Kudo, S
Involvement of human cytochrome P450 3A4 in reduced haloperidol oxidation. [electronic resource]
- European journal of clinical pharmacology May 1998
- 253-9 p. digital
Publication Type: Journal Article
ISSN: 0031-6970
Standard No.: 10.1007/s002280050455 doi
Subjects--Topical Terms: Anti-Arrhythmia Agents--pharmacology Anti-Bacterial Agents--administration & dosage Antiparkinson Agents--pharmacology Biotransformation--drug effects Biperiden--pharmacology Carteolol--metabolism Cell Line, Transformed Cytochrome P-450 CYP2D6--metabolism Cytochrome P-450 CYP2D6 Inhibitors Cytochrome P-450 CYP3A Cytochrome P-450 Enzyme Inhibitors Cytochrome P-450 Enzyme System--metabolism Dose-Response Relationship, Drug Haloperidol--antagonists & inhibitors Humans Hydroxylation--drug effects Isoenzymes--antagonists & inhibitors Kinetics Microsomes--drug effects Mixed Function Oxygenases--antagonists & inhibitors Oxidation-Reduction--drug effects Quinidine--pharmacology Sparteine--pharmacology Troleandomycin--administration & dosage