TY - GEN AU - Neumann,A U AU - Lam,N P AU - Dahari,H AU - Gretch,D R AU - Wiley,T E AU - Layden,T J AU - Perelson,A S TI - Hepatitis C viral dynamics in vivo and the antiviral efficacy of interferon-alpha therapy SN - 0036-8075 PY - 1998///1016 KW - Alanine Transaminase KW - blood KW - Antiviral Agents KW - administration & dosage KW - Cell Death KW - Dose-Response Relationship, Drug KW - Half-Life KW - Hepacivirus KW - physiology KW - Hepatitis C KW - immunology KW - Humans KW - Interferon alpha-2 KW - Interferon-alpha KW - Kinetics KW - Models, Biological KW - RNA, Viral KW - Recombinant Proteins KW - Regression Analysis KW - Viral Load KW - Viremia KW - virology KW - Virion KW - Virus Replication N1 - Publication Type: Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1126/science.282.5386.103 ER -