TY  - GEN
AU  - Dragovich,P S
AU  - Webber,S E
AU  - Babine,R E
AU  - Fuhrman,S A
AU  - Patick,A K
AU  - Matthews,D A
AU  - Lee,C A
AU  - Reich,S H
AU  - Prins,T J
AU  - Marakovits,J T
AU  - Littlefield,E S
AU  - Zhou,R
AU  - Tikhe,J
AU  - Ford,C E
AU  - Wallace,M B
AU  - Meador,J W
AU  - Ferre,R A
AU  - Brown,E L
AU  - Binford,S L
AU  - Harr,J E
AU  - DeLisle,D M
AU  - Worland,S T
TI  - Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 1. Michael acceptor structure-activity studies
SN  - 0022-2623
PY  - 1998///0803
KW  - 3C Viral Proteases
KW  - Animals
KW  - Antiviral Agents
KW  - chemical synthesis
KW  - Binding Sites
KW  - Cell Line, Transformed
KW  - Crystallography, X-Ray
KW  - Cysteine Endopeptidases
KW  - chemistry
KW  - Cysteine Proteinase Inhibitors
KW  - Drug Design
KW  - Drug Stability
KW  - HeLa Cells
KW  - Humans
KW  - Oligopeptides
KW  - Protein Conformation
KW  - Rats
KW  - Rats, Sprague-Dawley
KW  - Rhinovirus
KW  - drug effects
KW  - Structure-Activity Relationship
KW  - Viral Proteins
N1  - Publication Type: Comparative Study; Journal Article
UR  - https://doi.org/10.1021/jm980068d
ER  -