TY - GEN AU - Patrick,G N AU - Zhou,P AU - Kwon,Y T AU - Howley,P M AU - Tsai,L H TI - p35, the neuronal-specific activator of cyclin-dependent kinase 5 (Cdk5) is degraded by the ubiquitin-proteasome pathway SN - 0021-9258 PY - 1998///1013 KW - Acetylcysteine KW - analogs & derivatives KW - Animals KW - COS Cells KW - Cells, Cultured KW - Cerebral Cortex KW - metabolism KW - Cyclin-Dependent Kinase 5 KW - Cyclin-Dependent Kinases KW - Cysteine Endopeptidases KW - Embryo, Mammalian KW - Enzyme Activation KW - Enzyme Inhibitors KW - pharmacology KW - Half-Life KW - Humans KW - Kinetics KW - Mammals KW - Mice KW - Multienzyme Complexes KW - Nerve Tissue Proteins KW - genetics KW - Neurons KW - cytology KW - Polymerase Chain Reaction KW - Proteasome Endopeptidase Complex KW - Protein Serine-Threonine Kinases KW - antagonists & inhibitors KW - Purines KW - Rats KW - Rats, Sprague-Dawley KW - Recombinant Proteins KW - Roscovitine KW - Sequence Deletion KW - Transfection KW - Ubiquitins N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1074/jbc.273.37.24057 ER -