TY - GEN AU - Fry,D W AU - Bridges,A J AU - Denny,W A AU - Doherty,A AU - Greis,K D AU - Hicks,J L AU - Hook,K E AU - Keller,P R AU - Leopold,W R AU - Loo,J A AU - McNamara,D J AU - Nelson,J M AU - Sherwood,V AU - Smaill,J B AU - Trumpp-Kallmeyer,S AU - Dobrusin,E M TI - Specific, irreversible inactivation of the epidermal growth factor receptor and erbB2, by a new class of tyrosine kinase inhibitor SN - 0027-8424 PY - 1998///1022 KW - Animals KW - Antineoplastic Agents KW - chemistry KW - Binding Sites KW - genetics KW - Cell Line KW - Cysteine KW - Enzyme Inhibitors KW - ErbB Receptors KW - antagonists & inhibitors KW - Humans KW - Mice KW - Mice, Nude KW - Models, Molecular KW - Mutagenesis, Site-Directed KW - Neoplasm Transplantation KW - Neoplasms, Experimental KW - drug therapy KW - Protein Conformation KW - Protein-Tyrosine Kinases KW - Quinazolines KW - Receptor, ErbB-2 KW - Recombinant Fusion Proteins KW - Transplantation, Heterologous KW - Tumor Cells, Cultured N1 - Publication Type: Journal Article UR - https://doi.org/10.1073/pnas.95.20.12022 ER -