Borrell, J I

Synthesis and biological activity of 4-amino-7-oxo-substituted analogues of 5-deaza-5,6,7,8-tetrahydrofolic acid and 5,10-dideaza-5, 6,7,8-tetrahydrofolic acid. [electronic resource] - Journal of medicinal chemistry Aug 1998 - 3539-45 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0022-2623

10.1021/jm9801298 doi


Antimetabolites, Antineoplastic--chemical synthesis
Antineoplastic Agents--chemical synthesis
Cell Survival--drug effects
Drug Screening Assays, Antitumor
Folic Acid Antagonists--chemical synthesis
Humans
Structure-Activity Relationship
Tetrahydrofolates--chemical synthesis
Tumor Cells, Cultured