TY - GEN AU - Humpf,H U AU - Schmelz,E M AU - Meredith,F I AU - Vesper,H AU - Vales,T R AU - Wang,E AU - Menaldino,D S AU - Liotta,D C AU - Merrill,A H TI - Acylation of naturally occurring and synthetic 1-deoxysphinganines by ceramide synthase. Formation of N-palmitoyl-aminopentol produces a toxic metabolite of hydrolyzed fumonisin, AP1, and a new category of ceramide synthase inhibitor SN - 0021-9258 PY - 1998///0820 KW - Acylation KW - Carboxylic Acids KW - chemistry KW - Fumonisins KW - Humans KW - Hydrolysis KW - Kinetics KW - Mycotoxins KW - Oxidoreductases KW - antagonists & inhibitors KW - Palmitic Acid KW - metabolism KW - Pancreatitis-Associated Proteins KW - Sphingosine KW - analogs & derivatives N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1074/jbc.273.30.19060 ER -