Ko, J W

Human N-demethylation of (S)-mephenytoin by cytochrome P450s 2C9 and 2B6. [electronic resource] - Drug metabolism and disposition: the biological fate of chemicals Aug 1998 - 775-8 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0090-9556


Anticonvulsants--metabolism
Aryl Hydrocarbon Hydroxylases
Cytochrome P-450 CYP2B6
Cytochrome P-450 CYP2C9
Cytochrome P-450 Enzyme System--metabolism
Humans
Isoenzymes--metabolism
Kinetics
Mephenytoin--analogs & derivatives
Methylation
Microsomes, Liver--metabolism
Oxidoreductases, N-Demethylating--metabolism
Phenotype
Stereoisomerism
Steroid 16-alpha-Hydroxylase
Steroid Hydroxylases--metabolism
Substrate Specificity