Xu, R

Synthesis and pharmacological characterization of O-alkynyloximes of tropinone and N-methylpiperidinone as muscarinic agonists. [electronic resource] - Journal of medicinal chemistry Aug 1998 - 3220-31 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0022-2623

10.1021/jm9708588 doi


Animals
Aorta--drug effects
Binding, Competitive
Drug Design
Escape Reaction--drug effects
In Vitro Techniques
Male
Maze Learning--drug effects
Mice
Models, Molecular
Molecular Structure
Muscarinic Agonists--chemical synthesis
Muscle Contraction--drug effects
Muscle, Smooth, Vascular--drug effects
N-Methylscopolamine--pharmacology
Nuclear Magnetic Resonance, Biomolecular
Piperidines--chemical synthesis
Pirenzepine--metabolism
Rabbits
Rats
Rats, Sprague-Dawley
Receptors, Muscarinic--drug effects
Structure-Activity Relationship
Tropanes--chemical synthesis