling studies of a potent conformationally rigid muscarinic agonist: 1-azabicyclo[2.2.1]heptanespirofuranone. [electronic resource] - Journal of medicinal chemistry Oct 1998 - 4181-5 p. digital

Publication Type: Journal Article

0022-2623

10.1021/jm980192x doi


Animals
Bridged Bicyclo Compounds, Heterocyclic--chemical synthesis
Crystallography, X-Ray
Cyclic AMP--biosynthesis
Guinea Pigs
Hippocampus--drug effects
Hydrolysis
In Vitro Techniques
Models, Molecular
Molecular Conformation
Muscarinic Agonists--chemical synthesis
Myocardium--metabolism
Phosphatidylinositols--metabolism
Rats
Spiro Compounds--chemical synthesis
Structure-Activity Relationship