TY - GEN AU - Hsueh,C T AU - Kelsen,D AU - Schwartz,G K TI - UCN-01 suppresses thymidylate synthase gene expression and enhances 5-fluorouracil-induced apoptosis in a sequence-dependent manner SN - 1078-0432 PY - 1998///1120 KW - Alkaloids KW - administration & dosage KW - Antimetabolites, Antineoplastic KW - Antineoplastic Combined Chemotherapy Protocols KW - pharmacology KW - Apoptosis KW - drug effects KW - Carrier Proteins KW - Cell Cycle Proteins KW - Cyclin-Dependent Kinases KW - antagonists & inhibitors KW - DNA-Binding Proteins KW - Down-Regulation KW - Drug Administration Schedule KW - Drug Synergism KW - E2F Transcription Factors KW - E2F1 Transcription Factor KW - Enzyme Inhibitors KW - Fluorouracil KW - Gene Expression KW - Humans KW - Protein Kinase C KW - Retinoblastoma-Binding Protein 1 KW - Staurosporine KW - analogs & derivatives KW - Stomach Neoplasms KW - drug therapy KW - Thymidylate Synthase KW - biosynthesis KW - Transcription Factor DP1 KW - Transcription Factors KW - metabolism KW - Tumor Cells, Cultured N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S ER -