Witiak, D T

Diethyl (4baalpha,4calpha,9aalpha,9balpha)-3,6-dichlorocyclobuta[1,2-b:3,4-b']bisbenzofuran-9a,9b(4bH,4cH)-dicarboxylate: the cis,syn photodimer of ethyl 5-chlorobenzofuran-2-carboxylate, an analogue related to the antilipidemic drug clofibrate. [electronic resource] - Journal of medicinal chemistry Aug 1978 - 833-7 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.

0022-2623

10.1021/jm00206a026 doi


Animals
Benzofurans--chemical synthesis
Cholesterol--blood
Clofibrate--pharmacology
Cyclobutanes--chemical synthesis
Ethylmorphine-N-Demethylase--metabolism
Hydroxymethylglutaryl CoA Reductases--metabolism
Hyperlipidemias--blood
Hypolipidemic Agents--chemical synthesis
Liver--drug effects
Male
Microsomes, Liver--drug effects
Molecular Conformation
NADPH-Ferrihemoprotein Reductase--metabolism
Organ Size--drug effects
Rats
Sucrose--pharmacology
Triglycerides--blood