Lewis, D F

Molecular modelling of steroidogenic cytochromes P450 from families CYP11, CYP17, CYP19 and CYP21 based on the CYP102 crystal structure. [electronic resource] - The Journal of steroid biochemistry and molecular biology Aug 1998 - 217-33 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0960-0760

10.1016/s0960-0760(98)00032-6 doi


Amino Acid Sequence
Animals
Aromatase--chemistry
Bacterial Proteins
Binding Sites
Cattle
Computer Graphics
Conserved Sequence
Crystallography, X-Ray
Cytochrome P-450 Enzyme System--chemistry
Hormones--biosynthesis
Humans
Hydrogen Bonding
Mixed Function Oxygenases
Models, Molecular
Molecular Sequence Data
Mutagenesis, Site-Directed
NADPH-Ferrihemoprotein Reductase
Point Mutation
Protein Conformation
Protein Structure, Secondary
Recombinant Proteins--chemistry
Sequence Alignment
Sequence Homology, Amino Acid
Steroid 11-beta-Hydroxylase--chemistry
Steroid 17-alpha-Hydroxylase--chemistry
Steroid 21-Hydroxylase--chemistry
Steroids--biosynthesis
Thermodynamics