TY - GEN AU - Wang,H AU - Dick,R AU - Yin,H AU - Licad-Coles,E AU - Kroetz,D L AU - Szklarz,G AU - Harlow,G AU - Halpert,J R AU - Correia,M A TI - Structure-function relationships of human liver cytochromes P450 3A: aflatoxin B1 metabolism as a probe SN - 0006-2960 PY - 1999///0205 KW - Aflatoxin B1 KW - metabolism KW - Amino Acid Sequence KW - Animals KW - Aryl Hydrocarbon Hydroxylases KW - Binding Sites KW - genetics KW - Computer Simulation KW - Cytochrome P-450 CYP3A KW - Cytochrome P-450 Enzyme System KW - chemistry KW - Cytochromes b5 KW - Humans KW - Male KW - Microsomes, Liver KW - enzymology KW - Models, Molecular KW - Molecular Sequence Data KW - Mutagenesis, Site-Directed KW - NADPH-Ferrihemoprotein Reductase KW - Oxidoreductases, N-Demethylating KW - Rats KW - Recombinant Proteins KW - biosynthesis KW - Stereoisomerism KW - Steroid Hydroxylases KW - Structure-Activity Relationship N1 - Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1021/bi980895g ER -