TY  - GEN
AU  - Klutchko,S R
AU  - Hamby,J M
AU  - Boschelli,D H
AU  - Wu,Z
AU  - Kraker,A J
AU  - Amar,A M
AU  - Hartl,B G
AU  - Shen,C
AU  - Klohs,W D
AU  - Steinkampf,R W
AU  - Driscoll,D L
AU  - Nelson,J M
AU  - Elliott,W L
AU  - Roberts,B J
AU  - Stoner,C L
AU  - Vincent,P W
AU  - Dykes,D J
AU  - Panek,R L
AU  - Lu,G H
AU  - Major,T C
AU  - Dahring,T K
AU  - Hallak,H
AU  - Bradford,L A
AU  - Showalter,H D
AU  - Doherty,A M
TI  - 2-Substituted aminopyrido[2,3-d]pyrimidin-7(8H)-ones. structure-activity relationships against selected tyrosine kinases and in vitro and in vivo anticancer activity
SN  - 0022-2623
PY  - 1998///0909
KW  - 3T3 Cells
KW  - Animals
KW  - Antineoplastic Agents
KW  - chemical synthesis
KW  - Biotransformation
KW  - Cell Division
KW  - drug effects
KW  - Cisplatin
KW  - therapeutic use
KW  - Enzyme Inhibitors
KW  - Female
KW  - Humans
KW  - Male
KW  - Mice
KW  - Mice, Nude
KW  - Molecular Conformation
KW  - Molecular Structure
KW  - Ovarian Neoplasms
KW  - drug therapy
KW  - Platelet-Derived Growth Factor
KW  - pharmacology
KW  - Protein-Tyrosine Kinases
KW  - antagonists & inhibitors
KW  - Pyrimidinones
KW  - Rats
KW  - Receptor Protein-Tyrosine Kinases
KW  - Structure-Activity Relationship
KW  - Transplantation, Heterologous
KW  - Tumor Cells, Cultured
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1021/jm9802259
ER  -