TY  - GEN
AU  - Ko,J W
AU  - Desta,Z
AU  - Flockhart,D A
TI  - Human N-demethylation of (S)-mephenytoin by cytochrome P450s 2C9 and 2B6
SN  - 0090-9556
PY  - 1998///0831
KW  - Anticonvulsants
KW  - metabolism
KW  - Aryl Hydrocarbon Hydroxylases
KW  - Cytochrome P-450 CYP2B6
KW  - Cytochrome P-450 CYP2C9
KW  - Cytochrome P-450 Enzyme System
KW  - Humans
KW  - Isoenzymes
KW  - Kinetics
KW  - Mephenytoin
KW  - analogs & derivatives
KW  - Methylation
KW  - Microsomes, Liver
KW  - Oxidoreductases, N-Demethylating
KW  - Phenotype
KW  - Stereoisomerism
KW  - Steroid 16-alpha-Hydroxylase
KW  - Steroid Hydroxylases
KW  - Substrate Specificity
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S
ER  -